Research Scientist – Analytical Peptide Chemist
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Hørsholm
Are you eager to use your scientific skills and analytical expertise in preclinical research? Are you an experienced analytical chemist with a flair for mass spectroscopy and HPLC analysis? Are you motivated by working in a multi-disciplinary environment? If so, we have an exciting opportunity for you at Gubra. We are looking for a scientist to join our Chemistry and Bioanalysis department. You will be responsible for the analytical workflows relating to our peptide chemistry workflow, such as concentration and purity determination, as well as supporting our skilled technicians in the laboratory with operation and maintenance of analytical machinery.
The Chemistry and Bioanalysis department supports our business by driving our finely tuned peptide drug discovery platform, streaMLine, by performing high-throughput peptide synthesis and providing high quality data for our discovery projects. At Gubra we strive to work smart and consequently seek to automate manual tasks, thereby liberating resources for innovation and scientific challenges. In the chemistry and bioanalysis group, we work closely together with the AI Technology group to utilize data generated in our streaMLine platform to accelerate drug discovery. We excel in automated SPPS, peptide purification and characterization, as well as peptide bioanalysis and metabolite identification by LC-MS/MS. You will join an interdisciplinary team of 7 scientists and 7 laboratory technicians who collaborate across the whole value chain of drug discovery in both internal and contract research drug discovery assignments. The department is part of an area comprising molecular pharmacology and biomarker assays as well as pharmaceutical profiling and formulation.
As our new scientist, your tasks will include:
Professional qualifications:
As a person you:
Please apply no later than June 23th, 2023 by uploading your motivated cover letter, CV and relevant diplomas on our website. Note that applications will be reviewed on an ongoing basis. If you have questions about the position, please contact Pernille Tofteng Shelton, Senior Department Manager at [email protected]
About Gubra
Gubra is an ambitious and innovative biotech company striving for excellence at all levels. We insist on doing things efficiently – and often differently - to reach the results we aim for. Our vision is to become leaders in the fight for a more sustainable and healthier world. We do that by facilitating the discovery of new medicine, and by acting and inspiring others to fight against the ongoing climate and biodiversity crises.
We have two primary areas of business: Preclinical contract research (CRO) services, and Proprietary early target and drug discovery programs. We are a biotech company delivering science to our partners and to our own research projects. We are active in the so-called pre-clinical space - before drugs are tested in humans - and generate our revenue by performing research for small and large pharma companies.
Our focus is within the metabolic space (obesity, diabetes, NASH (Non-alcoholic steatohepatitis), and diabetic complications), where we specialize in in vivo pharmacology, peptide chemistry, molecular pharmacology, histology, stereology, imaging, NGS (next generation sequencing), bioinformatics and biomarker assays. We work with some of the most interesting and loyal partners and customers from across the world within big pharma, biotech, and academia. Through a constant focus on high quality, scientific excellence, speed, and solid teamwork we have established ourselves as a highly professional and competent partner in the market.
People are our greatest asset, and our team consists of +200 employees all located in Hørsholm, Denmark. The mix of people from different cultures and educational backgrounds combined with our entrepreneurial mindset have greatly impacted our working environment, which is characterized by intensive drive, scientific curiosity, and teamwork – we join forces!
The Chemistry and Bioanalysis department supports our business by driving our finely tuned peptide drug discovery platform, streaMLine, by performing high-throughput peptide synthesis and providing high quality data for our discovery projects. At Gubra we strive to work smart and consequently seek to automate manual tasks, thereby liberating resources for innovation and scientific challenges. In the chemistry and bioanalysis group, we work closely together with the AI Technology group to utilize data generated in our streaMLine platform to accelerate drug discovery. We excel in automated SPPS, peptide purification and characterization, as well as peptide bioanalysis and metabolite identification by LC-MS/MS. You will join an interdisciplinary team of 7 scientists and 7 laboratory technicians who collaborate across the whole value chain of drug discovery in both internal and contract research drug discovery assignments. The department is part of an area comprising molecular pharmacology and biomarker assays as well as pharmaceutical profiling and formulation.
As our new scientist, your tasks will include:
- Contributing to our internal drug discovery projects with analytical data such as peptide purity and concentration determination.
- Troubleshooting peptide synthesis through by-product analysis.
- Advancing digital solutions for documentation, sample- and data analysis workflows.
- Taking the lead in implementing automated analytical solutions.
- Operation, troubleshooting and maintenance of analytical equipment such as HPLC, LC-MS, LC-CAD and LC-MS(MS).
- Planning and coordinating and executing experiments in collaboration with lab technicians.
Professional qualifications:
- A life science background preferably at PhD level within analytical chemistry and/or peptide chemistry.
- Extensive hands-on experience with various methods for (quantitative) peptide analysis (HPLC and LC-MS).
- Preferably, a knowledge of LC-CAD and peptide quantification.
- Knowledge of programming and scripting in R and/or Python including user interfacing is an advantage.
- Are used to communicating in English (oral and written)
As a person you:
- Are self-motivated and able to navigate and collaborate well in an energetic organization.
- Are structured and comfortable working with deadlines.
- Have strong analytical skills and enjoy scientific challenges.
- Enjoy a workday that includes practical work in the lab as well as data analysis.
- Keen to take on responsibility within own area of expertise.
Please apply no later than June 23th, 2023 by uploading your motivated cover letter, CV and relevant diplomas on our website. Note that applications will be reviewed on an ongoing basis. If you have questions about the position, please contact Pernille Tofteng Shelton, Senior Department Manager at [email protected]
About Gubra
Gubra is an ambitious and innovative biotech company striving for excellence at all levels. We insist on doing things efficiently – and often differently - to reach the results we aim for. Our vision is to become leaders in the fight for a more sustainable and healthier world. We do that by facilitating the discovery of new medicine, and by acting and inspiring others to fight against the ongoing climate and biodiversity crises.
We have two primary areas of business: Preclinical contract research (CRO) services, and Proprietary early target and drug discovery programs. We are a biotech company delivering science to our partners and to our own research projects. We are active in the so-called pre-clinical space - before drugs are tested in humans - and generate our revenue by performing research for small and large pharma companies.
Our focus is within the metabolic space (obesity, diabetes, NASH (Non-alcoholic steatohepatitis), and diabetic complications), where we specialize in in vivo pharmacology, peptide chemistry, molecular pharmacology, histology, stereology, imaging, NGS (next generation sequencing), bioinformatics and biomarker assays. We work with some of the most interesting and loyal partners and customers from across the world within big pharma, biotech, and academia. Through a constant focus on high quality, scientific excellence, speed, and solid teamwork we have established ourselves as a highly professional and competent partner in the market.
People are our greatest asset, and our team consists of +200 employees all located in Hørsholm, Denmark. The mix of people from different cultures and educational backgrounds combined with our entrepreneurial mindset have greatly impacted our working environment, which is characterized by intensive drive, scientific curiosity, and teamwork – we join forces!
Information og data
Denne ledige stilling har jobtypen "Laborant", og befinder sig i kategorien "Sundhed og forskning".
Arbejdsstedet er beliggende i Hørsholm.
Jobbet er oprettet på vores service den 9.6.2023, men kan have været deaktiveret og genaktiveret igen.
Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
- Laborant
- Hørsholm
- Fredag den 23. juni 2023
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