Staff scientist (AC-TAP) in Chromatin Replication and Epigenomics in the Groth Group at...
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We are looking for a highly motivated and independent staff scientist with extensive experience in cutting edge genomics technologies and data analysis to support our efforts in dissecting principles of epigenetic cell memory in mammals.
Our research
Our research goal is to understand how chromatin is replicated to ensure faithful transmission of genetic and epigenetic information. We are focusing on mechanisms involved in replication-coupled chromatin dynamics, propagation of histone-based information and the importance of new unmarked histones in identifying post-replicative chromatin for error-free DNA repair. To this end we are applying innovative proteomic and genomic approaches in combination with cutting-edge cell biology, advanced high-content imaging, single molecule analysis of replicating DNA, biochemistry and structural biology.
Recent publications include:
Stewart-Morgan et al., Mol Cell 2019
Nakamura et al., Nat Cell Biol 2019
Petryk et al., Science 2018
Reveron-Gomez et al., Mol Cell 2018
Saredi et al., Nature 2016
Alabert et al., Genes Dev 2015
Huang et al., Nat Struct Mol Biol 2015
Alabert et al., Nat Cell Biol 2014
The Groth group is an interdisciplinary team of postdocs and PhD students. We put high value on idea sharing and collaborative research both within the group and externally (e.g. structural biology, proteomics, etc.). We have annual retreats with focus on research strategy, collaborative skills and team dynamics, and have implemented Creative Problem Solving as a tool to develop our research projects.
Your job
You will join a multi-disciplinary research team working on how epigenetic information is transmitted in proliferating cells. In particular, the lab has developed a panel of genomic tools to interrogate the impact of DNA replication on the epigenome. Your tasks will include epigenome profiling using diverse cutting-edge functional genomics tools (e.g., ChIP-seq, ChOR-seq, ATAC-seq, RNA-seq, HiC-seq) including data analysis. You will engage in developing new experimental approaches and data analysis tools for our ongoing and future projects. You will also support cell biology and genome editing activities in the group. You will be expected to contribute to and support the research projects in the group and collaborative work on an ad hoc basis; disseminate your expertise to new lab members, interact with core facilities and support the lab management.
Profile
We are looking for a highly motivated and enthusiastic staff scientist with the following competencies and experience:
Essential experience and skills
The ideal candidate will be a team player and have excellent communication skills.
Place of employment
The employment is at BRIC, University of Copenhagen. The Biotech Research and Innovation Centre (BRIC) is a research centre of excellence for biomedical research, focusing on disease-oriented basic research, at the Faculty of Health and Medical Sciences, University of Copenhagen. BRIC hosts 25 independent research groups that perform basic and translational research aimed to understand diseases like cancer, neurological and metabolic disorders. For further information about the Groth group and BRIC: http://www.bric.ku.dk/.
We offer creative and stimulating working conditions in dynamic and international research environment. We have weekly journal clubs, data clubs, seminars with invited speakers and a young researchers club ASAP and our own PhD programme, MoMeD and a Postdoc Career Programme (PCP). BRIC has extensive international collaborations and actively participates in the European alliance, EU-life consisting of 13 excellent life science research institutions http://eu-life.eu/ and is part of the EU-funded LIBRA initiative http://www.eu-libra.eu to obtain gender balance in life science research.
BRIC has a highly international profile (more than 60% international researchers) and English as working language. An International Staff Mobility Office at UCPH supports and guides international researchers through your initial steps in Denmark (e.g. residence and work permits, tax and pension, banking, medical care, childcare). They also offer a dual career network open for spouses of our researchers.
Terms of salary and employment
The employment as ‘staff scientist’ (AC-TAP) is a full time and permanent position. Starting date is 1 October 2019 or after agreement. Employment will be in accordance with the provisions of the collective agreement between the Danish Ministry of Finance and AC (the Danish Confederation of Professional Associations). The monthly salary will be based on the number of years of work experience (seniority) with the possibility to negotiate a salary supplement based on prior experiences and qualifications. The employer will pay an additional 17.1 % to your pension fund.
Questions
For further information regarding the position, please contact Anja Groth; e-mail [email protected].
Application
Your application should be in English and include:
Please submit your application by clicking on “Apply Now” below.
Application deadline: 5 August 2019, 23.59 CET
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
Interviews are expected to be held in August 2019.
The University of Copenhagen wish to reflect the diversity of society and encourage all qualified candidates to apply regardless of personal background.
Kilde: Jobnet.dk
Our research
Our research goal is to understand how chromatin is replicated to ensure faithful transmission of genetic and epigenetic information. We are focusing on mechanisms involved in replication-coupled chromatin dynamics, propagation of histone-based information and the importance of new unmarked histones in identifying post-replicative chromatin for error-free DNA repair. To this end we are applying innovative proteomic and genomic approaches in combination with cutting-edge cell biology, advanced high-content imaging, single molecule analysis of replicating DNA, biochemistry and structural biology.
Recent publications include:
Stewart-Morgan et al., Mol Cell 2019
Nakamura et al., Nat Cell Biol 2019
Petryk et al., Science 2018
Reveron-Gomez et al., Mol Cell 2018
Saredi et al., Nature 2016
Alabert et al., Genes Dev 2015
Huang et al., Nat Struct Mol Biol 2015
Alabert et al., Nat Cell Biol 2014
The Groth group is an interdisciplinary team of postdocs and PhD students. We put high value on idea sharing and collaborative research both within the group and externally (e.g. structural biology, proteomics, etc.). We have annual retreats with focus on research strategy, collaborative skills and team dynamics, and have implemented Creative Problem Solving as a tool to develop our research projects.
Your job
You will join a multi-disciplinary research team working on how epigenetic information is transmitted in proliferating cells. In particular, the lab has developed a panel of genomic tools to interrogate the impact of DNA replication on the epigenome. Your tasks will include epigenome profiling using diverse cutting-edge functional genomics tools (e.g., ChIP-seq, ChOR-seq, ATAC-seq, RNA-seq, HiC-seq) including data analysis. You will engage in developing new experimental approaches and data analysis tools for our ongoing and future projects. You will also support cell biology and genome editing activities in the group. You will be expected to contribute to and support the research projects in the group and collaborative work on an ad hoc basis; disseminate your expertise to new lab members, interact with core facilities and support the lab management.
Profile
We are looking for a highly motivated and enthusiastic staff scientist with the following competencies and experience:
Essential experience and skills
- You have a PhD in Life sciences or related
- You have documented experience in functional genomics tools (e.g., ChIP-seq, ATAC-seq, RNA-seq, Hi-seq), cell biology, molecular and biochemical techniques
- You have documented expertise in NGS data workflow and analysis (e.g., Galaxy, Seqmonk etc.)
- You have knowledge in programming (e.g., Python, R etc.)
- You have an active interest and background in chromatin biology, epigenomics or cancer genomics
- You have proven an ability to envision, plan and execute a research project
- Good organization and flexibility
- Excellent English skills, written and spoken
The ideal candidate will be a team player and have excellent communication skills.
Place of employment
The employment is at BRIC, University of Copenhagen. The Biotech Research and Innovation Centre (BRIC) is a research centre of excellence for biomedical research, focusing on disease-oriented basic research, at the Faculty of Health and Medical Sciences, University of Copenhagen. BRIC hosts 25 independent research groups that perform basic and translational research aimed to understand diseases like cancer, neurological and metabolic disorders. For further information about the Groth group and BRIC: http://www.bric.ku.dk/.
We offer creative and stimulating working conditions in dynamic and international research environment. We have weekly journal clubs, data clubs, seminars with invited speakers and a young researchers club ASAP and our own PhD programme, MoMeD and a Postdoc Career Programme (PCP). BRIC has extensive international collaborations and actively participates in the European alliance, EU-life consisting of 13 excellent life science research institutions http://eu-life.eu/ and is part of the EU-funded LIBRA initiative http://www.eu-libra.eu to obtain gender balance in life science research.
BRIC has a highly international profile (more than 60% international researchers) and English as working language. An International Staff Mobility Office at UCPH supports and guides international researchers through your initial steps in Denmark (e.g. residence and work permits, tax and pension, banking, medical care, childcare). They also offer a dual career network open for spouses of our researchers.
Terms of salary and employment
The employment as ‘staff scientist’ (AC-TAP) is a full time and permanent position. Starting date is 1 October 2019 or after agreement. Employment will be in accordance with the provisions of the collective agreement between the Danish Ministry of Finance and AC (the Danish Confederation of Professional Associations). The monthly salary will be based on the number of years of work experience (seniority) with the possibility to negotiate a salary supplement based on prior experiences and qualifications. The employer will pay an additional 17.1 % to your pension fund.
Questions
For further information regarding the position, please contact Anja Groth; e-mail [email protected].
Application
Your application should be in English and include:
- Letter of application addressing the requirements (max. one page).
- Curriculum Vitae
- Complete publication list
- Copies of relevant certificate(s) of education
Please submit your application by clicking on “Apply Now” below.
Application deadline: 5 August 2019, 23.59 CET
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
Interviews are expected to be held in August 2019.
The University of Copenhagen wish to reflect the diversity of society and encourage all qualified candidates to apply regardless of personal background.
Kilde: Jobnet.dk
Information og data
Denne ledige stilling har jobtypen "Akademisk medarbejder", og befinder sig i kategorien "Økonomi og jura".
Arbejdsstedet er beliggende i København N.
Jobbet er oprettet på vores service den 16.7.2019, men kan have været deaktiveret og genaktiveret igen.
Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
- Akademisk medarbejder
- København N
- Mandag den 05. august 2019
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