Postdoctoral Fellowship in Single Cell Proteomics Technology and Chromatin Biology
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Odense M
The Protein Research Group (Professor Ole Nørregaard Jensen) at the Department of Biochemistry and Molecular Biology at the University of Southern Denmark (SDU), Odense invites applications for a three-year postdoctoral research position in single cell proteomics and chromatin biology.
The research project entails the development and application of single cell proteomics and mass spectrometry technologies for studies of epigenetic and transcriptional regulation of chromatin. The main focus will be on the development of high-sensitivity bioanalytical technologies for isolation and detailed characterization of chromatin binding proteins, including histones and their post-translational modifications.
You will be part of an international and dynamic research team. You will be motivated to use capillary liquid chromatography, mass spectrometry and computational tools and develop new approaches to investigate regulatory events in chromatin biology at the single cell level. You will be responsible for implementing mass spectrometry based technologies for high-sensitivity quantitative studies of proteins and their dynamic post-translational modifications. You will manage independent research projects and assist in the supervision of undergraduate and graduate students.
The position is to be filled by 1 October 2020 or soon thereafter. Application deadline: 10 August 2020.
Qualifications
We are looking for a highly motivated and enthusiastic scientist with excellent communication skills.
For consideration, applicants must have:
• A recent PhD degree in biochemistry, protein science/proteomics, analytical biochemistry or a similar field
• Demonstrated experience in experimental protein biochemistry and mass spectrometry
• Interest in the study of bioanalytical technologies and their applications in chromatin biology
• Publications in high-quality international peer-reviewed journals
• Excellent English speaking, reading and writing skills.
In addition, applicants with one or more of the following types of experience will be preferred:
• Working experience with nanoliter flow LC-MS/MS using Orbitrap or Q-TOF instruments
• Experience with biochemical characterization of chromatin and the chromatin proteome
• Advanced knowledge of physical chemistry and bioanalytical instruments
• Computational proteomics and data analysis, including R scripting.
The Jensen laboratory is part of the Protein Research Group and offers a strong international research environment in protein chemistry, biomolecular mass spectrometry, and computational proteomics with focus on elucidating the functional roles of dynamic post-translational modifications of proteins. The VILLUM Center for Bioanalytical Sciences at SDU and the national PRO-MS research infrastructure provide world-class facilities for proteomics and mass spectrometry research, including Orbitrap mass spectrometers (Eclipse, Lumos, Exploris).
Recent publications on mass spectrometry, proteomics and chromatin biology by the ON Jensen group include Shliaha et al (2020) Anal. Chem. 92(3) 2364.2368; Radzisheuskaya et al (2019) Nat. Struct. Mol. Biol. (26)11 999-1012; Tvardovskiy et al (2017) Nucleic Acids Res. 45(16):9272-9289.
Place of work:
Protein Research Group (Professor Ole N. Jensen), Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.
For further information please contact Ole Nørregaard Jensen, [email protected].
Application, salary etc.
The successful applicant will be employed in accordance with the agreement between the Ministry of Finance and AC (the Danish Confederation of Professional Associations). Please check links for more information on salary and taxation.
The application must include the following:
• A curriculum vitae including information on previous employment.
• A full list of publications stating the scientific publications on which the applicant wishes to rely.
Shortlisting may be used in the assessment process.
Incomplete applications and applications received after the deadline will neither be considered nor evaluated.
To qualify you must have passed a PhD or equivalent. Applications will be assessed by an expert assessor/committee. Applicants will be informed of their assessment by the university.
The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.
Applications must be submitted electronically using the link "Apply online". Attached files must be in Adobe PDF or Word format. Each box can only contain a single file of max. 10 Mb. We strongly recommend that you read How to apply before you apply.
Further information for international applicants about entering and working in Denmark.
The research project entails the development and application of single cell proteomics and mass spectrometry technologies for studies of epigenetic and transcriptional regulation of chromatin. The main focus will be on the development of high-sensitivity bioanalytical technologies for isolation and detailed characterization of chromatin binding proteins, including histones and their post-translational modifications.
You will be part of an international and dynamic research team. You will be motivated to use capillary liquid chromatography, mass spectrometry and computational tools and develop new approaches to investigate regulatory events in chromatin biology at the single cell level. You will be responsible for implementing mass spectrometry based technologies for high-sensitivity quantitative studies of proteins and their dynamic post-translational modifications. You will manage independent research projects and assist in the supervision of undergraduate and graduate students.
The position is to be filled by 1 October 2020 or soon thereafter. Application deadline: 10 August 2020.
Qualifications
We are looking for a highly motivated and enthusiastic scientist with excellent communication skills.
For consideration, applicants must have:
• A recent PhD degree in biochemistry, protein science/proteomics, analytical biochemistry or a similar field
• Demonstrated experience in experimental protein biochemistry and mass spectrometry
• Interest in the study of bioanalytical technologies and their applications in chromatin biology
• Publications in high-quality international peer-reviewed journals
• Excellent English speaking, reading and writing skills.
In addition, applicants with one or more of the following types of experience will be preferred:
• Working experience with nanoliter flow LC-MS/MS using Orbitrap or Q-TOF instruments
• Experience with biochemical characterization of chromatin and the chromatin proteome
• Advanced knowledge of physical chemistry and bioanalytical instruments
• Computational proteomics and data analysis, including R scripting.
The Jensen laboratory is part of the Protein Research Group and offers a strong international research environment in protein chemistry, biomolecular mass spectrometry, and computational proteomics with focus on elucidating the functional roles of dynamic post-translational modifications of proteins. The VILLUM Center for Bioanalytical Sciences at SDU and the national PRO-MS research infrastructure provide world-class facilities for proteomics and mass spectrometry research, including Orbitrap mass spectrometers (Eclipse, Lumos, Exploris).
Recent publications on mass spectrometry, proteomics and chromatin biology by the ON Jensen group include Shliaha et al (2020) Anal. Chem. 92(3) 2364.2368; Radzisheuskaya et al (2019) Nat. Struct. Mol. Biol. (26)11 999-1012; Tvardovskiy et al (2017) Nucleic Acids Res. 45(16):9272-9289.
Place of work:
Protein Research Group (Professor Ole N. Jensen), Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.
For further information please contact Ole Nørregaard Jensen, [email protected].
Application, salary etc.
The successful applicant will be employed in accordance with the agreement between the Ministry of Finance and AC (the Danish Confederation of Professional Associations). Please check links for more information on salary and taxation.
The application must include the following:
• A curriculum vitae including information on previous employment.
• A full list of publications stating the scientific publications on which the applicant wishes to rely.
Shortlisting may be used in the assessment process.
Incomplete applications and applications received after the deadline will neither be considered nor evaluated.
To qualify you must have passed a PhD or equivalent. Applications will be assessed by an expert assessor/committee. Applicants will be informed of their assessment by the university.
The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.
Applications must be submitted electronically using the link "Apply online". Attached files must be in Adobe PDF or Word format. Each box can only contain a single file of max. 10 Mb. We strongly recommend that you read How to apply before you apply.
Further information for international applicants about entering and working in Denmark.
Information og data
Denne ledige stilling har jobtypen "Forsker", og befinder sig i kategorien "Sundhed og forskning".
Arbejdsstedet er beliggende i Odense M.
Jobbet er oprettet på vores service den 2.7.2020, men kan have været deaktiveret og genaktiveret igen.
Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
- Forsker
- Odense M
- Mandag den 10. august 2020
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