Staff Scientist in Organoid Research at BRIC
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København N
Faculty of Health and Medical Sciences
University of Copenhagen
We are looking for a highly motivated and independent Staff Scientist to support our efforts in organoid research to commence 1 October 2019.
The group and our research
The intestinal epithelium is a rapidly self-renewing tissue, where stem cells have been shown to play an important role during tissue replenishment. Deregulation of the natural process of tissue replenishment is associated with diseases such as cancer and ulceration, as well as regeneration following injury. We believe that molecular insights into how cells normally transition from a state characterized by tissue growth to a homeostatic state will be vital to understand, what happens at the cellular level during tissue regeneration and the development of cancer (Wong et al., 2012, Nature Cell Biology; Yui et al., 2018, Cell Stem Cell; Fordham et al., 2013, Cell Stem Cell; Guiu et al., 2019, Nature). In order to address these key questions we use a number of different techniques including in vivo fate mapping to define cellular heritage, transcriptional and epigenetic analysis at both bulk populations and single cell level to identify candidate genes regulating cell fate changes, mouse models and organoid culture systems to identify signalling pathways that control cellular identity, transplantation techniques to address cell potential, bioengineered 3D cell culture scaffold to address how the environment affects cell fate and Crispr/Cas9 mediated genetic perturbation to address the role of specific genes and mutations (Page et al., 2013, Cell Stem Cell; Fordham et al., 2013, Cell Stem Cell; Yui et al., 2018, Cell Stem Cell).
For more information on the Jensen Group, please follow the link http://www.bric.ku.dk/Research/jensen_group/.
Your job
As our Staff Scientist, you will assist the group’s researchers on studies of stem cells in the intestinal epithelium:
Furthermore, you will be responsible for maintaining our cellular laboratory and manufacturing of our many different media components. You will be expected to contribute to and support the ongoing research projects in the group on an ad hoc basis when needed; disseminate your expertise to new lab members and support the lab management.
Please notice that the position is not a research position but technical on an advanced level.
Profile
We are looking for a highly motivated and ambitious Staff scientist with the following qualifications:
Essential experience and skills
About BRIC
BRIC is located in the Biocenter, close to the centre of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and a number of core facilities shared between the 26 research groups at BRIC and the neighbouring Finsen laboratory. We have weekly journal clubs, data clubs, seminars with invited speakers, young researchers club ASAP and our own PhD programme, MoMeD.
Terms of salary and employment
The employment as Staff Scientist (AC-TAP) is a full time (37h/week) and fixed-term position for up to 15 months, until the end of 2020. Starting date is 1 October 2019 or after agreement. Employment will be in accordance with the provisions of the collective agreement between the Danish Ministry of Finance and AC (the Danish Confederation of Professional Associations). The monthly salary will be based on the number of years of work experience (seniority) with the possibility to negotiate a salary supplement based on prior experiences and qualifications. The employer will pay an additional 17.1 % to your pension fund.
Questions
For further information regarding the position, please do not hesitate to contact Associate Professor Kim Jensen at [email protected].
Application
Your application, in English, should include:
Please submit your application by clicking on “Apply Now” below. Only online applications will be accepted.
Application deadline: 1 August 2019 at 23.59 CET.
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
Interviews are expected to be held in week 33.
University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates regardless of age, disability, gender, nationality, race, religion or sexual orientation. Appointment will be based on merit alone.
Kilde: Jobnet.dk
University of Copenhagen
We are looking for a highly motivated and independent Staff Scientist to support our efforts in organoid research to commence 1 October 2019.
The group and our research
The intestinal epithelium is a rapidly self-renewing tissue, where stem cells have been shown to play an important role during tissue replenishment. Deregulation of the natural process of tissue replenishment is associated with diseases such as cancer and ulceration, as well as regeneration following injury. We believe that molecular insights into how cells normally transition from a state characterized by tissue growth to a homeostatic state will be vital to understand, what happens at the cellular level during tissue regeneration and the development of cancer (Wong et al., 2012, Nature Cell Biology; Yui et al., 2018, Cell Stem Cell; Fordham et al., 2013, Cell Stem Cell; Guiu et al., 2019, Nature). In order to address these key questions we use a number of different techniques including in vivo fate mapping to define cellular heritage, transcriptional and epigenetic analysis at both bulk populations and single cell level to identify candidate genes regulating cell fate changes, mouse models and organoid culture systems to identify signalling pathways that control cellular identity, transplantation techniques to address cell potential, bioengineered 3D cell culture scaffold to address how the environment affects cell fate and Crispr/Cas9 mediated genetic perturbation to address the role of specific genes and mutations (Page et al., 2013, Cell Stem Cell; Fordham et al., 2013, Cell Stem Cell; Yui et al., 2018, Cell Stem Cell).
For more information on the Jensen Group, please follow the link http://www.bric.ku.dk/Research/jensen_group/.
Your job
As our Staff Scientist, you will assist the group’s researchers on studies of stem cells in the intestinal epithelium:
- Work with organoid models from human and mouse
- Analysis of tissue from animal models
- General lab support
Furthermore, you will be responsible for maintaining our cellular laboratory and manufacturing of our many different media components. You will be expected to contribute to and support the ongoing research projects in the group on an ad hoc basis when needed; disseminate your expertise to new lab members and support the lab management.
Please notice that the position is not a research position but technical on an advanced level.
Profile
We are looking for a highly motivated and ambitious Staff scientist with the following qualifications:
Essential experience and skills
- Education preferable at least at masters level
- Formal training and experience in maintenance of primary cells from human and mouse as organoids is a requirement
- Practical experience in a wide range of modern molecular and cellular biology techniques is an advantage.
- You have proven an ability to envision, plan and execute a research project.
- Structured, responsible and self-motivated
- Collaborative and excellent communication skills in English
About BRIC
BRIC is located in the Biocenter, close to the centre of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and a number of core facilities shared between the 26 research groups at BRIC and the neighbouring Finsen laboratory. We have weekly journal clubs, data clubs, seminars with invited speakers, young researchers club ASAP and our own PhD programme, MoMeD.
Terms of salary and employment
The employment as Staff Scientist (AC-TAP) is a full time (37h/week) and fixed-term position for up to 15 months, until the end of 2020. Starting date is 1 October 2019 or after agreement. Employment will be in accordance with the provisions of the collective agreement between the Danish Ministry of Finance and AC (the Danish Confederation of Professional Associations). The monthly salary will be based on the number of years of work experience (seniority) with the possibility to negotiate a salary supplement based on prior experiences and qualifications. The employer will pay an additional 17.1 % to your pension fund.
Questions
For further information regarding the position, please do not hesitate to contact Associate Professor Kim Jensen at [email protected].
Application
Your application, in English, should include:
- Motivated letter of application (max. 1 page)
- Curriculum vitae incl. education, experience, language skills and other skills relevant for the position
- A certified/signed copy of your Master of Science certificate (max. 2 pages)
- Publication list if possible
Please submit your application by clicking on “Apply Now” below. Only online applications will be accepted.
Application deadline: 1 August 2019 at 23.59 CET.
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
Interviews are expected to be held in week 33.
University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates regardless of age, disability, gender, nationality, race, religion or sexual orientation. Appointment will be based on merit alone.
Kilde: Jobnet.dk
Information og data
Denne ledige stilling har jobtypen "Akademisk medarbejder", og befinder sig i kategorien "Økonomi og jura".
Arbejdsstedet er beliggende i København N.
Jobbet er oprettet på vores service den 18.7.2019, men kan have været deaktiveret og genaktiveret igen.
Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
- Akademisk medarbejder
- København N
- Torsdag den 01. august 2019
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