PhD Scholarship to Study Plasticity of Adipose Tissue at Single Cell Resolution REANNOUNCEMENT
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Odense M
Due to technical problems and maintenance of the servers at SDU, the application deadline is extended till 5 September 2021.
The Center for Functional Genomics and Tissue Plasticity (ATLAS) at the Functional Genomics & Metabolism Research Unit, Department of Biochemistry and Molecular Biology, University of Southern Denmark, invites applications from outstanding candidates who are interested in joining our team and the Mandrup Group as a PhD fellow. The position is available from 1 October 2021 or as soon as possible thereafter. Application deadline: 5 September 2021.
ATLAS
The overall aim of Center for Functional Genomics and Tissue Plasticity (ATLAS) is to obtain systems-level, mechanistic and cell type-resolved understanding of adipose and hepatic tissue plasticity in response to diet-induced obesity and regression. We apply a combination of functional genomics approaches, including single cell-sequencing, proteomics, in vivo targeting, and computational biology to obtain in depth mechanistic understanding of the plasticity of these tissues in mouse models as well as in humans undergoing weight-reducing surgery. ATLAS is supported by the Danish National Research Foundation.
The centre involves the following PIs:
Susanne Mandrup, Professor, Department of Biochemistry and Molecular Biology (Director)
Søren Kragh Moestrup, Professor, Department of Molecular Medicine
Blagoy Blagoev, Professor, Department of Biochemistry and Molecular Biology
Aleksander Krag, Professor, Institute of Clinical Medicine & Odense University Hospital
Lars Grøntved, Associate Professor, Department of Biochemistry and Molecular Biology
Jonas Graversen, Associate Professor, Department of Molecular Medicine
Kim Ravnskjær, Associate Professor, Department of Biochemistry and Molecular Biology
Jesper Grud Skat Madsen, Assistant Professor, Department of Biochemistry and Molecular Biology
About the research project and what we offer
As a PhD fellow in the Mandrup Group you will be involved in a highly ambitious and interdisciplinary research environment investigating gene regulatory networks controlling adipocyte differentiation, function, and adipose tissue plasticity. The group has recently established single cell sequencing technologies for both mouse and human adipose tissue, and your project will build on these data. In collaboration with other PhD students and postdocs, you will uncover transcriptional networks in specific cell populations as well as crosstalk between cell types and newly defined subpopulations in adipose tissue of mouse models and human subjects. Furthermore, you will work with clinicians to link molecular features of adipose tissue to clinical phenotypes.
We offer:
The research environment
ATLAS and the Mandrup Group is based in the Functional Genomics & Metabolism Research Unit, which constitutes an international, ambitious, highly dynamic, and well-equipped working environment. The unit and the department have state-of-the-art facilities for next generation sequencing, single-cell transcriptomics, flow cytometry, mass spectrometry, metabolomics, bioimaging and transgenic mouse work. Strategic research alliances exist with Odense University Hospital (OUH).
Qualifications/requirements
We are looking for highly motivated, dedicated, and ambitious candidates with:
Documented hands-on experience with NGS data analysis, adipocyte biology, and mouse models is considered an advantage .
For further information please contact Centre Director Professor Susanne Mandrup ([email protected]).
Application, salary etc.
The appointment as a PhD Research Fellow is for three years. Employment stops automatically at the end of the period. The holder of the scholarship is not allowed to have other paid employment during the three-year period.
The successful applicant will be employed in accordance with the agreement on salaried PhD scholars between the Ministry of Finance and AC (the Danish Confederation of Professional Associations). Please check links for more information on salary and taxation.
The successful candidate will be enrolled at this university in accordance with faculty regulations and the Danish Ministerial Order on the PhD Programme at the Universities (PhD order).
The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.
The application must be in English and include the following:
Incomplete applications and applications received after the deadline will neither be considered nor evaluated.
Shortlisting may be used in the assessment process.
Applicants will be informed of their assessment by the university.
Further information about the PhD-study can be found at the homepage of the University.
Please access the application form directly via the SDU job portal. You can find information on all open positions in ATLAS via the ATLAS homepage.
Applications must be submitted electronically using the link "Apply online". Attached files must be in Adobe PDF or Word format. Each box can only contain a single file of max. 10 Mb. We strongly recommend that you read How to apply before you apply.
Incomplete applications and applications received after the deadline will neither be considered nor evaluated. This also applies to reference letters.
Further information for international applicants about entering and working in Denmark.
The Center for Functional Genomics and Tissue Plasticity (ATLAS) at the Functional Genomics & Metabolism Research Unit, Department of Biochemistry and Molecular Biology, University of Southern Denmark, invites applications from outstanding candidates who are interested in joining our team and the Mandrup Group as a PhD fellow. The position is available from 1 October 2021 or as soon as possible thereafter. Application deadline: 5 September 2021.
ATLAS
The overall aim of Center for Functional Genomics and Tissue Plasticity (ATLAS) is to obtain systems-level, mechanistic and cell type-resolved understanding of adipose and hepatic tissue plasticity in response to diet-induced obesity and regression. We apply a combination of functional genomics approaches, including single cell-sequencing, proteomics, in vivo targeting, and computational biology to obtain in depth mechanistic understanding of the plasticity of these tissues in mouse models as well as in humans undergoing weight-reducing surgery. ATLAS is supported by the Danish National Research Foundation.
The centre involves the following PIs:
Susanne Mandrup, Professor, Department of Biochemistry and Molecular Biology (Director)
Søren Kragh Moestrup, Professor, Department of Molecular Medicine
Blagoy Blagoev, Professor, Department of Biochemistry and Molecular Biology
Aleksander Krag, Professor, Institute of Clinical Medicine & Odense University Hospital
Lars Grøntved, Associate Professor, Department of Biochemistry and Molecular Biology
Jonas Graversen, Associate Professor, Department of Molecular Medicine
Kim Ravnskjær, Associate Professor, Department of Biochemistry and Molecular Biology
Jesper Grud Skat Madsen, Assistant Professor, Department of Biochemistry and Molecular Biology
About the research project and what we offer
As a PhD fellow in the Mandrup Group you will be involved in a highly ambitious and interdisciplinary research environment investigating gene regulatory networks controlling adipocyte differentiation, function, and adipose tissue plasticity. The group has recently established single cell sequencing technologies for both mouse and human adipose tissue, and your project will build on these data. In collaboration with other PhD students and postdocs, you will uncover transcriptional networks in specific cell populations as well as crosstalk between cell types and newly defined subpopulations in adipose tissue of mouse models and human subjects. Furthermore, you will work with clinicians to link molecular features of adipose tissue to clinical phenotypes.
We offer:
- A three-year PhD position in a highly stimulating, supportive, international, and interdisciplinary research environment
- Access to state-of-the-art equipment, facilities and infrastructure
- Opportunity to interact with an extensive network of national and international collaborators
- A competitive salary and social benefits (e.g. health coverage, parental leave, social security etc.)
- Dedicated assistance and support with various practical, social, and legal aspects (housing, visa, administration, tax etc.), especially for international candidates through our international staff office (ISO) and department
The research environment
ATLAS and the Mandrup Group is based in the Functional Genomics & Metabolism Research Unit, which constitutes an international, ambitious, highly dynamic, and well-equipped working environment. The unit and the department have state-of-the-art facilities for next generation sequencing, single-cell transcriptomics, flow cytometry, mass spectrometry, metabolomics, bioimaging and transgenic mouse work. Strategic research alliances exist with Odense University Hospital (OUH).
Qualifications/requirements
We are looking for highly motivated, dedicated, and ambitious candidates with:
- A Master’s degree in Life Science, preferably Molecular Biology, Biomedicine, or Computational Systems Biology
- Strong communication and collaborative skills and an interest in working in an interdisciplinary environment
- Proficiency in spoken and written English.
Documented hands-on experience with NGS data analysis, adipocyte biology, and mouse models is considered an advantage .
For further information please contact Centre Director Professor Susanne Mandrup ([email protected]).
Application, salary etc.
The appointment as a PhD Research Fellow is for three years. Employment stops automatically at the end of the period. The holder of the scholarship is not allowed to have other paid employment during the three-year period.
The successful applicant will be employed in accordance with the agreement on salaried PhD scholars between the Ministry of Finance and AC (the Danish Confederation of Professional Associations). Please check links for more information on salary and taxation.
The successful candidate will be enrolled at this university in accordance with faculty regulations and the Danish Ministerial Order on the PhD Programme at the Universities (PhD order).
The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.
The application must be in English and include the following:
- A letter stating your specific interest, motivation and qualifications for the project in question (max. one pages) (please attach this under box "Application form")
- A description of your research interests in relation to the overall aim of the project (max one page excluding references)
- Detailed CV, including personal contact information, education, work/research experience and skills relevant for the position, publications/manuscripts
- Copies of diplomas, bachelor as well as master’s degree, including transcript of notes/grades. If awaiting master’s diploma, provide a written statement from the supervisor.
- At least two signed reference letters (with referee contact details and relationship). Should your referees wish to send their letters directly to us, please have them use e-mail: [email protected] mentioning your name and the title of the position in the subject line. And please note that these also need to reach us before deadline.
Incomplete applications and applications received after the deadline will neither be considered nor evaluated.
Shortlisting may be used in the assessment process.
Applicants will be informed of their assessment by the university.
Further information about the PhD-study can be found at the homepage of the University.
Please access the application form directly via the SDU job portal. You can find information on all open positions in ATLAS via the ATLAS homepage.
Applications must be submitted electronically using the link "Apply online". Attached files must be in Adobe PDF or Word format. Each box can only contain a single file of max. 10 Mb. We strongly recommend that you read How to apply before you apply.
Incomplete applications and applications received after the deadline will neither be considered nor evaluated. This also applies to reference letters.
Further information for international applicants about entering and working in Denmark.
Information og data
Denne ledige stilling har jobtypen "Forsker", og befinder sig i kategorien "Sundhed og forskning".
Arbejdsstedet er beliggende i Odense M.
Jobbet er oprettet på vores service den 26.7.2021, men kan have været deaktiveret og genaktiveret igen.
Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
- Forsker
- Odense M
- Søndag den 05. september 2021
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