Postdoc in Brown Adipose Tissue Biology, Chromatin and Metabolic Disease in ERC-funded Research Group

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Odense M

A position as postdoctoral fellow is available at the Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, with a flexible starting date (preferably 1 May 2021 or earlier). The position is funded for two years with the possibility for extension. Application deadline: 15 February 2021.

The employee will be part of Jan-Wilhelm Kornfeld’s ERC-funded international research group and shares our interest in understanding the role of dietary restriction and obesity in adipose tissue chromatin regulation, and in elucidating the effects of these chromatin changes for energy homeostasis and Metabolic Disease. For this, we utilize advanced genomics methods like RNA- and ChIP-Seq, computational approaches and transgenic mouse models.

We are seeking an enthusiastic and self-motivated colleague with a PhD degree in life sciences (biologist, biochemist, biomedical degree or related) who is interested in understanding chromatin dynamics and histone posttranslational modifications during diet-induced-obesity in mice. A background in NGS and/or experience in analysing mouse models of obesity and T2D is a plus.

The recruited scientist will be associated with ADIPOSIGN, a new research centre established in 2019 for a six-year period through a major grant from the Novo Nordisk Foundation. ADIPOSIGN combines experimental and computational systems approaches to obtain insights into how fat cells receive and respond to signals at the level of the (epi)-genome and the cell membrane. Our goal is to understand how the signalling states of adipocytes depend on depot, gender, and genetic variation, and how changes in these signalling states during obesity contribute to its patho-physiological consequences.

The future colleague will actively contribute to other research projects in the group and will constitute a central part of an ambitious, international team of young and ambitious scientists.

The ideal candidate is comfortable with one or many of the following:

  • Handling and metabolic phenotyping of transgenic mice.
  • Performing NGS experiments (library preparation and analysis of RNA-Seq and ChiP-Seq data).
  • Molecular and ex vivo techniques (primary adipocyte cell culture, cell lines, qPCR, Western Blot).
  • Assisting in grant funding applications, training of students and guests.
  • Contributing to teaching activities in English.

Your education and background:

  • A PhD degree in life sciences with a special focus on physiology and chromatin biology.
  • Ideally one first authorship in a high impact journal or a in field-specific journal.
  • Proficiency in R and willingness to receive training in in silico analysis of NGS data.
  • A team player with good collaborative and interpersonal skills.
  • An enthusiastic, positive attitude towards science and its contribution to society.
  • Diligence and intellectual flexibility as required for an academic position.
  • An open and positive mind that contributes to the success of the whole research team.

For further information please contact Professor Jan-Wilhelm Kornfeld by e-mail [email protected] or phone +45 9350 7481.

Application, salary etc.
The successful applicant will be employed in accordance with the agreement between the Ministry of Finance and AC (the Danish Confederation of Professional Associations). Please check links for more information on salary and taxation.

The application must include the following:
• A curriculum vitae including information on previous employment.
• A full list of publications stating the scientific publications on which the applicant wishes to rely.

Shortlisting may be used in the assessment process.

Incomplete applications and applications received after the deadline will neither be considered nor evaluated.

To qualify you must have passed a PhD or equivalent. Applications will be assessed by an expert assessor/committee. Applicants will be informed of their assessment by the university.

The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.

Applications must be submitted electronically using the link "Apply online". Attached files must be in Adobe PDF or Word format. Each box can only contain a single file of max. 10 Mb. We strongly recommend that you read How to apply before you apply.

Further information for international applicants about entering and working in Denmark.


Information og data

Denne ledige stilling har jobtypen "Forsker", og befinder sig i kategorien "Sundhed og forskning".

Arbejdsstedet er beliggende i Odense M.

Jobbet er oprettet på vores service den 21.1.2021, men kan have været deaktiveret og genaktiveret igen.

Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
  • Forsker
  • Odense M
  • Mandag den 15. februar 2021

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