Senior Bioinformatician needed at Aalborg University Hospital

We are looking for a talented and motivated bioinformatician for our bioinformatics project portfolio within analyses of omics- and CRISPR screen data at the department of Haematology, Aalborg University Hospital. The position is open for one year from 1 April 2022 or soon hereafter – with a good chance of extension.

About the position
The overall aim of our project portfolio is to improve the identification and biological understanding of DNA damage repair deficient tumours in selected groups of cancer patients, particularly lymphoma, leukaemia, and ovarian cancer, to optimise diagnostics, prognostics, and treatment decisions. To study this, we use a range of bioinformatical tools for analysis of data from various -omics techniques and cell line screens in combination with pre-clinical and clinical data.

The job will entail annotation and interpretation of tumour-genetic variants from DNA sequencing data, differential expression and pathway analysis of transcriptomic and proteomics data, analysis of sequencing data from global CRISPR screens, and data extraction of molecular, treatment, and clinical data from local and online accessible databases.

You will work in close collaboration with researchers and PhD students, from the departments of Haematology, Oncology and Molecular diagnostics, and will be responsible for the bioinformatical analysis, but will also take part in the planning of studies as well as contribute to writing scientific papers and acquiring funding. Furthermore, limited teaching and supervision duties within bioinformatics at the Faculty of Medicine, Aalborg University, may be expected.

We offer
We offer a rewarding and challenging job in an interdisciplinary environment. We strive for academic excellence in an environment characterised by collegial respect and academic freedom tempered by responsibility.

Qualification requirements
The position presupposes qualifications at PhD-level. The research potential of each applicant will be emphasized in the overall assessment.

• PhD in bioinformatics or a closely related field
• Experience with clinical bioinformatics
• Experience in programming in R or Python, and use of command line tools
• Experience with data management and analysis of large data sets
• Prior experience working with omics and RNA-seq data analysis
• Solid publication track record in bioinformatic journals as first or lead author
• Motivated by interdisciplinary research
• Excellent writing and communication skills in English with a good scientific vocabulary

The application must contain the following

• A motivated text wherein the reasons for applying, qualifications in relation to the position, and intentions and visions for the position are stated
• A current curriculum vitae including publications
• Copies of relevant diplomas (MSc, PhD)
• Scientific qualifications
• Dissemination qualifications, including participation on committees or boards, participation in organisations and the like
• Additional qualifications in relation to the position
• References/recommendations
• Personal data

About the department
Aalborg University Hospital is one of five highly specialized university hospitals in Denmark. It serves as a cooperation within healthcare between North Denmark Region and the Faculty of Medicine at Aalborg University. The close cooperation between Aalborg University and Aalborg University Hospital ensures health research, education, and innovation at an international level.

The Department of Haematology at Aalborg University Hospital and its associated laboratory is an active and ambitious research unit. We are dedicated to research projects in experimental and clinical haematology. The unit was established 16 years ago and has focus on molecular research, clinical epidemiology and real-world data studies, as well as data science. The Clinical Data Science Group, Department of Clinical Medicine, Aalborg University and Department of Haematology, Aalborg University Hospital, works primarily with methodological developments and applications of bioinformatics, biostatistics, machine learning, and data management within clinical research.

The research unit is highly interdisciplinary, employing biostatisticians as well as bioinformaticians, software developers, and data managers who work in collaboration with molecular biologists and health care personnel throughout the Danish health care sector. Based on real world health data and molecular biomarkers, the focus is currently on establishing scalable, national decision support tools for personalized medicine in cancer treatment and health economics benefit. The research unit also participates in the Danish National Research Foundation’s Center for Molecular Prediction of Inflammatory Bowels Disease (PREDICT), the Danish Comprehensive Cancer Center’s Research Centre for Precision Medicine in blood cancer, and the Novo Nordisk Foundation supported National Health Data Science Sandbox.

Useful information
For further information regarding the position, please contact professor in bioinformatics and statistics, Martin Bøgsted, tel.: +45 5092 5639, email: , associate professor in bioinformatics and statistics, Rasmus Froberg Brøndum, tel.: +45 5192 3437, email: or professor in molecular haematology, Karen Dybkær, tel.: +45 4131 7818, email: .

We expect to conduct job interviews during week 11, 2022.

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