Research Scientist within the field of mass spectrometry and proteomics
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Hørsholm
Would you like to make an impact on improving the quality of life of millions suffering from allergic diseases? Do you have mass spectrometry experience within proteomics and protein characterisation and would like to be part of a research department in constant development? Then this research scientist position is for you.
To strengthen the MS-based analytical platform, ALK is looking for a skilled and passionate mass spectrometrist to join our Mass Spectrometry and Proteomics team. The team is placed in Biotechnology Research and is involved in early discovery and characterisation of new potential leads, such as allergens/proteins, peptides, and small molecules, as well as supporting existing products and the ALK pipeline. Biotechnology Research characterises lead candidates by applying several analytical methods covering both general protein-chemical methods and more specialized analytical tools like MS. Your key scientific responsibility will be to develop mass spectrometry methods to support research in allergy specific immunotherapy and drug discovery. Further, your role will be to strengthen the Mass Spectrometry and Proteomics by contributing to current research activities and undoubtedly have a key role in making significant contributions to our research.
Fields of responsibility
Your qualifications
We offer
ALK provides a dynamic and pleasant work environment, complete with inspiring and challenging assignments. The results of your efforts will be significant throughout the organization, and you will be able to actively influence and challenge the status quo. Our flat structures attract independent individuals who like to feel the progress of the business and enjoy being close to the decision-making process. You will be part of an engaged and informal team who values skill and knowledge creation. We consider our pioneering spirit coupled with our trustworthiness our winning formula. ALK is a health focused organization, and our offices offer a green view of the DTU Science Park in Hørsholm.
Application deadline
22 April 2022
Contact
For further information on the position please contact Manager Kathrine Beck Sylvestersen +45 61 91 32 16.
To strengthen the MS-based analytical platform, ALK is looking for a skilled and passionate mass spectrometrist to join our Mass Spectrometry and Proteomics team. The team is placed in Biotechnology Research and is involved in early discovery and characterisation of new potential leads, such as allergens/proteins, peptides, and small molecules, as well as supporting existing products and the ALK pipeline. Biotechnology Research characterises lead candidates by applying several analytical methods covering both general protein-chemical methods and more specialized analytical tools like MS. Your key scientific responsibility will be to develop mass spectrometry methods to support research in allergy specific immunotherapy and drug discovery. Further, your role will be to strengthen the Mass Spectrometry and Proteomics by contributing to current research activities and undoubtedly have a key role in making significant contributions to our research.
Fields of responsibility
- Develop proteomic and mass spectrometry methods for identification and characterisation of proteins, peptides, process impurities, degradation products, or metabolites.
- Apply qualitative and quantitative LC-MS/MS analyses for quantification of proteins within complex mixtures (by absolute quantification, label-free and quantification with isobaric labels).
- Explore new opportunities to integrate MS based methodology within the field of allergy research and for characterisation of existing products.
- Maintain / troubleshoot LC-MS instrumentation.
- Collaborate cross-functionally with Contract Research Organisation or other departments and functions outside Global Research e.g., CMC Development, Production, Medical and Regulatory affairs.
- Participate in relevant international congresses, publish in international scientific journals, and actively contribute to patents and innovations.
Your qualifications
- Ph. D. in Protein chemistry/Biochemistry/Organic chemistry/Medicinal chemistry or related fields preferably with relevant postdoctoral training or industry experience.
- Strong background in theory and fundamentals of mass spectrometry and ionization methodologies.
- Extensive hands-on experience in characterisation and quantification of proteins, peptides, and natural product extracts by LC-MS/MS.
- Distinct major advantages would be hands on experience with intact protein MS analysis and/or knowledge within Hydrogen Deuterium Exchange (HDX) LC-MS.
- Additional advantageous would be experience within MS of small molecules and/or glycoproteomics.
- Experience in collaborating with various teams and Contract Research Organisation.
- Ability to work independently and with minimal supervision.
- Excellent oral and written communication skills; highly organized and efficient record keeping.
- You are scientifically curious, a natural team player and possess strong personal collaboration skills.
We offer
ALK provides a dynamic and pleasant work environment, complete with inspiring and challenging assignments. The results of your efforts will be significant throughout the organization, and you will be able to actively influence and challenge the status quo. Our flat structures attract independent individuals who like to feel the progress of the business and enjoy being close to the decision-making process. You will be part of an engaged and informal team who values skill and knowledge creation. We consider our pioneering spirit coupled with our trustworthiness our winning formula. ALK is a health focused organization, and our offices offer a green view of the DTU Science Park in Hørsholm.
Application deadline
22 April 2022
Contact
For further information on the position please contact Manager Kathrine Beck Sylvestersen +45 61 91 32 16.
Information og data
Denne ledige stilling har jobtypen "Forretningsudvikler", og befinder sig i kategorien "Kommunikation, marketing, salg".
Arbejdsstedet er beliggende i Hørsholm.
Jobbet er oprettet på vores service den 16.3.2022, men kan have været deaktiveret og genaktiveret igen.
Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
- Forretningsudvikler
- Hørsholm
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