PhD fellowship in Metabolic Genomics

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København N

Novo Nordisk Foundation Center for Basic Metabolic Research
University of Copenhagen


We are offering a PhD fellowship in Metabolic Genomics commencing February 1, 2022, or after agreement.

Our group and research:
The Novo Nordisk Foundation Center for Basic Metabolic Research’s vision is to strengthen interdisciplinary research that transforms our basic understanding of the mechanisms that underlie metabolic health and disease, and to accelerate this knowledge toward new prevention and treatment strategies. We were established in 2010 and in 2017, we moved into new laboratories, offices and meeting rooms in the Maersk Tower www.maersktower.ku.dk.

The Center has around 260 employees who work in an international, highly collaborative research environment across a range of biomedical disciplines. You can read more about us here: www.cbmr.ku.dk.

The Group:
The Pers Group investigates molecular processes driving susceptibility to obesity and type 2 diabetes with a particular focus on identifying and characterize molecular pathways exhibiting sustained effects on metabolic health. Their vision is to generate scientific knowledge that can accelerate more effective prevention and treatment of these two diseases. More information about the group can be found here.

Project description:
We seek an enthusiastic, passionate researcher to perform a PhD project in metabolic genomics and data science. The main objective of the PhD project is to identify candidate causal enhancers, gene regulatory networks and effector genes regulating energy homeostasis. The project will involve analysis of multimodal single-cell RNA- and chromatin accessibility data, analysis of genetic CRISPR/Cas9 perturbation data and modelling of enhancer to gene mapping. The successful applicant will apply these techniques on human post-mortem brain and rodent brain samples and work in an interdisciplinary team comprising molecular biologists, mathematicians and computational biologists.

Principal supervisor is Associate Professor Tune H. Pers, Novo Nordisk Foundation Center for Basic Metabolic Research, E-mail: [email protected]

Start: February 1, 2022 or after agreement
Duration: 3 years as a PhD student

Job description:
Your key tasks as a PhD student at SUND are:

  • Carry through an independent research project under supervision
  • Complete PhD courses or other equivalent education corresponding to approx. 30 ECTS points
  • Participate in active research environments including a stay at another research team
  • Obtain experience with teaching or other types of dissemination related to your PhD project
  • Teach and disseminate your knowledge
  • Write a PhD thesis on the grounds of your project

Key criteria for the assessment of applicants:
Applicants must have qualifications corresponding to a master’s degree related to the subject area of the project e.g. molecular biology, molecular biomedicine, biochemistry, medicine, bioinformatics or biotechnology etc.

Other important criteria are:

  • Achievement of top grades in a molecular biology master’s degree.
  • A degree in mathematics or substantial coursework amount to at least 2-y curriculum.
  • Completion of courses in applied and theoretical statistics.
  • Pronounced experience in programming languages R and python.
  • Prior experience in working with deep learning techniques, ideally tensorFlow.
  • Prior experience in working with single-cell data.
  • Prior experience in working with enhancer-to-gene-mapping modeling.
  • Excellent written and spoken English language skills.

Place of employment
The place of employment is at the Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories, bioinformatics and statistic guidance, and access to big data from multiple cohorts.

Terms of employment
The employment as PhD fellow is full time and for 3 years. The starting date is February 1, 2022, or after agreement.
It is conditioned upon the applicant’s successful enrolment as a PhD student at the Graduate School at the Faculty of Health and Medical Sciences, University of Copenhagen. This requires submission and acceptance of an application for the specific project formulated by the applicant

The PhD study must be completed in accordance with The Ministerial Order on the PhD programme (2013) and the Faculty’s rules on achieving the degree. Salary, pension and terms of employment are in accordance with the agreement between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State. Depending on seniority, the monthly salary begins around 27.788 DKK /approx. 3.700 EUR (April 2021-level) plus pension.

Questions
For specific information about the PhD fellowship, please contact the principal supervisor.
General information about PhD study at the Faculty of Health and Medical Sciences is available at the Graduate School’s website: https://healthsciences.ku.dk/phd/guidelines/

Application procedure
Your application must be submitted electronically by clicking ‘Apply now’ below. The application must include the following documents in PDF format:

  1. Motivated letter of application (max. one page)
  2. CV incl. education, experience, language skills and other skills relevant for the position
  3. Certified copy of original Master of Science diploma and transcript of records in the original language, including an authorized English translation if issued in other language than English or Danish. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor is accepted.
    As a prerequisite for a PhD fellowship employment, your master’s degree must be equivalent to a Danish master’s degree. We encourage you to read more in the assessment database: https://ufm.dk/en/education/recognition-and-transparency/find-assessments/assessment-database. Please note that we might ask you to obtain an assessment of your education performed by the Ministry of Higher Education and Science
  4. Publication list (if possible)

Application deadline: 22 September 2021, 23.59pm CET

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor.

The assessor makes a non-prioritized assessment of the academic qualifications and experience with respect to the above-mentioned area of research, techniques, skills and other requirements listed in the advertisement.
Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

The University of Copenhagen wishes to reflect the diversity of society and welcome applications from all qualified candidates regardless of personal background.

Kilde: Jobnet.dk


Information og data

Denne ledige stilling har jobtypen "Forsker", og befinder sig i kategorien "Sundhed og forskning".

Arbejdsstedet er beliggende i København N.

Jobbet er oprettet på vores service den 26.8.2021, men kan have været deaktiveret og genaktiveret igen.

Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
  • Forsker
  • København N
  • Onsdag den 22. september 2021

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