PhD Project in Phage Biology and Bacterial Immunity
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Frederiksberg C
PhD Project in Phage Biology and Bacterial Immunity
Biology
Faculty of SCIENCE
University of Copenhagen
The Department of Biology, Section of Microbiology invites applicants for a PhD fellowship in Microbiology. The project is part of the research project “DISCOVIR: DISCOvery of anti-VIRal immune strategies in bacteria”, financed by a Villum Young Investigator grant.
Start date is expected to be December 1st 2024, or as soon as possible thereafter.
The project
Phages are ubiquitous viruses that infect and kill bacteria. As a result, bacteria have evolved diverse anti-phage defense systems to protect themselves from infection, but the extent of the diversity of defense systems across environments and their molecular mechanisms remains largely unexplored. The position is part of a project funded by a Villum Young Investigator grant (Villum Fonden), which seeks to shed light on the co-evolution of phages and bacteria. This research is expected to enhance our understanding of bacterial immunity and could lead to advances in biotechnological applications, treatments for antibiotic-resistant infections, and models for studying immunity in humans and other organisms.
The selected candidate will conduct research in the Bacterial Immunity group led by Asst. Prof. Rafael Pinilla-Redondo at the Section of Microbiology, University of Copenhagen, in collaboration with Prof. Peter Fineran’s group at the University of Otago, Dunedin, New Zealand. Responsibilities include engaging in advanced microbiology/molecular biology research and teaching/supervising students at the University of Copenhagen.
Who are we looking for?
Applicants should hold a MSc or equivalent degree in biology, biotechnology, microbiology, molecular biology, or a related field. Experience in phage biology, bacterial anti-phage defense mechanisms, and bioinformatics is highly preferred. In addition, the successful applicant will demonstrate:
Our group and research- and what do we offer?
The Bacterial Immunity Group at the University of Copenhagen is a dynamic and emerging research team within the Section of Microbiology, Department of Biology, Faculty of SCIENCE, located in the North Campus at KU (Universitetsparken 15, 2100 København). We are a close-knit team of 5-8 passionate researchers, with half of the team dedicated to wet lab work and the other focused on bioinformatics. Despite being a relatively new group, we stand out for our strong international research network and the impactful contributions we’ve already made to the field of bacterial immunity, including the discovery of the 1st RNA-based anti-CRISPRs (Racrs) 1, the discovery and characterization of plasmid-encoded type IV CRISPR-Cas systems 2, and the characterization of Retron anti-phage defense systems 3. We place a high value on frequent social activities and building international collaborations, offering a creative and stimulating environment that embraces diversity, with access to state-of-the-art microbiology laboratories and cutting-edge computational infrastructure.
Contact: Principal supervisor is Asst. Prof. Rafael Pinilla-Redondo, Dept. Biology, Section of Microbiology, [email protected].
********************************************************************************
Option A: Getting into a position on the regular PhD programme
Qualifications needed for the regular programme
To be eligible for the regular PhD programme, you must have completed a degree programme, equivalent to a Danish master’s degree (180 ECTS/3 FTE BSc + 120 ECTS/2 FTE MSc) related to the subject area of the project, e.g. Biology, Microbiology, Immunology, Biochemistry, or a related field. For information on eligibility of completed programmes, see General assessments for specific countries and Assessment database.
Terms of employment in the regular programme
Employment as PhD fellow is full time and for maximum 3 years.
Employment is conditional upon your successful enrolment as a PhD student at the PhD School at the Faculty of SCIENCE, University of Copenhagen. This requires submission and acceptance of an application for the specific project formulated by the applicant.
Terms of appointment and payment accord to the agreement between the Danish Ministry of Taxation and The Danish Confederation of Professional Associations on Academics in the State. The position is covered by the Protocol on Job Structure.
Responsibilities and tasks for PhD programmes
We are looking for the following qualifications:
***************************************************************************
Application and Assessment Procedure
Your application including all attachments must be in English and submitted electronically by clicking APPLY NOW below.
Please include:
Application deadline:
The deadline for applications is 15.09.2024 23:59 GMT +1
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
The further process
After deadline, a number of applicants will be selected for academic assessment by an unbiased expert assessor. You are notified, whether you will be passed for assessment.
The assessor will assess the qualifications and experience of the shortlisted applicants with respect to the above mentioned research area, techniques, skills and other requirements. The assessor will conclude whether each applicant is qualified and, if so, for which of the two models. The assessed applicants will have the opportunity to comment on their assessment. You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/.
Interviews with selected candidates are expected to be held in week 39
Questions
For specific information about the PhD fellowship, please contact the principal supervisor.
General information about PhD study at the Faculty of SCIENCE is available at the PhD School’s website: https://www.science.ku.dk/phd/.
The University of Copenhagen wishes to reflect the surrounding community and invites all regardless of personal background to apply for the position.
Kilde: Jobnet.dk
Biology
Faculty of SCIENCE
University of Copenhagen
The Department of Biology, Section of Microbiology invites applicants for a PhD fellowship in Microbiology. The project is part of the research project “DISCOVIR: DISCOvery of anti-VIRal immune strategies in bacteria”, financed by a Villum Young Investigator grant.
Start date is expected to be December 1st 2024, or as soon as possible thereafter.
The project
Phages are ubiquitous viruses that infect and kill bacteria. As a result, bacteria have evolved diverse anti-phage defense systems to protect themselves from infection, but the extent of the diversity of defense systems across environments and their molecular mechanisms remains largely unexplored. The position is part of a project funded by a Villum Young Investigator grant (Villum Fonden), which seeks to shed light on the co-evolution of phages and bacteria. This research is expected to enhance our understanding of bacterial immunity and could lead to advances in biotechnological applications, treatments for antibiotic-resistant infections, and models for studying immunity in humans and other organisms.
The selected candidate will conduct research in the Bacterial Immunity group led by Asst. Prof. Rafael Pinilla-Redondo at the Section of Microbiology, University of Copenhagen, in collaboration with Prof. Peter Fineran’s group at the University of Otago, Dunedin, New Zealand. Responsibilities include engaging in advanced microbiology/molecular biology research and teaching/supervising students at the University of Copenhagen.
Who are we looking for?
Applicants should hold a MSc or equivalent degree in biology, biotechnology, microbiology, molecular biology, or a related field. Experience in phage biology, bacterial anti-phage defense mechanisms, and bioinformatics is highly preferred. In addition, the successful applicant will demonstrate:
- Experience in routine microbiology practices (bacterial culture, DNA extraction, PCR, etc.).
- Experience with cloning genes, plasmid preps, and sequencing.
- Experience preparing phage stocks and performing infection assays.
- Advanced knowledge in phage biology and bacterial immunity.
- Enthusiasm for interdisciplinary research and teaching.
- Experience or interest in bioinformatics analyses.
- Excellent teamwork and interpersonal skills, and possess a collaborative and open mindset.
- Willingness to engage in group social activities.
- Excellent English skills written and spoken.
Our group and research- and what do we offer?
The Bacterial Immunity Group at the University of Copenhagen is a dynamic and emerging research team within the Section of Microbiology, Department of Biology, Faculty of SCIENCE, located in the North Campus at KU (Universitetsparken 15, 2100 København). We are a close-knit team of 5-8 passionate researchers, with half of the team dedicated to wet lab work and the other focused on bioinformatics. Despite being a relatively new group, we stand out for our strong international research network and the impactful contributions we’ve already made to the field of bacterial immunity, including the discovery of the 1st RNA-based anti-CRISPRs (Racrs) 1, the discovery and characterization of plasmid-encoded type IV CRISPR-Cas systems 2, and the characterization of Retron anti-phage defense systems 3. We place a high value on frequent social activities and building international collaborations, offering a creative and stimulating environment that embraces diversity, with access to state-of-the-art microbiology laboratories and cutting-edge computational infrastructure.
- Camara-Wilpert S, Mayo-Muñoz D, Russel J, et al. Bacteriophages suppress CRISPR-Cas immunity using RNA-based anti-CRISPRs. Nature. 2023;623(7987):601-607. doi:10.1038/s41586-023-06612-5
- Benz F, Camara-Wilpert S, Russel J, et al. Type IV-A3 CRISPR-Cas systems drive inter-plasmid conflicts by acquiring spacers in trans. Cell Host Microbe. 2024;32(6):875-886.e9. doi:10.1016/j.chom.2024.04.016
- Carabias A, Camara-Wilpert S, Mestre MR, et al. Retron-Eco1 assembles NAD+-hydrolyzing filaments that provide immunity against bacteriophages. Mol Cell. 2024;84(11):2185-2202.e12. doi:10.1016/j.molcel.2024.05.001
Contact: Principal supervisor is Asst. Prof. Rafael Pinilla-Redondo, Dept. Biology, Section of Microbiology, [email protected].
********************************************************************************
Option A: Getting into a position on the regular PhD programme
Qualifications needed for the regular programme
To be eligible for the regular PhD programme, you must have completed a degree programme, equivalent to a Danish master’s degree (180 ECTS/3 FTE BSc + 120 ECTS/2 FTE MSc) related to the subject area of the project, e.g. Biology, Microbiology, Immunology, Biochemistry, or a related field. For information on eligibility of completed programmes, see General assessments for specific countries and Assessment database.
Terms of employment in the regular programme
Employment as PhD fellow is full time and for maximum 3 years.
Employment is conditional upon your successful enrolment as a PhD student at the PhD School at the Faculty of SCIENCE, University of Copenhagen. This requires submission and acceptance of an application for the specific project formulated by the applicant.
Terms of appointment and payment accord to the agreement between the Danish Ministry of Taxation and The Danish Confederation of Professional Associations on Academics in the State. The position is covered by the Protocol on Job Structure.
Responsibilities and tasks for PhD programmes
- Complete and pass the MSc education in accordance with the curriculum of the MSc programme
- Carry through an independent research project under supervision
- Complete PhD courses corresponding to approx. 30 ECTS / ½ FTE
- Participate in active research environments, including a stay at another research institution, preferably abroad
- Teaching and knowledge dissemination activities
- Write scientific papers aimed at high-impact journals
- Write and defend a PhD thesis on the basis of your project
We are looking for the following qualifications:
- Experience in routine microbiology practices (bacterial culture, DNA extraction, PCR, etc.).
- Experience with cloning genes, plasmid preps, and sequencing.
- Experience preparing phage stocks and performing infection assays.
- Enthusiasm for interdisciplinary research and teaching.
- Experience or interest in bioinformatics analyses
- Excellent teamwork and interpersonal skills, and possess a collaborative and open mindset.
- Excellent English skills written and spoken.
***************************************************************************
Application and Assessment Procedure
Your application including all attachments must be in English and submitted electronically by clicking APPLY NOW below.
Please include:
- Motivated letter of application (max. one page)
- Curriculum vitae including information about your education, experience, language skills, and other skills relevant to the position
- Original diplomas for Bachelor of Science or Master of Science and transcript of records in the original language, including an authorized English translation if issued in another language than English or Danish. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor is accepted.
- Publication list (if relevant)
- Reference letters (if available)
Application deadline:
The deadline for applications is 15.09.2024 23:59 GMT +1
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
The further process
After deadline, a number of applicants will be selected for academic assessment by an unbiased expert assessor. You are notified, whether you will be passed for assessment.
The assessor will assess the qualifications and experience of the shortlisted applicants with respect to the above mentioned research area, techniques, skills and other requirements. The assessor will conclude whether each applicant is qualified and, if so, for which of the two models. The assessed applicants will have the opportunity to comment on their assessment. You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/.
Interviews with selected candidates are expected to be held in week 39
Questions
For specific information about the PhD fellowship, please contact the principal supervisor.
General information about PhD study at the Faculty of SCIENCE is available at the PhD School’s website: https://www.science.ku.dk/phd/.
The University of Copenhagen wishes to reflect the surrounding community and invites all regardless of personal background to apply for the position.
Kilde: Jobnet.dk
Information og data
Denne ledige stilling har jobtypen "Øvrige", og befinder sig i kategorien "Øvrige stillinger".
Arbejdsstedet er beliggende i Frederiksberg C.
Jobbet er oprettet på vores service den 28.8.2024, men kan have været deaktiveret og genaktiveret igen.
Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
- Øvrige
- Frederiksberg C
- Søndag den 15. september 2024
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