Postdoc in Mucosal Immunology at the Department of Immunology and Microbiology
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København N
We are looking for a highly motivated and dynamic postdoc for a 3 year position to commence January 1st 2024 (or as close as possible to this date) to join the Mucosal Immunology Group headed by Professor William Agace at the Department of Immunology and Microbiology, Copenhagen University.
Information on the department can be found at: https://sic.ku.dk/
Our research
The successful candidate will join a superb team of international researchers within the newly established NovoNordisk Foundation challenge grant-funded ‘Center for Intestinal Immune Regulation (CIIR)’. CIIR comprises of 4 collaborating teams (Agace, CU; K. McCoy, Calgary (Canada); F. Bendtsen, Hvidovre hospital; L. Rønn-Larsen, DTU) whose combined expertise in mucosal immunology, gastroenterology, microbiota-host interactions, bioinformatics and state-of-the-art animal models aims to identify intestinal immune-stromal interactions important in intestinal homeostasis and in inflammatory bowel disease (IBD). In joining you will be part of a highly vibrant and cross-disciplinary team of researchers at the international forefront of mucosal immunology research.
Your job
Your project is to assess the role of environmental perturbations (dietary, antibiotic, antifungal, infection) on stromal cell subset development and immune function within the intestinal mucosa. For this you will utilize various state-of-the-art animal models and transgenic mice in combination with single cell RNA-seq, CITE-seq, and spatial proteomics/transcriptomics analysis as well as in vitro co-culture techniques to study intestinal stromal-immune interactions and downstream consequences of environmental perturbation on intestinal homeostasis and disease. The project is multi-disciplinary and will involve close collaborations with participating bioinformaticians as well as researchers analyzing human intestinal immune compartments in health and IBD. The work is also expected to include some teaching and/or supervision of students within the laboratory.
You must hold a PhD degree or equivalent in immunology, be highly motivated, have the ability to work independently but also enjoy contributing and working within a team. The successful candidates will have documented experience in mucosal immunology, working with transgenic animal models, mouse colony maintenance and in-depth analysis of murine intestinal tissues including cell isolation, multi-color flow cytometry and cell sorting and intestinal disease models. Additional experience with spatial transcriptomics/proteomics scRNA-seq and organ cultures will be considered a merit.
Profile
We are looking for a highly motivated and enthusiastic scientist with the following competencies and experience:
Essential experience and skills:
Desirable experience and skills:
Place of employment
The place of employment is at the Department of Immunology and Microbiology, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and all state-of-the-art equipment required for the project.
Terms of employment
The average weekly working hours are 37 hours per week.
The position is a fixed-term position limited to a period of 3years. The starting date is Jan 1st 2024 or after agreement.
Salary, pension and other conditions of employment are set in accordance with the Agreement between the Ministry of Taxation and AC (Danish Confederation of Professional Associations) or other relevant organisation. Currently, the monthly salary starts at 35,000 DKK/approx. 4,700 EUR (October 2021 level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.
Foreign and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.
The position is covered by the Job Structure for Academic Staff at Universities 2020.
Questions
For further information please contact William Agace-[email protected]
Foreign applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).
Application procedure
Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:
Deadline for applications: 3 October 2023. 23.59pm CET
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.
You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/
The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.
The University of Copenhagen wish to reflect the diversity of society and encourage all qualified candidates to apply regardless of personal background.
Kilde: Jobnet.dk
Information on the department can be found at: https://sic.ku.dk/
Our research
The successful candidate will join a superb team of international researchers within the newly established NovoNordisk Foundation challenge grant-funded ‘Center for Intestinal Immune Regulation (CIIR)’. CIIR comprises of 4 collaborating teams (Agace, CU; K. McCoy, Calgary (Canada); F. Bendtsen, Hvidovre hospital; L. Rønn-Larsen, DTU) whose combined expertise in mucosal immunology, gastroenterology, microbiota-host interactions, bioinformatics and state-of-the-art animal models aims to identify intestinal immune-stromal interactions important in intestinal homeostasis and in inflammatory bowel disease (IBD). In joining you will be part of a highly vibrant and cross-disciplinary team of researchers at the international forefront of mucosal immunology research.
Your job
Your project is to assess the role of environmental perturbations (dietary, antibiotic, antifungal, infection) on stromal cell subset development and immune function within the intestinal mucosa. For this you will utilize various state-of-the-art animal models and transgenic mice in combination with single cell RNA-seq, CITE-seq, and spatial proteomics/transcriptomics analysis as well as in vitro co-culture techniques to study intestinal stromal-immune interactions and downstream consequences of environmental perturbation on intestinal homeostasis and disease. The project is multi-disciplinary and will involve close collaborations with participating bioinformaticians as well as researchers analyzing human intestinal immune compartments in health and IBD. The work is also expected to include some teaching and/or supervision of students within the laboratory.
You must hold a PhD degree or equivalent in immunology, be highly motivated, have the ability to work independently but also enjoy contributing and working within a team. The successful candidates will have documented experience in mucosal immunology, working with transgenic animal models, mouse colony maintenance and in-depth analysis of murine intestinal tissues including cell isolation, multi-color flow cytometry and cell sorting and intestinal disease models. Additional experience with spatial transcriptomics/proteomics scRNA-seq and organ cultures will be considered a merit.
Profile
We are looking for a highly motivated and enthusiastic scientist with the following competencies and experience:
Essential experience and skills:
- You have a PhD in Immunology
- You have extensive experience in mouse models assessing intestinal bacterial and fungal interactions with the host
- You have extensive experience in the isolation and digestion of murine tissues (including intestine, mesenteric lymph nodes) as well as cell isolation and phenotypic analysis.
- You have extensive experience in flow cytometry (both conventional and spectral)
- Proficient communication skills and ability to work in teams
- Excellent English skills written and spoken
Desirable experience and skills:
- You have experience in microbiome (bacterial and fungal) analysis
- You have experience in molecular cell culture and
- You have some experience in the preparation and analysis of metabolmics samples
Place of employment
The place of employment is at the Department of Immunology and Microbiology, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and all state-of-the-art equipment required for the project.
Terms of employment
The average weekly working hours are 37 hours per week.
The position is a fixed-term position limited to a period of 3years. The starting date is Jan 1st 2024 or after agreement.
Salary, pension and other conditions of employment are set in accordance with the Agreement between the Ministry of Taxation and AC (Danish Confederation of Professional Associations) or other relevant organisation. Currently, the monthly salary starts at 35,000 DKK/approx. 4,700 EUR (October 2021 level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.
Foreign and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.
The position is covered by the Job Structure for Academic Staff at Universities 2020.
Questions
For further information please contact William Agace-[email protected]
Foreign applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).
Application procedure
Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:
- Motivated letter of application (max. one page).
- CV incl. education, work/research experience, language skills and other skills relevant for the position.
- A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.
- List of publications.
Deadline for applications: 3 October 2023. 23.59pm CET
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.
You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/
The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.
The University of Copenhagen wish to reflect the diversity of society and encourage all qualified candidates to apply regardless of personal background.
Kilde: Jobnet.dk
Information og data
Denne ledige stilling har jobtypen "Forsker", og befinder sig i kategorien "Sundhed og forskning".
Arbejdsstedet er beliggende i København N.
Jobbet er oprettet på vores service den 14.9.2023, men kan have været deaktiveret og genaktiveret igen.
Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
- Forsker
- København N
- Tirsdag den 03. oktober 2023
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