Scientist for recombinant incorporation of non-canonical amino acids

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Research & Development
Denmark - Måløv

We are looking for an experienced scientist to work on microbial recombinant incorporation of non-canonical amino acids (ncAA) in pharmaceutical peptides and proteins. If you find tasks like these exciting and challenging, you may be our new colleague.

About the department
Microbial Expression (MiE) is part of Recombinant Technologies and has microbial strain engineering, protein engineering and protein production as core tasks. The primary responsibility of MiE is to ensure timely support to our research projects with a broad range of protein expression technologies, strain optimization tools and production strains.

The job
As a scientist in MiE your primary focus will be on strain and protein engineering for ncAA incorporation, molecular genetic strategies for improving production and/or quality of proteins with ncAAs and screening and characterization of strains incorporating such. We offer a challenging research environment where we work closely together with dedicated scientists across the organization, including specialists within the disease-areas, mammalian expression systems, immuno-technology, cell culture, robotics and protein technology. The position offers excellent opportunities for developing scientific and personal competences within an international organization. We value a collaborative, positive, honest and responsible attitude and strive for high scientific standards to secure progress for our teams and projects.

Qualifications

The preferred candidate is an excellent molecular biologist holding a relevant scientific degree (biology, biochemistry, biotechnology, engineering or similar) supplemented with a PhD and preferably 5 years industrial experience within e.g. synthetic biology, microbial molecular genetics and/or high-throughput automation of molecular biology methods aiming at ncAA incorporation.

You have extensive insight into intracellular molecular dynamics and compartmentalization in yeast and how complex interactions can affect expression of heterologous proteins. Prior experience with development of yeast and/or bacterial hosts incorporating ncAAs, targeted multiplex genome editing tools and application of automated procedures for protein engineering, screening and characterization, as well as hands-on experience with next-generation sequencing tools and handling of large datasets with e.g. Python or other high-level, general-purpose programming languages will be beneficial.

You cover all aspects of the experimental work from planning and design of experiments over practical execution of experiments to documentation and presentation of the results to colleagues across the organization. You understand the intellectual property, quality and practical requirements involved in the development of recombinant proteins and peptides for human therapeutic use.
Efficient communication, collaboration and knowledge sharing are some of your important qualities as well as being flexible and capable of adapting in an often-changing research environment.

Solid English capabilities are required for writing documentation and for communication with colleagues in a multinational corporation.
At Novo Nordisk, we strive for excellence. As a world leader in diabetes care and a major player in haemostasis management, obesity treatment, growth hormone therapy and hormone replacement therapy, we offer our employees opportunities for continuous growth.

Contact
For further information, please call Michael Skjøt on +45 3079 7230 or Kjeld Olesen on +45 3075 2821

Deadline
December 17. 2020

We expect to invite for first interviews in the beginning of January 2021

Millions rely on us
To work for Novo Nordisk you will need the skills, dedication and ambition to change lives for the better for millions of patients living with diabetes and other chronic diseases. In exchange, we offer the chance to be part of a truly global workplace, where passion and engagement are met with opportunities for professional and personal development.


Information og data

Denne ledige stilling har jobtypen "Forsker", og befinder sig i kategorien "Sundhed og forskning".

Arbejdsstedet er beliggende i Måløv.

Jobbet er oprettet på vores service den 18.11.2020, men kan have været deaktiveret og genaktiveret igen.

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Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
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