Computational Peptide Design Scientist
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Do you have strong knowledge and experience in computational peptide design methods? Would you like to work in a collaborative global Molecular AI team to invent novel medicines by applying and developing computational methods?
If so, apply today for a life-changing career! The Position
As a Computational Peptide Design Scientist, you will be an important team member of Molecular AI and contribute to the research team's effort towards exploring and creating new technology and continuing to be a world leader in peptide drug design. You will work closely with Research Chemistry to develop new technologies and design ultra-large peptide libraries.
You will report to the Associate Director of Molecular AI and will have close interactions with scientists and experts within Research Chemistry. Additional internal partners include data scientists, specialists, engineers, software developers, technology scouts & partnership developers, and others across US and Denmark. External relationships include commercial and academic collaboration partners.
Your key areas of responsibility will be to: Developing complex workflows to support the selection, design, and optimization of peptide modalities. Design and optimization of drug candidates using advanced computational techniques as a member of therapeutic project teams. Take initiative in recognizing and addressing unmet scientific needs using internal and external data and the desire to grow outside the comfort zone. Contribute to ongoing portfolio projects within multiple therapy areas. Analyse and conclude large datasets. Maintain a well-documented, reusable codebase, and traceable model history. Work closely with Therapeutic areas, Research Chemistry and Biophysics, and formulation teams to drive discovery and development efforts. Actively participates in cross-functional teams to develop AI and ML solutions. Qualifications
To succeed in this role, you have: Ph.D. with 0-2+ years’ relevant experience with peptide structure-based design methods using conformational analysis, amino acid monomers, in silico mutation, property prediction, or similar. Examples of your work, such as GitHub repositories or publications that can showcase your skill. Proficiency in Python (or another scientific programming), cheminformatics tools, and cloud computing to curate and analyze data at scale and implement new metrics to predict and select peptide designs. Proficiency with at least one modeling software package (e.g., Schrodinger, Rosetta, similar), or in general molecular modeling techniques (docking, molecular simulation, homology modeling, quantum mechanics, ligand- and structure-based design) Ability to perform in-depth data analysis and present results and conclusions to engineering and leadership teams. Preferred experience and skills include: Research experience related to ultra large library design. Experience with macrocyclic design – highly preferred. Experience with QSAR, machine learning, deep learning. •Drug discovery experience in the field of peptide therapeutics within industry or academics.
About the Department
The Molecular AI team is part of Novo Nordisk’s Computational Drug Design (CDD) area where we apply and develop state of the art capabilities in predictive science, AI/ML and structure-based drug design. Scientists within CDD collaborate seamlessly with teams across the globe to invent better molecules faster. With an unbiased approach to drug modalities, in-house access to the newest screening techniques, and world-class experimentation, we have a wealth of opportunities to impact our pipeline and ultimately save and improve patient lives. We work in multidisciplinary, highly collaborative discovery teams both locally and across Novo Nordisk’s global network to invent novel medicines by applying advanced computational techniques and developing innovative computational methods. We engage in external collaborations to ensure access to cutting edge research and technology. Molecular AI is working to establish ourselves as global leaders in the research, development, and application of small molecule, peptides, and RNA. We support cutting-edge research projects and develop innovative technologies in this field. We foster strong collaborations with Research Chemistry within our Global Research and Technology (GRT) organization and the Dicerna Transformational Research Unit (TRU). With a team of scientists located in both Denmark and the United States, we strive to deliver the latest advancements in small molecules, peptides, and RNA to benefit patient health and global medicine.
Working at Novo Nordisk
At Novo Nordisk, we don’t wait for change. We drive it. We’re a dynamic company in an even more dynamic industry, and we know that what got us to where we are today is not necessarily what will make us successful in the future. We embrace the spirit of experimentation, striving for excellence without fixating on perfection. We never shy away from opportunities to develop, we seize them. From research and development, through to manufacturing, marketing and sales – we’re all working to move the needle on patient care. Contact
Do you have questions regarding the role? Then please contact the Associate Director of Molecular AI, Kristine Deibler via email: [email protected]
Please apply directly through the career page, as we are not able to review candidates sharing their CVs by e-mail or other channels. You do not need to attach a cover letter to your application, but please include a few sentences about why you are applying in your resume or CV. To ensure an efficient and fair recruitment process, please refrain from adding a photo in your CV.
We commit to an inclusive recruitment process and equality of opportunity for all our job applicants. At Novo Nordisk we recognize that it is no longer good enough to aspire to be the best company in the world. We need to aspire to be the best company for the world and we know that this is only possible with talented employees with diverse perspectives, backgrounds and cultures. We are therefore committed to creating an inclusive culture that celebrates the diversity of our employees, the patients we serve and communities we operate in. Together, we’re life changing.
If so, apply today for a life-changing career! The Position
As a Computational Peptide Design Scientist, you will be an important team member of Molecular AI and contribute to the research team's effort towards exploring and creating new technology and continuing to be a world leader in peptide drug design. You will work closely with Research Chemistry to develop new technologies and design ultra-large peptide libraries.
You will report to the Associate Director of Molecular AI and will have close interactions with scientists and experts within Research Chemistry. Additional internal partners include data scientists, specialists, engineers, software developers, technology scouts & partnership developers, and others across US and Denmark. External relationships include commercial and academic collaboration partners.
Your key areas of responsibility will be to:
To succeed in this role, you have:
About the Department
The Molecular AI team is part of Novo Nordisk’s Computational Drug Design (CDD) area where we apply and develop state of the art capabilities in predictive science, AI/ML and structure-based drug design. Scientists within CDD collaborate seamlessly with teams across the globe to invent better molecules faster. With an unbiased approach to drug modalities, in-house access to the newest screening techniques, and world-class experimentation, we have a wealth of opportunities to impact our pipeline and ultimately save and improve patient lives. We work in multidisciplinary, highly collaborative discovery teams both locally and across Novo Nordisk’s global network to invent novel medicines by applying advanced computational techniques and developing innovative computational methods. We engage in external collaborations to ensure access to cutting edge research and technology. Molecular AI is working to establish ourselves as global leaders in the research, development, and application of small molecule, peptides, and RNA. We support cutting-edge research projects and develop innovative technologies in this field. We foster strong collaborations with Research Chemistry within our Global Research and Technology (GRT) organization and the Dicerna Transformational Research Unit (TRU). With a team of scientists located in both Denmark and the United States, we strive to deliver the latest advancements in small molecules, peptides, and RNA to benefit patient health and global medicine.
Working at Novo Nordisk
At Novo Nordisk, we don’t wait for change. We drive it. We’re a dynamic company in an even more dynamic industry, and we know that what got us to where we are today is not necessarily what will make us successful in the future. We embrace the spirit of experimentation, striving for excellence without fixating on perfection. We never shy away from opportunities to develop, we seize them. From research and development, through to manufacturing, marketing and sales – we’re all working to move the needle on patient care. Contact
Do you have questions regarding the role? Then please contact the Associate Director of Molecular AI, Kristine Deibler via email: [email protected]
Please apply directly through the career page, as we are not able to review candidates sharing their CVs by e-mail or other channels. You do not need to attach a cover letter to your application, but please include a few sentences about why you are applying in your resume or CV. To ensure an efficient and fair recruitment process, please refrain from adding a photo in your CV.
We commit to an inclusive recruitment process and equality of opportunity for all our job applicants. At Novo Nordisk we recognize that it is no longer good enough to aspire to be the best company in the world. We need to aspire to be the best company for the world and we know that this is only possible with talented employees with diverse perspectives, backgrounds and cultures. We are therefore committed to creating an inclusive culture that celebrates the diversity of our employees, the patients we serve and communities we operate in. Together, we’re life changing.
Information og data
Denne ledige stilling har jobtypen "Forretningsudvikler", og befinder sig i kategorien "Kommunikation, marketing, salg".
Arbejdsstedet er beliggende i Måløv.
Jobbet er oprettet på vores service den 21.4.2023, men kan have været deaktiveret og genaktiveret igen.
Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
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