Experienced DMPK Scientist with broad reach in Drug Discovery/Early Development
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Hørsholm
Are you eager to design and shape the future peptide DMPK workflows at Gubra?
Do you want to take on the role as DMPK scientist for a dynamic TechBio company with a highly cross-organizational and entrepreneurial setup? At Gubra, you will see your efforts turn into tangible projects, partnerships and results. And you will do so in a fantastic environment where everyone is eager to help and drive things forward.
Broad reach from Early Drug Discovery to Early Drug Development.
As a DMPK Scientist, your focus will be on evaluating peptide candidates in a range of in vitro, ex vivo and in vivo assays spanning from early drug discovery to First In Human (FIH) studies.
You will be part of the bioanalysis team, currently consisting of 3 scientists and 2 laboratory technicians, within the Drug Profiling department.
You will unfold your skills as part of project teams alongside specialist colleagues in computational drug discovery, peptide chemistry, molecular pharmacology, drug profiling, formulation and in vivo pharmacology. This also covers your close collaboration with your dedicated laboratory technician colleagues who are eager to continuously improve our workflows.
Your primary tasks will include:
PhD within pharmaceutical sciences and industry DMPK experience
As you will be part of an organization whose success rests on knowledge sharing and cross-organizational collaboration, you must be comfortable sharing your early-stage ideas as well as receiving and providing constructive feedback. Equally important is your ability to thrive in an ever-evolving organization, where new strategies, new technologies, new ways of working are part of daily life at Gubra. Additionally, your resume comprises:
Contact and application
We encourage you to submit your application as soon as possible, as we will be reviewing applications on an ongoing basis. Please apply no later than March 20, 2025 by uploading your motivated cover letter, resume and relevant diplomas on our website.
If you have any questions, you are very welcome to contact Senior Department Manager, Jakob Plum Christensen at
We are looking forward to receiving your application.
About Gubra
is an ambitious contract research organisation (CRO) and biotech company striving for excellence at all levels. We insist on doing things efficiently – and often differently - to achieve the results we aim for. Our vision is to become leaders in the fight for a healthier and more sustainable world. We do that by facilitating the discovery of new medicine, and by acting and inspiring others to fight the ongoing climate and biodiversity crises.
Gubra’s activities are focused on the early stages of drug development and are organised in two highly synergistic business areas: CRO Services and Discovery & Partnerships (D&P). We generate our revenue by performing research for life science companies as well as by partnering projects from our discovery and development pipeline.
Our therapeutic focus is within metabolic and fibrotic diseases, and we specialize in in vivo pharmacology, ex vivo assays, drug profiling, histology, stereology and whole brain and organ imaging. In addition, we offer a full palette of advanced transcriptomics. Our ML/AI-driven peptide drug discovery platform streaMLine enables us to rapidly develop a peptide hit into a non-clinical candidate ready for development. Through a constant focus on high quality, scientific excellence, speed, and solid teamwork we have established ourselves as a highly professional and competent partner in the market.
People are our greatest asset, and our team consists of +260 employees all located in Hørsholm, Denmark. The mix of people from different cultures and educational backgrounds combined with our entrepreneurial mindset have greatly impacted our working environment, which is characterized by entrepreneurial drive, scientific curiosity, and teamwork – we join forces!
Check out more inspiration.
Do you want to take on the role as DMPK scientist for a dynamic TechBio company with a highly cross-organizational and entrepreneurial setup? At Gubra, you will see your efforts turn into tangible projects, partnerships and results. And you will do so in a fantastic environment where everyone is eager to help and drive things forward.
Broad reach from Early Drug Discovery to Early Drug Development.
As a DMPK Scientist, your focus will be on evaluating peptide candidates in a range of in vitro, ex vivo and in vivo assays spanning from early drug discovery to First In Human (FIH) studies.
You will be part of the bioanalysis team, currently consisting of 3 scientists and 2 laboratory technicians, within the Drug Profiling department.
You will unfold your skills as part of project teams alongside specialist colleagues in computational drug discovery, peptide chemistry, molecular pharmacology, drug profiling, formulation and in vivo pharmacology. This also covers your close collaboration with your dedicated laboratory technician colleagues who are eager to continuously improve our workflows.
Your primary tasks will include:
- Serving as DMPK lead in drug discovery projects
- Apply PK/PD modelling and simulations to guide project decisions.
- Shaping and developing Gubra’s peptide DMPK workflow
- Designing, developing, optimizing and analyzing in vitro, ex vivo and in vivo ADME & PK/PD studies
- Communicating results and discussing new findings
- Collaborating with laboratory technicians to conduct LCMS-based bioanalysis
PhD within pharmaceutical sciences and industry DMPK experience
As you will be part of an organization whose success rests on knowledge sharing and cross-organizational collaboration, you must be comfortable sharing your early-stage ideas as well as receiving and providing constructive feedback. Equally important is your ability to thrive in an ever-evolving organization, where new strategies, new technologies, new ways of working are part of daily life at Gubra. Additionally, your resume comprises:
- PhD with 5+ years’ experience within DMPK
- Hands-on experience with PK/PD modelling using Phoenix, R, NONMEM or similar
- Hands-on experience with LCMS based bioanalysis & data analysis
- Experience with in vitro and ex vivo DMPK assays, such as plasma stability
- Experience with preclinical translation and FIH dose setting
- Motivation to integrate AI and ML into the workflow – prior AI/ML experience is a plus but not required
- An innovative and collaborative mindset
Contact and application
We encourage you to submit your application as soon as possible, as we will be reviewing applications on an ongoing basis. Please apply no later than March 20, 2025 by uploading your motivated cover letter, resume and relevant diplomas on our website.
If you have any questions, you are very welcome to contact Senior Department Manager, Jakob Plum Christensen at
We are looking forward to receiving your application.
About Gubra
is an ambitious contract research organisation (CRO) and biotech company striving for excellence at all levels. We insist on doing things efficiently – and often differently - to achieve the results we aim for. Our vision is to become leaders in the fight for a healthier and more sustainable world. We do that by facilitating the discovery of new medicine, and by acting and inspiring others to fight the ongoing climate and biodiversity crises.
Gubra’s activities are focused on the early stages of drug development and are organised in two highly synergistic business areas: CRO Services and Discovery & Partnerships (D&P). We generate our revenue by performing research for life science companies as well as by partnering projects from our discovery and development pipeline.
Our therapeutic focus is within metabolic and fibrotic diseases, and we specialize in in vivo pharmacology, ex vivo assays, drug profiling, histology, stereology and whole brain and organ imaging. In addition, we offer a full palette of advanced transcriptomics. Our ML/AI-driven peptide drug discovery platform streaMLine enables us to rapidly develop a peptide hit into a non-clinical candidate ready for development. Through a constant focus on high quality, scientific excellence, speed, and solid teamwork we have established ourselves as a highly professional and competent partner in the market.
People are our greatest asset, and our team consists of +260 employees all located in Hørsholm, Denmark. The mix of people from different cultures and educational backgrounds combined with our entrepreneurial mindset have greatly impacted our working environment, which is characterized by entrepreneurial drive, scientific curiosity, and teamwork – we join forces!
Check out more inspiration.
Information og data
Denne ledige stilling har jobtypen "Forsker", og befinder sig i kategorien "Sundhed og forskning".
Arbejdsstedet er beliggende i Hørsholm.
Jobbet er oprettet på vores service den 28.2.2025, men kan have været deaktiveret og genaktiveret igen.
Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
- Forsker
- Hørsholm
- Torsdag den 20. marts 2025
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