Research scientist for LC-MS bioanalysis and pharmacokinetics
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Hørsholm
Gubra is looking for a bioanalysis scientist to support our contract research organization (CRO) and drug discovery projects. In this role you will use LC-MS to quantify drugs (small molecules and peptides), metabolites and biomarkers in tissue, blood, and plasma from our studies in rodents and minipigs.
The Drug Profiling department supports the Gubra CRO with bioanalysis for in vivo pharmacology experiments. Furthermore, we support internal drug discovery & development projects by delivering physicochemical characterization, early formulation development, analytical support, and PKPD analysis for novel peptide drug candidates. We are currently 5 scientists and 4 laboratory technicians in the department.
You have a strong interest in ESI-LC-MS(MS) analysis of peptides and small molecules. You are technologically savvy, inventive, and flexible and you value collaboration with your skilled colleagues. You take pride and ownership for delivering high quality data, are organized and thrive when working independently.
As bioanalysis scientist in Drug Profiling, your tasks will include:
Professional qualifications
As a person you are
Please apply no later than April 8th, 2024, by uploading your motivated cover letter, resume and relevant diplomas on our website. We will invite candidates for interviews continuously, so we look forward to hearing from you as soon as possible. If we find the right candidate, we will close the job before the deadline. If you have questions about the position, please contact Department Manager Jakob Plum Christensen at [email protected] or phone +45 22 93 57 84.
About Gubra
Gubrais an ambitious contract research organisation (CRO) and biotech company striving for excellence at all levels. We insist on doing things efficiently – and often differently - to reach the results we aim for. Our vision is to become leaders in the fight for a more sustainable and healthier world. We do that by facilitating the discovery of new medicine, and by acting and inspiring others to fight the ongoing climate and biodiversity crises.
Gubra’s activities are focused on the early stages of drug development and are organised in two highly synergistic business areas: CRO Services and Discovery & Partnerships (D&P). We generate our revenue by performing research for life science companies as well as by partnering projects from our discovery and development pipeline.
Our therapeutic focus is within metabolic and fibrotic diseases, and we specialize in in vivo pharmacology, ex vivo assays, drug profiling, histology, stereology and whole brain and organ imaging. In addition, we offer a full palette of advanced transcriptomics. Our ML/AI-driven peptide drug discovery platform streaMLine enables us to rapidly develop a peptide hit into a non-clinical candidate ready for development. Through a constant focus on high quality, scientific excellence, speed, and solid teamwork we have established ourselves as a highly professional and competent partner in the market.
People are our greatest asset, and our team consists of +220 employees all located in Hørsholm, Denmark. The mix of people from different cultures and educational backgrounds combined with our entrepreneurial mindset have greatly impacted our working environment, which is characterized by entrepreneurial drive, scientific curiosity, and teamwork – we join forces!
The Drug Profiling department supports the Gubra CRO with bioanalysis for in vivo pharmacology experiments. Furthermore, we support internal drug discovery & development projects by delivering physicochemical characterization, early formulation development, analytical support, and PKPD analysis for novel peptide drug candidates. We are currently 5 scientists and 4 laboratory technicians in the department.
You have a strong interest in ESI-LC-MS(MS) analysis of peptides and small molecules. You are technologically savvy, inventive, and flexible and you value collaboration with your skilled colleagues. You take pride and ownership for delivering high quality data, are organized and thrive when working independently.
As bioanalysis scientist in Drug Profiling, your tasks will include:
- LC-MS method development for small molecules and peptides
- Sample preparation and analysis of plasma and tissue samples
- Quantification of analytes by SRM using ESI-LC-MS(MS) and quality assessment
- Delivery of drug exposure and pharmacokinetics data to CRO costumers, internal and partnered projects
- Stakeholder management and day-to-day planning and guidance of laboratory tasks
- Troubleshooting and maintenance of equipment and performance monitoring
Professional qualifications
- PhD or M.Sc. with 1-2 years relevant experience in bioanalytical chemistry/biochemistry
- Hands-on experience with plasma bioanalysis, LC-MS and assay optimisation
- Quality conscious and organized
- A desire to develop as an expert in LC-MS
As a person you are
- Keen to take on responsibility
- Focused on delivering outstanding service
- A true team player and eager to contribute to all workflows in the department
- Proactive and able to initiate, focus and deliver on tasks and projects
- Able to navigate and collaborate in an energetic and rapidly changing organization
Please apply no later than April 8th, 2024, by uploading your motivated cover letter, resume and relevant diplomas on our website. We will invite candidates for interviews continuously, so we look forward to hearing from you as soon as possible. If we find the right candidate, we will close the job before the deadline. If you have questions about the position, please contact Department Manager Jakob Plum Christensen at [email protected] or phone +45 22 93 57 84.
About Gubra
Gubrais an ambitious contract research organisation (CRO) and biotech company striving for excellence at all levels. We insist on doing things efficiently – and often differently - to reach the results we aim for. Our vision is to become leaders in the fight for a more sustainable and healthier world. We do that by facilitating the discovery of new medicine, and by acting and inspiring others to fight the ongoing climate and biodiversity crises.
Gubra’s activities are focused on the early stages of drug development and are organised in two highly synergistic business areas: CRO Services and Discovery & Partnerships (D&P). We generate our revenue by performing research for life science companies as well as by partnering projects from our discovery and development pipeline.
Our therapeutic focus is within metabolic and fibrotic diseases, and we specialize in in vivo pharmacology, ex vivo assays, drug profiling, histology, stereology and whole brain and organ imaging. In addition, we offer a full palette of advanced transcriptomics. Our ML/AI-driven peptide drug discovery platform streaMLine enables us to rapidly develop a peptide hit into a non-clinical candidate ready for development. Through a constant focus on high quality, scientific excellence, speed, and solid teamwork we have established ourselves as a highly professional and competent partner in the market.
People are our greatest asset, and our team consists of +220 employees all located in Hørsholm, Denmark. The mix of people from different cultures and educational backgrounds combined with our entrepreneurial mindset have greatly impacted our working environment, which is characterized by entrepreneurial drive, scientific curiosity, and teamwork – we join forces!
Information og data
Denne ledige stilling har jobtypen "Forsker", og befinder sig i kategorien "Sundhed og forskning".
Arbejdsstedet er beliggende i Hørsholm.
Jobbet er oprettet på vores service den 18.3.2024, men kan have været deaktiveret og genaktiveret igen.
Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
- Forsker
- Hørsholm
- Mandag den 08. april 2024
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