Bioinformatician – Multi-omics integration

Novo Nordisk Foundation Center for Basic Metabolic Research
Faculty of Health and Medical Sciences
University of Copenhagen

We are looking to hire up to a highly motivated and dynamic bioinformatician or -statistician with an MSc or PhD to strengthen our analytical team. Candidates should have a degree in statistical genetics, bioinformatics, computational biology, machine learning, computer science, or a related field, with experience in integrating large-scale multimodal data, and have an interest in obesity, cardiometabolic disease, and precision health. The position is a 3-year position to start June 1, 2023, or after agreement.

Background
The vision of the Novo Nordisk Foundation Center for Basic Metabolic Research is to strengthen interdisciplinary research that transforms our basic understanding of the mechanisms underlying metabolic health and disease and apply this knowledge to new prevention and treatment strategies. Established in 2010, we moved into new laboratories, offices, and meeting rooms in the Maersk Tower in 2017.

The Center has approximately 260 employees who work across a wide range of biomedical disciplines in a highly collaborative, international research environment. You can read more about us here: www.cbmr.ku.dk.

Our group and research
The Loos Group aims to identify the key genetic and non-genetic determinants of body weight regulation to gain insight into the deeper layers of biology that underlie obesity and metabolism. Additionally, we aim to improve prediction, prevention, and treatment through the implementation of precision health strategies. You can read more about the Loos Group.

Your job
The successful candidate will manage large-scale multimodal data, including genetics and other-omics data, trajectory and longitudinal data, medical record data, and registry data, among others. They will establish pipelines for the efficient analysis and integration of high‐density genotyping/sequencing data, high-throughput proteomics, transcriptomics, and metabolomics data.

They will implement the latest software and streamline pipelines, support postdocs and PhD students in doing the same, and train others in the team with the data analysis, visualization, and interpretation of results. In addition, the candidate will contribute analyses to a range of ongoing national and international collaborations.

Successful candidates will have the opportunity to contribute to projects related to [1] variant-to-function translation of genetic loci, [2] using polygenic/genetic risk scores in cardiometabolic disease, [3] subtyping cardiometabolic disease using multi-omics data, [4] determine causal relationships using Mendelian randomization, among others.

Skills and qualifications
We are looking for highly motivated and enthusiastic researchers who, in addition to the desired expertise stated above, have the following skills and qualifications:

• a MSc in statistical genetics, bioinformatics, computational biology, machine learning, applied statistics/mathematics, computer science, or a related field.
• a strong computational background and experience in handling large-scale multimodal data, including genetics and other-omics data, trajectory and longitudinal data, medical record data, and registry data, among others.
• experience in (batch) HPC environments.
• strong skills in R and/or python.
• an active interest in obesity, cardiometabolic disease, physical activity, lifestyle, and precision health.
• proficient communication skills and ability to work in multi-disciplinary teams.
• experience in training and providing support to other researchers at different levels .
• excellent English communication skills, both written and spoken.

Place of employment
The place of employment is at the Novo Nordisk Foundation Center for Basic Metabolic Research, Maersk Tower, Panum Institute, University of Copenhagen. We offer creative and stimulating working conditions in a dynamic and international research environment.

Terms of employment
The employment as bioinformatician is a full-time and fixed-term position for 3 years. Starting date is June 1, 2023, or after agreement.

Employment will be as Academic Research Officer or Research Consultant in accordance with the provisions of the collective agreement between the Danish Ministry of Taxation and AC (the Danish Confederation of Professional Associations). The monthly salary will be based on the number of years of work experience (seniority) with the possibility to negotiate a salary supplement based on prior experiences and qualifications. The employer will pay an additional 17.1 % to your pension fund.

Questions
For further information, please contact Professor Ruth Loos at email [email protected]. For questions regarding the recruitment procedure, please contact SUND HR CBMR at [email protected].

International applicants may find these links useful www.ism.ku.dk (International Staff Mobility) and https://www.workindenmark.dk/.

Application procedure
Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:

1. Motivated letter of application (max. one page)

2. CV incl. education, work/research experience, language skills and other skills relevant for the position

3. A certified/signed copy of a Master of Science certificate.

4. List of publications (optional)

Application deadline: May 9, 2023, at 23.59pm CET.

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process
You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/.

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

The University of Copenhagen wishes to reflect the diversity of society and welcome applications from all qualified candidates regardless of personal background.

Kilde: Jobnet.dk