Postdoc Position for Studying Epigenetic Regulation of Breast Cancer Progression
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Odense M
A 2½-year postdoc position for studying the epigenetic mechanisms that control breast cancer progression is available in the group of Rasmus Siersbæk at the Functional Genomics & Metabolism Research Unit at Department of Biochemistry and Molecular Biology, University of Southern Denmark. The position is available from 1 December 2022 or soon thereafter. Application deadline is 1 November 2022.
Research Project
Breast cancer is the most common type of cancer affecting women. Transcriptional and epigenetic mechanisms are important for driving later stages of the disease, where disseminated cancer cells form secondary tumours in distant organs in the process of metastasis. You will lead a project that aims to understand the epigenetic mechanisms that control breast cancer growth, treatment response and metastasis to identify potential new avenues for treating this disease. You will apply a range of omics technologies, including single-cell transcriptomics in combination with pooled CRISPR screens, to functionally investigate the role of key epigenetic regulators in controlling different stages of breast cancer progression and treatment responses. The goal is to identify potential new epigenetic treatment opportunities and validate these in pre-clinical models.
Lab and Research Environment
You will be part of a dynamic, supportive, and ambitious research group consisting of both postdocs, PhD students, and undergraduate students. Our group applies advanced functional genomics and proteomics approaches, including single-cell methodologies, to understand how transcriptional mechanisms shape cell function in the context of cancer. We are positioned in the Functional Genomics and Metabolism Research Unit at Department of Biochemistry and Molecular Biology, University of Southern Denmark. Our unit currently hosts seven independent research groups with a strong focus on chromatin and transcriptional mechanisms in health and disease. It is an innovative, collaborative, and international research environment with a strong scientific and social network for students and postdocs. As part of the unit, you will have access to world-class facilities for next generation sequencing, single-cell technologies, flow cytometry, animal work, mass spectrometry, and bioimaging.
Your Profile
We are looking for a highly motivated, innovative, and collaborative postdoc to lead this project together with undergraduate students. You have:
Expertise in functional genomics technologies and relevant computational skills are considered advantageous.
We Offer
For further information, please visit our homepage or contact Associate Professor Rasmus Siersbæk at [email protected] or +45 6550 2492.
Application, salary etc.
The successful applicant will be employed in accordance with the agreement between the Ministry of Finance and AC (the Danish Confederation of Professional Associations). Please check links for more information on salary and taxation.
The application must include the following:
• A curriculum vitae including information on previous employment.
• A full list of publications stating the scientific publications on which the applicant wishes to rely.
Shortlisting may be used in the assessment process.
Incomplete applications and applications received after the deadline will neither be considered nor evaluated.
To qualify you must have passed a PhD or equivalent. Applications will be assessed by an expert assessor/committee. Applicants will be informed of their assessment by the university.
The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.
Applications must be submitted electronically using the link "Apply online". Attached files must be in Adobe PDF or Word format. Each box can only contain a single file of max. 10 Mb. We strongly recommend that you read How to apply before you apply.
Further information for international applicants about entering and working in Denmark.
Research Project
Breast cancer is the most common type of cancer affecting women. Transcriptional and epigenetic mechanisms are important for driving later stages of the disease, where disseminated cancer cells form secondary tumours in distant organs in the process of metastasis. You will lead a project that aims to understand the epigenetic mechanisms that control breast cancer growth, treatment response and metastasis to identify potential new avenues for treating this disease. You will apply a range of omics technologies, including single-cell transcriptomics in combination with pooled CRISPR screens, to functionally investigate the role of key epigenetic regulators in controlling different stages of breast cancer progression and treatment responses. The goal is to identify potential new epigenetic treatment opportunities and validate these in pre-clinical models.
Lab and Research Environment
You will be part of a dynamic, supportive, and ambitious research group consisting of both postdocs, PhD students, and undergraduate students. Our group applies advanced functional genomics and proteomics approaches, including single-cell methodologies, to understand how transcriptional mechanisms shape cell function in the context of cancer. We are positioned in the Functional Genomics and Metabolism Research Unit at Department of Biochemistry and Molecular Biology, University of Southern Denmark. Our unit currently hosts seven independent research groups with a strong focus on chromatin and transcriptional mechanisms in health and disease. It is an innovative, collaborative, and international research environment with a strong scientific and social network for students and postdocs. As part of the unit, you will have access to world-class facilities for next generation sequencing, single-cell technologies, flow cytometry, animal work, mass spectrometry, and bioimaging.
Your Profile
We are looking for a highly motivated, innovative, and collaborative postdoc to lead this project together with undergraduate students. You have:
- A PhD in Life Science, e.g. Molecular Biology or Biomedicine.
- Experience with cancer research.
- Strong communication and collaborative skills.
- Proficiency in spoken and written English.
Expertise in functional genomics technologies and relevant computational skills are considered advantageous.
We Offer
- A 2½-year postdoc position in a stimulating, international, and supportive research environment.
- Training in omics technologies, including single-cell analysis, as well as research management, oral and written communication, and networking.
- Access to state-of-the-art equipment and facilities.
- A supportive scientific and social network for students and postdocs, including mentoring and career development.
- A competitive salary and social benefits (e.g. health coverage, parental leave, social security etc.).
- Support with practical, social, and legal aspects (e.g. housing, visa, tax etc.) through our international staff office (ISO) and the department.
For further information, please visit our homepage or contact Associate Professor Rasmus Siersbæk at [email protected] or +45 6550 2492.
Application, salary etc.
The successful applicant will be employed in accordance with the agreement between the Ministry of Finance and AC (the Danish Confederation of Professional Associations). Please check links for more information on salary and taxation.
The application must include the following:
• A curriculum vitae including information on previous employment.
• A full list of publications stating the scientific publications on which the applicant wishes to rely.
Shortlisting may be used in the assessment process.
Incomplete applications and applications received after the deadline will neither be considered nor evaluated.
To qualify you must have passed a PhD or equivalent. Applications will be assessed by an expert assessor/committee. Applicants will be informed of their assessment by the university.
The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.
Applications must be submitted electronically using the link "Apply online". Attached files must be in Adobe PDF or Word format. Each box can only contain a single file of max. 10 Mb. We strongly recommend that you read How to apply before you apply.
Further information for international applicants about entering and working in Denmark.
Information og data
Denne ledige stilling har jobtypen "Forsker", og befinder sig i kategorien "Sundhed og forskning".
Arbejdsstedet er beliggende i Odense M.
Jobbet er oprettet på vores service den 11.10.2022, men kan have været deaktiveret og genaktiveret igen.
Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
- Forsker
- Odense M
- Tirsdag den 01. november 2022
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