Principal Scientist Formulation Development
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We are seeking a dedicated Principal Scientist with expertise in formulation development for cell-based therapy.
About the department
The department Stem Cell Analytics and Formulation has been recently established and is part of Novo Nordisk’s Stem Cell R&D unit, where we develop novel cell replacement therapies for the treatment of serious chronic diseases. Our department focuses on the development of Analytical methods and characterization of Stem Cell Drug Products.
We assure the control of manufacturing processes across the entire pluripotent stem cell workflow. Diabetes mellitus type 1, Parkinson’s disease and chronic heart failure are only some of the indications currently in the pipeline.
You will join an international and dedicated Stem Cell CMC division of ~50 employees, including scientists, project leaders, laboratory technicians and student workers. We have expertise in analytical development, bioprocess development, stem cell biology and GMP compliance and truly believe that stem cell therapies will make a difference in the lives of patients. If this awakens your interest, please apply and support us in translating stem cell products into the clinics.
The position
We are seeking an experienced and dedicated Principal Scientist to expand the formulation development activities for stem cell products. The position is anchored in the Stem Cell Analytics and Formulation department in the greater Copenhagen area.
These activities will require tight collaboration with other departments within Stem Cell R&D, such as Process Development and Delivery & Pharmacology. In the field of cell therapy, drug products are typically the result of long and complex in vitro differentiation protocols which have a profound impact on the functional properties of cellular products. Timely screening of parameters and development of suitable formulations which allow accurate dosing and which can positively impact quality and yield are a key success factor.
In this position you will drive the characterization of different formulations and evaluation of stability and suitability of differentiated derivatives of stem cell banks in final formulations. You will collaborate cross-departmentally with material engineers and device development experts to optimize formulations for both individual as well as drug-device combination products. Through your in-depth understanding of analytical technology, evaluation of biomaterials and experience in data-driven approaches you will assure successful development of cell therapy products for different routes of administration. Your function is rounded off by your contribution to regulatory documents and meeting packages and interaction with health authorities in different geographical regions.
Qualifications
You must hold a PhD degree in Biology, Biotechnology or a similar field of studies. You have more than 7 years of work experience in the biotech or pharmaceutical industry with several of these years in the development of drug product formulations for Biologics or cell therapy products. You are familiar with rheology of low viscosity liquids as well as cell-biomaterial interactions and ideally have gathered first experience with combination products in a preclinical or clinical context. You should have a strong scientific background in cellular and molecular biology and have experience in developing and working with a wide range of analytical methods. Experience with DoEs and automation equipment would be an advantage.
This position requires you to be a dedicated and result-oriented team player who enjoys working in an innovative, international and open-minded environment. You excel in stakeholder management and can easily collaborate cross-departmentally, have a sound personal judgement and are used to clearly present scientific data.
This role can be on the level of Senior Scientist or Principal Scientist. A ranking will be performed based on the individual experience level and qualification of a suitable candidate.
Working at Novo Nordisk
At Novo Nordisk, your skills, dedication and ambition help us change lives for the better for patients around the world. In exchange, we offer you an opportunity to work with extraordinary talent and to benefit from a range of possibilities for professional and personal development.
Contact
For further information, please contact Malte Wittmann at [email protected].
Deadline
Please note that applications will be reviewed continuously, and interviews will be planned as soon as a suitable candidate is identified.
Millions rely on us
To work for Novo Nordisk you will need the skills, dedication and ambition to change lives for the better for millions of patients living with diabetes and other chronic diseases. In exchange, we offer the chance to be part of a truly global workplace, where passion and engagement are met with opportunities for professional and personal development.
Information og data
Denne ledige stilling har jobtypen "Forsker", og befinder sig i kategorien "Sundhed og forskning".
Arbejdsstedet er beliggende i Måløv.
Jobbet er oprettet på vores service den 12.11.2020, men kan have været deaktiveret og genaktiveret igen.
Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
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