Senior Pharmacology Scientist

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We are seeking a highly skilled and motivated Senior Scientist with significant expertise in preclinical studies in rodents to join the Rare Disease Pharmacology department with expected start May 1st, 2023, or soon thereafter. We offer a healthy and engaging work environment with an opportunity to contribute to a goal of improving the quality of life of people living with rare endocrine or rare blood disorders. Come and join us! The position You will be part of a dedicated in vivo pharmacology team in the Rare Disease Research area within Global Drug Discovery. You will implement disease models to study lysosomal storage disorders (LSDs) and establish relevant phenotypical tests. You will also design, execute, and report high-quality in vivo studies within LSDs and other rare disease areas. You will be involved in collaborative efforts to deliver in vivo support across the Rare Disease portfolio. You will interpret and report data for discussion in project groups and with internal / external stakeholders, provide input on in vitro/in vivo as well as preclinical/clinical translation, and support multidisciplinary drug discovery teams in Novo Nordisk. The successful candidate will participate hands-on in implementation of novel techniques in the laboratory. You will explore and characterise pharmacological efficacy of innovative candidate molecules within a broad spectrum of therapeutic modalities. You are expected to collaborate with other areas in Novo Nordisk, including our RNA and Gene Therapies teams and colleagues at our global research sites, as well as with external contractors and collaborators. Qualifications You hold a PhD and an MSc or equivalent within biological or biomedical science, veterinary medicine, medicine, human physiology or another relevant field. You have experience working with animals in a biotech- or industry setting and have a keen interest in that line of work. You are required to hold a FELASA accredited certificate corresponding to Laboratory Animal Science Function A/B/D (previously designated category C) according to the EU Directive 2010/63/EU Article 23.2. In addition, the candidates are expected to have:
  • Experience conducting animal pharmacology studies for research, including statistical design of experiments and statistical analysis of data, administration of test compounds etc. Experience working with pharmacology Contract Research Organizations would be a plus
  • Experience with designing preclinical pharmacokinetic studies to support efficacy- and safety studies etc.
  • Understanding of immunocytochemical-, histochemical- and immunohistochemical methods, including immunofluorescence assays for ex vivo analysis, such as image cytometry
  • Insights in pathology of lysosomal storage disorders including endo-lysosomal function, cellular lipid metabolism, and neurodegeneration
  • Experience with one or more lysosomal storage disorder and relevant disease models including clinical observation and examination, motor coordination and balance tests such as rotarod, gait analysis, and limb clasping test
  • Experience with project work within the pharmaceutical industry and value chain understanding, e.g., via work experience beyond research
    • In addition, excellent communication skills with a focus on scientific quality and thorough documentation. Proficiency in both spoken and written English is essential; skills in Danish or another Scandinavian language would be an advantage. On a personal level, you have good organizational skills, pay attention to details, and manage time well, enabling efficiency and independence. You are highly motivated, a good team player, and interact effectively with internal as well as external colleagues fostering a collaborative workplace environment. About the department Rare Disease Pharmacology is one of three departments in the Rare Disease Research area, an expanding new area where currently 45 scientists and technicians are investigating novel concepts and drug candidates to improve treatment for patients living with rare blood- or rare endocrine disease. In Rare Disease Pharmacology, we are deeply involved in discovery and characterisation of innovative drug candidates by in vivo and ex vivo studies, liaising with other areas of Novo Nordisk and also engaging with external experts. We are looking forward to getting new expertise and colleagues on board to join our journey! Working at Novo Nordisk At Novo Nordisk, we don't wait for change. We drive it. We're a dynamic company in an even more dynamic industry, and we know that what got us to where we are today is not necessarily what will make us successful in the future. We embrace the spirit of experimentation, striving for excellence without fixating on perfection. We never shy away from opportunities to develop, we seize them. From research and development, through to manufacturing, marketing, and sales - we're all working to raise the bar for patient care. Contact For further information, please contact Carsten Dan Ley at +45 3079 5168. Deadline 30 April 2023 Please note that applications will be assessed on an ongoing basis and therefore the advert may close before the recruitment process is completed if we have proceeded with candidates to the screening or interview phase. Please include some lines describing your motivation for this job in your resume or CV or attach a cover letter. In addition, please avoid the use of photos in your CV. This makes for a better and more fair process. We commit to an inclusive recruitment process and equality of opportunity for all our job applicants. At Novo Nordisk we recognize that it is no longer good enough to aspire to be the best company in the world. We need to aspire to be the best company for the world and we know that this is only possible with talented employees with diverse perspectives, backgrounds and cultures. We are therefore committed to creating an inclusive culture that celebrates the diversity of our employees, the patients we serve and communities we operate in. Together, we’re life changing.


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    Denne ledige stilling har jobtypen "Forretningsudvikler", og befinder sig i kategorien "Kommunikation, marketing, salg".

    Arbejdsstedet er beliggende i Måløv.

    Jobbet er oprettet på vores service den 20.4.2023, men kan have været deaktiveret og genaktiveret igen.

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