Analytical Technician – Early Phase Biopharmaceutical Products

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Ballerup

A chance to be part of an ambiguous and flexible laboratory group in LEO CMC area



LEO Pharma has embarked on a growth journey to become the preferred dermatology care partner in the world, dedicated to help people achieve healthy skin. We have an ambitious 2030 strategy, which aims to accelerate our impact in protein-based therapeutics while strengthening our established portfolio and our global footprint in medical dermatology. Dermatology is an area of rapid growth and LEO Pharma´s vision is to help people with mild, moderate and severe dermatological diseases across the world. To meet the requirements of an increasing pipeline of biologics projects we are now expanding in the CMC biologics area both in terms of capabilities and capacity. This is why we need you!


Biopharmaceutical analysis (early phase)


Your overall focus will be screening, characterization and analysis of monoclonal antibodies (mAbs) in close collaboration with formulation and analytical scientists to support our early phase lab activities. You will be responsible for sample preparation, developing analytical methods, maintaining analytical equipment, write analytical procedures, data analysis of your own experiments and documenting the data and results in ELN. You will be working with the team to deliver high quality results for the projects in early phase development, and you will also work with colleagues from the bioprocess and product departments.

Your primary tasks

  • Protein analyses by different UPLC methods (e.g. CIEX and SEC), CIEF, CE-SDS as well as biophysical characterization by DLS, DSF and viscometry.
  • Method development and forced degradation studies
  • Handling of large number of protein samples: For formulation screening studies, developability assessment of mAb variants, and for in vivo testing.
  • Organizing and setting up stability studies according to protocol, as well as conducting the concomitant protein stability analyses
  • Maintain a balance between experimental work, data treatment and solid documentation
  • Take part in troubleshooting using the joined analytical knowledge of the early phase group

As we are breaking new ground and are part of an R&D organisation, no two days are alike. As such, you must be able to thrive in a dynamic R&D environment and have the drive and entrepreneurial spirit to move things ahead.

+3 years’ experience within protein analysis


You have an education as Laboratory Technician or similar with at least 3 years’ experience in protein analysis and characterization. You favour experimental work and your career has provided you with hands-on experience with development of analytical methods for proteins (e.g. mAbs of different formats). You can work independently and are used to solve day-to-day laboratory tasks . You have worked with and have an interest in new technologies in the analytical area and have flair for equipment and problem solving.

You are curious by nature and like to try new things, methods, processes etc. You combine strong bench skills with a good sense for documentation to ensure clear communication of experimental work and data. As you will work together with multiple people across the LEO organisation, good collaboration skills are of great importance.

Biopharm Analytical Development – your new department


You will join a team of eight (today) skilled colleagues covering early phase biopharmaceutical competencies. We are a growing team, and our focus is to support selection of stable mAbs and development of stabilizing formulations for LEO Pharma’s portfolio of biologics. We aim to establish an innovation culture characterised by openness, plenty of room for new ideas, mutual respect and helpfulness – while not forgetting to have a good time together. The department is part of Biopharmaceutical CMC Development 25+ highly skilled and dedicated colleagues striving to deliver high quality science to progress our Research and Development projects and to deliver innovative products to patients.
We are here to take ownership, drive, and secure that scientific questions are both raised and answered within Biologics. We are driven by a high level of integrity, science, passion for our work and an open minded, collaborative approach.

The position is placed in the LEO Pharma headquarters in Ballerup.

We look forward to receiving your application in English or Danish not later than 15th of August 2021. If you need further information please contact Christer Andersson, Senior Manager of Biopharm Analytical Development (+45 31 38 59 86) or Lars Dencker Principal Analytical Scientist (+45 72 26 36 05) or Heidi Westh Bagger Principal Analytical Scientist (+45 22 45 35 82).


Information og data

Denne ledige stilling har jobtypen "Kemiker", og befinder sig i kategorien "Sundhed og forskning".

Arbejdsstedet er beliggende i Ballerup.

Jobbet er oprettet på vores service den 4.7.2021, men kan have været deaktiveret og genaktiveret igen.

Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
  • Kemiker
  • Ballerup
  • Søndag den 15. august 2021

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