Sr. / Pr. Scientist – Immunology
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Ballerup
Dragonfly Therapeutics – DK is seeking an experienced scientist to be responsible for developing in vitro assays and apply these to advance our drug candidates in inflammatory, autoimmune and fibrotic diseases.
With a background in NK cells and immunology and expertise in in vitro assays, the successful candidate will be responsible for driving biology in our partnered programs, which includes setting up relevant assays for proof-of-mechanism work and screening of candidates and delivery of opt-in biology package to our partners. The candidate will work closely together with the Biologics Lead, Alliance Manager, and cross-functional teams to drive the programs forward. The job will include guiding technicians and do own lab work to set up assays including culture of primary immune cells such as NK cells, T cells and fibroblasts, establishment of binding and killing assays, and measurements of relevant readouts by e.g. imaging, flow cytometry or Luminex. Establishment and conduct of in vivo mouse models to support PKPD of our molecules may also be part of the job depending on the incumbent’s qualifications. With reference line to Kresten Skak, head of inflammation, the position is an add-on to our Dragonfly biology team in Copenhagen, Denmark. Title and responsibility will be adapted to the experience of the final candidate.
Responsibilities
Qualifications
About Dragonfly
Founded in late 2015 by Dr. Tyler Jacks (founding director of the Koch Institute at MIT), Dr. David Raulet (one of the world's leading experts in Natural Killer (NK) cell biology), and Bill Haney (a longtime tech entrepreneur and investor), Dragonfly Therapeutics was launched to harness the power of the immune system to provide breakthrough treatments for patients – especially in areas where there are no effective therapies.
The company develops novel first-in-class therapeutics designed to harness Natural Killer cells and other cells of the innate immune system which can provide direct killing of disease promoting cell types and provide a unique therapeutic window beyond current therapies for treatment of cancer and chronic inflammatory diseases.
Our mission is to revolutionize disease treatment by inventing natural killer cell-based therapies for vastly improved patient outcomes. We believe in a small team with a big impact.
Please visit our website for details.
We offer
Our employees are fundamental to our success, and we continue to be able to attract and retain people with different experiences and backgrounds. We have a high-performing, collaborative culture characterized by respectful and diverse teams who are committed to our patients first mission.
At Dragonfly, you will have the opportunity to have impact, work with some of the brightest minds in the industry, develop your professional career, and contribute to breakthrough medicines for patients with urgent unmet medical needs.
Your application
You can apply for the position by sending a cover letter and resume, using the button "Apply/Send ansøgning".
We are screening and interviewing for the position on an ongoing basis and it would be an advantage to apply as soon as possible, no later than June 1st.
For any further questions please email [email protected]
For more info, check out our career site https://dragonflytx.ofir.com
Denne jobannonce blev oprindeligt opslået på
(Den originale annonce kan ses på: )
Kilde: Jobnet.dk
With a background in NK cells and immunology and expertise in in vitro assays, the successful candidate will be responsible for driving biology in our partnered programs, which includes setting up relevant assays for proof-of-mechanism work and screening of candidates and delivery of opt-in biology package to our partners. The candidate will work closely together with the Biologics Lead, Alliance Manager, and cross-functional teams to drive the programs forward. The job will include guiding technicians and do own lab work to set up assays including culture of primary immune cells such as NK cells, T cells and fibroblasts, establishment of binding and killing assays, and measurements of relevant readouts by e.g. imaging, flow cytometry or Luminex. Establishment and conduct of in vivo mouse models to support PKPD of our molecules may also be part of the job depending on the incumbent’s qualifications. With reference line to Kresten Skak, head of inflammation, the position is an add-on to our Dragonfly biology team in Copenhagen, Denmark. Title and responsibility will be adapted to the experience of the final candidate.
Responsibilities
- Serve as primary Biology representative or lead, working cross-functionally with counterparts towards program deliverables.
- Design and perform in vitro biology studies to advance our growing pipeline.
- Isolate, culture, and set up functional assays using human primary immune cells, fibroblasts, and NK cells through research associates and own lab work.
- Independently plan, perform, analyze, interpretate and report results in a timely manner.
- Train research associates in new in vitro assays.
- Interface with CROs for relevant support when in-house expertise or resources are lacking.
- Generate, manage, analyze, and maintain critical data with integrity and in a highly organized manner;
- Document data in electronic laboratory notebook and write technical reports.
- Work collaboratively within the Dragonfly Team.
Qualifications
- Ph.D. degree in Immunology, Cell Biology or related area with a strong background in inflammatory, autoimmune and/or fibrotic diseases. Experience with NK cells is highly preferred.
- At least 3-6 years of relevant experience post-PhD, preferably with drug discovery and target validation experience from biotech/pharma.
- Hands-on experience with standard immunology techniques including primary cell isolation and culture, ELISA, cytotoxicity assays, cellular imaging and flow cytometry is required.
- Experience with experimental animal models is an advantage.
- A deep understanding the immune system including knowledge of immune-mediated inflammatory disorders is highly desirable.
- Experience with therapeutic and bispecific antibodies is an advantage.
- Experience working with CROs and vendors is preferred.
- Efficient time management and ability to work on several projects simultaneously.
- Strong interpersonal skills and ability to effectively communicate with members of a multidisciplinary team.
- Ability to work collaboratively, provide scientific insight, and communicate clearly in writing and orally.
- Excellent record keeping abilities to document analytical data generated in support of regulatory requirements.
- A flexible mindset with the ability to adapt to a rapidly changing environment in a fastgrowing start-up.
About Dragonfly
Founded in late 2015 by Dr. Tyler Jacks (founding director of the Koch Institute at MIT), Dr. David Raulet (one of the world's leading experts in Natural Killer (NK) cell biology), and Bill Haney (a longtime tech entrepreneur and investor), Dragonfly Therapeutics was launched to harness the power of the immune system to provide breakthrough treatments for patients – especially in areas where there are no effective therapies.
The company develops novel first-in-class therapeutics designed to harness Natural Killer cells and other cells of the innate immune system which can provide direct killing of disease promoting cell types and provide a unique therapeutic window beyond current therapies for treatment of cancer and chronic inflammatory diseases.
Our mission is to revolutionize disease treatment by inventing natural killer cell-based therapies for vastly improved patient outcomes. We believe in a small team with a big impact.
Please visit our website for details.
We offer
Our employees are fundamental to our success, and we continue to be able to attract and retain people with different experiences and backgrounds. We have a high-performing, collaborative culture characterized by respectful and diverse teams who are committed to our patients first mission.
At Dragonfly, you will have the opportunity to have impact, work with some of the brightest minds in the industry, develop your professional career, and contribute to breakthrough medicines for patients with urgent unmet medical needs.
Your application
You can apply for the position by sending a cover letter and resume, using the button "Apply/Send ansøgning".
We are screening and interviewing for the position on an ongoing basis and it would be an advantage to apply as soon as possible, no later than June 1st.
For any further questions please email [email protected]
For more info, check out our career site https://dragonflytx.ofir.com
Denne jobannonce blev oprindeligt opslået på
(Den originale annonce kan ses på: )
Kilde: Jobnet.dk
Information og data
Denne ledige stilling har jobtypen "Kemiker", og befinder sig i kategorien "Sundhed og forskning".
Arbejdsstedet er beliggende i Ballerup.
Jobbet er oprettet på vores service den 14.5.2022, men kan have været deaktiveret og genaktiveret igen.
Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
- Kemiker
- Ballerup
- Onsdag den 01. juni 2022
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