Postdoc in medicinal chemistry and in vivo pharmacology at the Novo Nordisk Foundation Center for Basic Metabolic Res...

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København N

The Faculty of Health and Medical Sciences
University of Copenhagen


The University of Copenhagen is seeking an experienced Postdoc fellow to commence on 15 November 2023, or after agreement, for the Clemmensen Group at the Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR), University of Copenhagen.

About Us
The Novo Nordisk Foundation Center for Basic Metabolic Research’s vision is to pioneer groundbreaking research towards better cardiometabolic health. We wish to lead collaborative interdisciplinary research from single-cell genomics to whole-body systems, transforming the basic understanding of cardiometabolic health, and accelerating its translation into prevention and treatment strategies. We were established in 2010, and in 2017, we moved into new laboratories, offices, and meeting rooms in the Maersk Tower www.maersktower.ku.dk.

The Center has around 260 employees who work in an international, highly collaborative research environment across a range of biomedical disciplines. You can read more about us here: www.cbmr.ku.dk.

Our Research
The Clemmensen Group studies the biological regulation of body weight and aims at developing new therapeutic strategies that can correct obesity and its metabolic comorbidities. Inspired and encouraged by our research in energy balance and neuroscience, we employ medicinal chemistry to engineer new drug candidates for the treatment of obesity and obesity-associated diseases. We utilize modified peptide hormones to deliver small molecules of interest to target cells, with the long-term aspiration to create new drugs that will lower the defended level of body fat.

Job Description
The growing obesity epidemic has escalated the progression of a series of non-communicable diseases, including type 2 diabetes and non-alcoholic steatohepatitis (NASH). While efficient pharmacotherapies are in development for these disorders, an unmet need remains and there is urgent need for innovative basic research paving the way for new drugs. This current project will explore novel peptides and small molecule drug candidates for treatment of metabolic disease and will both involve design and synthesis of compounds as well as in vitro and in vivo testing in preclinical models.

Profile
We are looking for a highly motivated and enthusiastic scientist with the following competencies and experience:

Required qualifications:

  • PhD in Pharmacology, Biochemistry, Chemistry, Molecular Biomedicine, or related sciences
  • Excellent scientific track record (i.e., publications, training) in relation to career stage
  • Profound knowledge on pharmacology, especially drug testing in preclinical obesity models
  • Profound experience with synthetic chemistry, drug development, structure-activity relationship
  • Knowledge on basic substrate metabolism and metabolic diseases, including obesity, type 2 diabetes and liver disease (e.g. NAFLD, NASH)
  • A curious and innovative mindset with strong self-motivation to develop new knowledge and treatment for complex cardiometabolic disease
  • Excellent English communication skills, both written and oral

Terms of Employment
The employment as Postdoc is a full-time position for 2 years. Starting date is 15 November 2023, or after agreement.

Salary, pension and other conditions of employment are set in accordance with the Agreement between the Ministry of Taxation and AC (Danish Confederation of Professional Associations) or other relevant organisation. Currently, the monthly salary starts at 36,290 DKK/ approx. 4,870 EUR (April 2023 level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.

Non-Danish and Danish applicants may be eligible for tax reductions if they hold a PhD degree and have not lived in Denmark for the last 10 years.

The position is covered by the Job Structure for Academic Staff at Universities 2020.

Questions

For further information about the position, please contact Associate Professor Christoffer Clemmensen ([email protected]). For questions regarding the recruitment procedure, please contact HR at [email protected].

The University of Copenhagen International Staff Mobility office offers support and assistance to all international researchers on all issues related to moving to and settling in Denmark.

Application Procedure
Your online application must be submitted in English via the ‘Apply now’ link below. Furthermore, your application must include the following documents/attachments – all in PDF format:

  • Cover letter expressing the motivation and previous research experience of the applicant (max. one page)
  • Curriculum vitae
  • Copy of the PhD degree certificate and the Master’s degree certificate.
  • List of publications
  • References (name and contact details of at least two references)

Application Deadline: 29 August 2023, 23.59pm CET

We reserve the right not to consider material received after the deadline and not to consider applications that do not live up to the abovementioned requirements.

The Further Process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed, each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at www.employment.ku.dk/faculty/recruitment-process.

The applicant will be assessed according to Ministerial Order No. 242 of March 13, 2012, on the Appointment of Academic Staff at Universities.

The University of Copenhagen wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of their personal backgrounds.

Kilde: Jobnet.dk


Information og data

Denne ledige stilling har jobtypen "Forsker", og befinder sig i kategorien "Sundhed og forskning".

Arbejdsstedet er beliggende i København N.

Jobbet er oprettet på vores service den 16.8.2023, men kan have været deaktiveret og genaktiveret igen.

Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
  • Forsker
  • København N
  • Tirsdag den 29. august 2023

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