Scientist/Sr. Scientist - Neuroimmunology

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Dragonfly Therapeutics is seeking a highly motivated and experienced scientist with a strong focus on human and mouse in vitro models of multiple sclerosis and Alzheimer’s disease to join Dragonfly’s Inflammation Biology team in Copenhagen- Denmark.

The successful candidate will be responsible for setting up in vitro models of multiple sclerosis and Alzheimer’s disease and developing assays to test our drug candidates. The work will include isolation and culture of primary immune cells such as NK cells, microglia, and macrophages isolated from human samples (e.g., blood, CSF, and brain tissues) as well as from animals. Expert knowledge in microglial cell biology is highly desired. This position also requires that the candidate be proficient with immunological assays and technologies such as multi-color flow cytometry, cell-based functional assays, cellular imaging, ELISA/Luminex, and histology. The candidate will participate in cross-functional efforts to progress our drug candidates and take responsibility for the design and conduct of relevant in vitro models to support the projects.

Responsibilities:

  • Design and perform in vitro studies relevant for multiple sclerosis and Alzheimer’s disease
  • Isolate, culture, and set up functional assays using human microglia cells and NK cells
  • Analyze, interpretate and report results from the studies in a timely manner
  • Train research associates and principal laboratory technicians with hands-on work on human in vitro assays
  • Interface with CROs for histological analysis and vendors for acquisition of relevant materials and reagents
  • Generate, manage, analyze, and maintain critical data with integrity and in a highly organized manner

Qualifications:

  • Ph.D. with extensive experience in neurodegenerative diseases
  • A deep understanding of the pathology of Alzheimer’s disease and multiple sclerosis
  • Experience in AD animal models is preferred
  • Hands-on experience with standard immunology techniques including flow cytometry, ELISA, phagocytosis and cytotoxicity assays, cellular imaging and flow cytometry is required
  • Experience working with CROs and vendors
  • Efficient time management and ability to work on several projects simultaneously
  • Strong interpersonal skills and ability to effectively communicate with members of a multidisciplinary team
  • Ability to work collaboratively, provide scientific insight, and communicate clearly in writing and orally is critical for success in this position
  • Excellent record keeping abilities to document analytical data generated in support of regulatory requirements, experience with ELN
  • A flexible mindset with the ability to adapt to a rapidly changing environment in a fast-growing start-up.

About Dragonfly

Founded in 2015 by Dr. Tyler Jacks, head of the Koch Institute at MIT, Dr. David Raulet, one of the world's leading experts in Natural Killer (NK) cell biology, and Bill Haney, a longtime tech entrepreneur and investor, Dragonfly Therapeutics was launched to harness the power of the immune system to provide breakthrough treatments for patients – especially in areas where there are no effective treatments, today.

The company develops novel first-in-class therapeutics designed to harness Natural Killer cells and other cells of the innate immune system which can provide direct killing of disease promoting cell types and provide a unique therapeutic window beyond current therapies for treatment of cancer and chronic inflammatory diseases.

Our mission is to revolutionize disease treatment by inventing natural killer cell-based therapies for vastly improved patient outcomes. We believe in a small team with a big impact.

Your application

Please apply by sending a cover letter and resume as soon as possible through the button "Apply / Send ansøgning". We are screening and interviewing for the position on an ongoing basis. For any further questions please contact: [email protected]


For more info, check out our career site https://dragonflytx.ofir.com



Denne jobannonce blev oprindeligt opslået på https://www.ofir.dk/
(Den originale annonce kan ses på: https://www.ofir.dk/showojob?ofirid=bd19ab2c)
Kilde: Jobnet.dk


Information og data

Denne ledige stilling har jobtypen "Forsker", og befinder sig i kategorien "Sundhed og forskning".

Arbejdsstedet er beliggende i Ballerup.

Jobbet er oprettet på vores service den 5.3.2021, men kan have været deaktiveret og genaktiveret igen.

Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
  • Forsker
  • Ballerup
  • Fredag den 09. april 2021

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