Scientist for mass spectrometry bioanalysis and profiling of peptide therapeutics

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Hørsholm

Gubra is looking for a Scientist to support our peptide drug discovery pipeline as well as advanced contract research assignments within bioanalysis and pharmaceutical research.

Gubra is an ambitious biotech company striving for excellence at all levels. We insist on doing things efficiently – and often differently - to reach the results we aim for. Our vision is to become leaders in the fight for a more sustainable and healthier world. We do that by facilitating the discovery of new medicines, and by acting and inspiring others to fight against the ongoing climate and biodiversity crises.

You are technologically savvy, inventive and flexible and you value collaboration with your skilled colleagues. You want to work for a purpose driven company, where you can develop while handling varied tasks in multidisciplinary teams.

As Scientist in mass spectrometry bioanalysis you will:

Contribute to

  • Methods for quantification of peptides and small molecules in LC-MS/MS
  • Optimal sample preparation including online Transcend Turboflow
  • Troubleshooting and maintenance of equipment performance
  • Peptide and formulation testing in RP-UPLC systems
  • Deliveries of PK, drug exposure, metabolite, and stability data to internal/partnered projects and customers

Develop

  • Our bioanalysis and RP-UPLC platform, including technologies and automation
  • Digital solutions - in close collaboration with our computational biologists - for sample- and data flow
  • Drug discovery project opportunities
  • Collaboration, innovation, and documentation

You will be working closely with technicians and scientists in the Drug Preparation and Profiling Group. The group consists of 10 technicians and 5 scientists. It is part of the In vitro & Pharmaceutical Research Area responsible for bioanalysis and biomarker assays, pharmaceutical and in vitro cellular characterisation of peptide drug candidates, formulation expertise and next generation RNA sequencing.

Professional qualifications

  • PhD degree and/or relevant experience in analytical chemistry/biochemistry and
  • Hands-on experience with plasma bioanalysis, mass spectrometry and assay optimisation on several LC-MS/MS platforms
  • A desire to develop as an expert in mass spectrometry and RP-UPLC
  • DMPK experience incl. PK/PD modelling is an advantage
  • Experience with accurate mass analysis and proteomics is an advantage


As person you are

  • Keen to take on responsibility within your area of expertise
  • Curious by nature, motivated by data and not afraid of technical challenges
  • Proactive and able to initiate, focus and deliver on tasks and projects
  • Able to navigate and collaborate in an energetic and rapidly changing organization


Please apply no later than 29. November 2020 by uploading your motivated cover letter and resume on our website. Applications will be reviewed as received.

If you have questions about the position, please contact Lisbeth Fink, Area Head at +45 6127 6672.

About Gubra 
Gubra is a company with a very dynamic and fast-paced drive. We have two primary areas of business: Preclinical contract research (CRO) services, and Proprietary early target and drug discovery programs.

We are a biotech company delivering science to our partners and to our own research projects. We are active in the so-called pre-clinical space - before drugs are tested in humans - and generate a revenue by performing research for small and large pharma companies. 

Our focus is within the metabolic space (obesity, diabetes, NASH and diabetic complications), where we specialize in in vivo pharmacology, peptide chemistry, molecular pharmacology, histology, stereology, imaging, NGS (next generation sequencing), bioinformatics and assays. We work with some of the most interesting and loyal partners and customers from across the world within big pharma, biotech and academia. Through a constant focus on high quality, scientific excellence, speed and solid teamwork we have established ourselves as a highly professional and competent partner in the market.

People are our greatest asset, and our team consists of +150 employees all located in Hørsholm, Denmark. The mix of people from different cultures and educational backgrounds combined with our entrepreneurial mindset have greatly impacted our working environment, which is characterized by intensive drive, scientific curiosity, and teamwork – we join forces!


Information og data

Denne ledige stilling har jobtypen "Forsker", og befinder sig i kategorien "Sundhed og forskning".

Arbejdsstedet er beliggende i Hørsholm.

Jobbet er oprettet på vores service den 10.11.2020, men kan have været deaktiveret og genaktiveret igen.

Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
  • Forsker
  • Hørsholm
  • Søndag den 29. november 2020

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