PhD Position in Bacterial Cell Biology in Polymicrobial Community
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Odense M
At the Department of Biochemistry and Molecular Biology we are looking for a PhD student to join the lab of Assistant Professor Lin Lin, starting from 1 March 2023 (negotiable) at the earliest, for a period of three years. Application deadline: 31 January 2023.
The new lab will be conducting research on the understanding of the molecular cell biology of bacterial interspecies interaction, as well as host-pathogen interaction, using model organisms such as ESKAPE pathogen Acinetobacter baumannii. The PhD project is aiming to explore what and how different cellular processes are coordinated during Acinetobacter interaction with other bacteria in polymicrobial community at the molecular and single-cell level, using a combination of molecular microbiology, -omics and especially high-resolution live-cell imaging. Moreover, the project will also involve studying the spatial and temporal dynamics of interbacterial interaction.
We offer:
We are looking for a candidate who has:
For more information about this position and project, please contact Dr Lin Lin, [email protected].
Reference papers:
Lin, L., Capozzoli, R., Ferrand, A., Plum. M., Vettiger. A., & Basler, M. (2022) Subcellular localization of Type VI secretion system assembly in response to cell-cell contact. EMBO J, 41(13):e108595.
Lin, L., Ringel, P., Vettiger, A., Dürr, L., & Basler, M. (2019) DNA uptake upon T6SS-dependent prey cell lysis induces SOS response and reduces fitness of Acinetobacter baylyi. Cell Reports 29(6):1633-1644.e4.
Lin L., Lezan, E., Schmidt, A., & Basler, M. (2019) Abundance of bacterial Type VI secretion system components measured by targeted proteomics. Nature Communications 10, 2584.
Application, salary etc.
Appointment as a PhD Research Fellow is for three years. Employment stops automatically at the end of the period. The holder of the scholarship is not allowed to have other paid employment during the three-year period.
The successful applicant will be employed in accordance with the agreement on salaried PhD scholars between the Ministry of Finance and AC (the Danish Confederation of Professional Associations). Please check links for more information on salary and taxation.
The successful candidate will be enrolled at this university in accordance with faculty regulations and the Danish Ministerial Order on the PhD Programme at the Universities (PhD order).
The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.
Application must be in English and made in the form of a Declaration of Interest including the following:
• A research proposal/description of your approach to the above project (max one page excluding references)
• A letter stating your specific interest, motivation and qualifications for the project in question (max. two pages) (please attach this under box "Application form")
• Detailed CV, including personal contact information
• Copies of diplomas, Bachelor as well as Master’s degree, including transcript of notes/grades
• At least two signed reference letters. Should your referees wish to send their letters directly to us, please have them use e-mail: [email protected] mentioning your name and the title of the position in the subject line. And please note that these also need to reach us before deadline.
Shortlisting may be used in the assessment process.
Further information about the PhD-study can be found at the homepage of the University.
Applications must be submitted electronically using the link "Apply online". Attached files must be in Adobe PDF or Word format. Each box can only contain a single file of max. 10 Mb. We strongly recommend that you read How to apply before you apply.
Incomplete applications and applications received after the deadline will neither be considered nor evaluated. This also applies to reference letters.
Further information for international applicants about entering and working in Denmark.
The new lab will be conducting research on the understanding of the molecular cell biology of bacterial interspecies interaction, as well as host-pathogen interaction, using model organisms such as ESKAPE pathogen Acinetobacter baumannii. The PhD project is aiming to explore what and how different cellular processes are coordinated during Acinetobacter interaction with other bacteria in polymicrobial community at the molecular and single-cell level, using a combination of molecular microbiology, -omics and especially high-resolution live-cell imaging. Moreover, the project will also involve studying the spatial and temporal dynamics of interbacterial interaction.
We offer:
- Fully funded position for three years
- Fully equipped shared laboratories and highly supportive environment at the research unit Molecular Microbiology, as well as state-of-the- art facilities for support
- International collaborative work environment
- Unique opportunity to be first-hand involved in building a brand new lab group at early stage of your career
- Opportunity to be involved in teaching and supervising undergraduate or master students.
We are looking for a candidate who has:
- A Master's degree in Biochemistry, Molecular Biology, Cell Biology or Microbiology, or expectancy to complete the Master's degree by 31 January 2023. Interdisciplinary students with a background in microbiology are also welcome to apply.
- Ideally a good experimental background in molecular microbiology. Hand-on experience with fluorescence microscopy will be a plus.
- A high intrinsic motivation and capacity for independent work. You must be open-minded to different research ideas and challenges, and bold ideas are very welcome.
- Good communication and collaborative skills and proficiency in spoken and written English. You will work and discuss closely with PI and other colleagues in the Molecular Microbiology Research Unit which is why this is important.
For more information about this position and project, please contact Dr Lin Lin, [email protected].
Reference papers:
Lin, L., Capozzoli, R., Ferrand, A., Plum. M., Vettiger. A., & Basler, M. (2022) Subcellular localization of Type VI secretion system assembly in response to cell-cell contact. EMBO J, 41(13):e108595.
Lin, L., Ringel, P., Vettiger, A., Dürr, L., & Basler, M. (2019) DNA uptake upon T6SS-dependent prey cell lysis induces SOS response and reduces fitness of Acinetobacter baylyi. Cell Reports 29(6):1633-1644.e4.
Lin L., Lezan, E., Schmidt, A., & Basler, M. (2019) Abundance of bacterial Type VI secretion system components measured by targeted proteomics. Nature Communications 10, 2584.
Application, salary etc.
Appointment as a PhD Research Fellow is for three years. Employment stops automatically at the end of the period. The holder of the scholarship is not allowed to have other paid employment during the three-year period.
The successful applicant will be employed in accordance with the agreement on salaried PhD scholars between the Ministry of Finance and AC (the Danish Confederation of Professional Associations). Please check links for more information on salary and taxation.
The successful candidate will be enrolled at this university in accordance with faculty regulations and the Danish Ministerial Order on the PhD Programme at the Universities (PhD order).
The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.
Application must be in English and made in the form of a Declaration of Interest including the following:
• A research proposal/description of your approach to the above project (max one page excluding references)
• A letter stating your specific interest, motivation and qualifications for the project in question (max. two pages) (please attach this under box "Application form")
• Detailed CV, including personal contact information
• Copies of diplomas, Bachelor as well as Master’s degree, including transcript of notes/grades
• At least two signed reference letters. Should your referees wish to send their letters directly to us, please have them use e-mail: [email protected] mentioning your name and the title of the position in the subject line. And please note that these also need to reach us before deadline.
Shortlisting may be used in the assessment process.
Further information about the PhD-study can be found at the homepage of the University.
Applications must be submitted electronically using the link "Apply online". Attached files must be in Adobe PDF or Word format. Each box can only contain a single file of max. 10 Mb. We strongly recommend that you read How to apply before you apply.
Incomplete applications and applications received after the deadline will neither be considered nor evaluated. This also applies to reference letters.
Further information for international applicants about entering and working in Denmark.
Information og data
Denne ledige stilling har jobtypen "Forsker", og befinder sig i kategorien "Sundhed og forskning".
Arbejdsstedet er beliggende i Odense M.
Jobbet er oprettet på vores service den 15.12.2022, men kan have været deaktiveret og genaktiveret igen.
Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
- Forsker
- Odense M
- Tirsdag den 31. januar 2023
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