Postdoc position for human metabolic cell biologist
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København N
We are looking for a highly motivated postdoc with experience in working with human in vitro models, to start January 15, 2024, or after agreement.
Background
Our researchers share a common purpose as they seek to transform the basic understanding of the mechanisms involved in cardiometabolic health and disease, and to accelerate this knowledge towards new prevention and treatment strategies.
The Center has around 260 employees, spread across 22 research groups and 5 technology platforms, who work in a vibrant international research environment with a strong focus on interdisciplinary collaboration.
The Center’s research has resulted in seminal discoveries as to how genes, hormones, and environmental factors influence metabolic health and disease throughout life. You can read more about CBMR at www.cbmr.ku.dk.
Our group and research
The position available is in the Translational Cell Metabolism Group headed by Associate Professor Camilla Schéele. The research group studies human adipose tissue crosstalk. Major focus areas include human adipose tissue heterogeneity, brown fat recruitment and how secreted factors from brown adipocytes affect metabolism by mediating crosstalk at cellular or tissue level. You can read more about the research of the Scheele group at Translational Cell Metabolism in the Schéele Group. The Schéele group is a multidisciplinary and collaborative group with a strong international network within brown fat biology and metabolism. The group currently consists of 6 Postdocs, 1 Lab Technician, 1 PhD student, 1 Research Assistant and 1 Master student.
Project Description
The project aims to investigate the crosstalk between brown adipose tissue (BAT) with the pancreas and the liver in the regulation of glucose homeostasis, more specifically the effect of novel peptides secreted by BAT on the modulation of glucagon and insulin secretion, and gluconeogenesis pathways are investigated. The candidate must be familiar with cell culture and differentiation of IPSC into hepatocytes, and with handling pancreatic islets. The candidate will study crosstalk using high content screening approaches in human in vitro models. Interesting targets will subsequently be studied in vivo in various mouse models.
Profile
We are looking for a highly skilled, self-driven, positive, and collaborative scientist with the following competencies and qualifications:
Terms of employment
The postdoc position is a full-time position for 2 years. Starting date is January 15, 2024, or after agreement.
Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Depending on qualifications, a supplement may be negotiated.
Non-Danish and Danish applicants may be eligible for tax reductions if they hold a PhD degree and have not lived in Denmark the last 10 years.
The positions are covered by the “Memorandum on Job Structure for Academic Staff at the Universities” of June 28, 2013.
Questions
For further information about the position, please contact Associate Professor Camilla Schéele at [email protected]. For questions regarding the recruitment procedure, please contact SUND HR CBMR at [email protected]
International applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).
Application procedure
Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:
Application deadline: 5 November 2023, 23.59pm CET
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed, each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.
You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/
The applicants will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.
The University of Copenhagen wishes to reflect the diversity of society and welcome applications from all qualified candidates regardless of personal background.
Kilde: Jobnet.dk
Background
Our researchers share a common purpose as they seek to transform the basic understanding of the mechanisms involved in cardiometabolic health and disease, and to accelerate this knowledge towards new prevention and treatment strategies.
The Center has around 260 employees, spread across 22 research groups and 5 technology platforms, who work in a vibrant international research environment with a strong focus on interdisciplinary collaboration.
The Center’s research has resulted in seminal discoveries as to how genes, hormones, and environmental factors influence metabolic health and disease throughout life. You can read more about CBMR at www.cbmr.ku.dk.
Our group and research
The position available is in the Translational Cell Metabolism Group headed by Associate Professor Camilla Schéele. The research group studies human adipose tissue crosstalk. Major focus areas include human adipose tissue heterogeneity, brown fat recruitment and how secreted factors from brown adipocytes affect metabolism by mediating crosstalk at cellular or tissue level. You can read more about the research of the Scheele group at Translational Cell Metabolism in the Schéele Group. The Schéele group is a multidisciplinary and collaborative group with a strong international network within brown fat biology and metabolism. The group currently consists of 6 Postdocs, 1 Lab Technician, 1 PhD student, 1 Research Assistant and 1 Master student.
Project Description
The project aims to investigate the crosstalk between brown adipose tissue (BAT) with the pancreas and the liver in the regulation of glucose homeostasis, more specifically the effect of novel peptides secreted by BAT on the modulation of glucagon and insulin secretion, and gluconeogenesis pathways are investigated. The candidate must be familiar with cell culture and differentiation of IPSC into hepatocytes, and with handling pancreatic islets. The candidate will study crosstalk using high content screening approaches in human in vitro models. Interesting targets will subsequently be studied in vivo in various mouse models.
Profile
We are looking for a highly skilled, self-driven, positive, and collaborative scientist with the following competencies and qualifications:
- A PhD degree in Biology, Biochemistry, Molecular Pathology, Molecular Biology, Molecular Biomedicine, or related sciences
- Expertise in culturing and differentiating induced pluripotent stem cells into hepatocytes as well as culturing primary human hepatocytes
- Expertise in gluconeogenesis and glycogen metabolism assays
- Experience with functional studies of human and murine islets, including measurement of insulin and glucagon secretion
- Experience with immunoassays such as ELISA, and high sensitivity assays such as MSD.
- Expertise in imaging techniques such as Fluorescence in situ hybridization (FISH) using the RNAscope platform on islets, and hepatocytes
- Experience with histology techniques such as microtome sectioning, embedding, HE, and PAS staining
- Expertise in molecular biology techniques including RNA and DNA isolation, PCR, and RT-qPCR
- Experience in planning and performing in vivo studies such as compound administration, blood sampling, and histological analysis with a FELASA-accredited certificate corresponding to Laboratory Animal Science Function A/B/D
- Experience in working in an international environment
- Interest in human metabolism and drug screening
- Excellent English communication skills, both written and oral
Terms of employment
The postdoc position is a full-time position for 2 years. Starting date is January 15, 2024, or after agreement.
Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Depending on qualifications, a supplement may be negotiated.
Non-Danish and Danish applicants may be eligible for tax reductions if they hold a PhD degree and have not lived in Denmark the last 10 years.
The positions are covered by the “Memorandum on Job Structure for Academic Staff at the Universities” of June 28, 2013.
Questions
For further information about the position, please contact Associate Professor Camilla Schéele at [email protected]. For questions regarding the recruitment procedure, please contact SUND HR CBMR at [email protected]
International applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).
Application procedure
Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:
- Motivated letter of application (max. one page)
- Curriculum vitae (maximum of 2 pages; your ORCID must be included)
- Copies of MSc and PhD diplomas, including an authorized English translation if issued in other language than English or Danish. If the PhD is not completed, a signed statement from the institution or supervisor stating the date of completion is accepted.
- Full list of publications (journal impact factors at publication date must be included)
- References (name and contact details of at least two references)
Application deadline: 5 November 2023, 23.59pm CET
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed, each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.
You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/
The applicants will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.
The University of Copenhagen wishes to reflect the diversity of society and welcome applications from all qualified candidates regardless of personal background.
Kilde: Jobnet.dk
Information og data
Denne ledige stilling har jobtypen "Forsker", og befinder sig i kategorien "Sundhed og forskning".
Arbejdsstedet er beliggende i København N.
Jobbet er oprettet på vores service den 23.10.2023, men kan have været deaktiveret og genaktiveret igen.
Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
- Forsker
- København N
- Søndag den 05. november 2023
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