Research Assistant Positions in enhancer regulation in pluripotent stem cells at reNEW
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The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW) at Faculty of Health & Medical Sciences at the University of Copenhagen is looking for research assistants to join the Brickman group starting January 1st 2024 or upon agreement with the chosen candidate.
The Center:
The Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW has its Hub at the University of Copenhagen (UCPH) as well as nodes at UCPH, Murdoch Children’s Research Institute and Leiden University Medical Center. Researchers within reNEW addresses fundamental questions in stem cell and developmental biology and will pivot research findings to clinical outcomes and products.
Our research
The Brickman group is interested in the transcriptional basis for cell fate choice, exploring both fundamental mechanisms of transcriptional regulation by signaling and how gene regulatory networks define cell potency and fate in development and differentiation. We focus principally on pluripotent stem cells and their differentiation to various types of endoderm as a model system, both embryonic and extra-embryonic. Our recent work points to new paradigms for how transcription factors regulate enhancer potential and interpret signaling, including the finding that response to MAP kinase (ERK) signaling, plasticity and regeneration in early development is dependent on transcription factor occupancy. This project will explore how enhancers are activated in response to ERK signaling, understanding the molecular basis for enhancer activity by exploiting signaling models and understanding how enhancer status safeguards early developmental potential.
Job description:
We are seeking an enthusiastic and outstanding candidates with a background in human stem cell biology. The candidates will implement cutting-edge genetic and metabolomic assays to unravel how metabolism regulates chromatin states in early human development. This positions commences on January 1st 2024.
Qualifications:
We offer:
Terms of salary, work, and employment:
Salary, pension and other conditions of employment are set in accordance with the Agreement between the Ministry of Taxation and AC (Danish Confederation of Professional Associations) or other relevant organisation. Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.
The position is covered by the Job Structure for Academic Staff at Universities 2020.
We encourage all - regardless of their personal background and status - to apply.
The application must include:
Questions:
For further information contact Professor Jashua Brickman, [email protected]
Applicants may find the following links useful: www.ism.ku.dk (International Staff Mobility) and www.workingconditions.ku.dk.
How to apply
Your online application must be submitted in English, by clicking on “Apply online” below.
The University of Copenhagen wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of personal background.
Only applications received in time and consisting of the above listed documents will be considered.
Applications and/or any material received after deadline will not be taken into consideration.
The application will be assessed according to the Ministerial Order no. 284 of 25 April 2008 on the Appointment of Academic Staff at Universities.
Application deadline 15 October 2023, 23.59pm CET
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
Assessment procedure
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Appointments Committee. All applicants are then immediately notified whether their application has been passed for assessment by an expert assessment committee. Selected applicants are notified of the composition of the committee and each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself. You can read about the recruitment process at http://employment.ku.dk
Founded in 1479, the University of Copenhagen is the oldest university in Denmark. It is among the largest universities in Scandinavia and is one of the highest ranking in Europe. The University´s eight faculties include Health Sciences, Humanities, Law, Life Sciences, Pharmaceutical Sciences, Science, Social Sciences and Theology. www.ku.dk
Kilde: Jobnet.dk
The Center:
The Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW has its Hub at the University of Copenhagen (UCPH) as well as nodes at UCPH, Murdoch Children’s Research Institute and Leiden University Medical Center. Researchers within reNEW addresses fundamental questions in stem cell and developmental biology and will pivot research findings to clinical outcomes and products.
Our research
The Brickman group is interested in the transcriptional basis for cell fate choice, exploring both fundamental mechanisms of transcriptional regulation by signaling and how gene regulatory networks define cell potency and fate in development and differentiation. We focus principally on pluripotent stem cells and their differentiation to various types of endoderm as a model system, both embryonic and extra-embryonic. Our recent work points to new paradigms for how transcription factors regulate enhancer potential and interpret signaling, including the finding that response to MAP kinase (ERK) signaling, plasticity and regeneration in early development is dependent on transcription factor occupancy. This project will explore how enhancers are activated in response to ERK signaling, understanding the molecular basis for enhancer activity by exploiting signaling models and understanding how enhancer status safeguards early developmental potential.
Job description:
We are seeking an enthusiastic and outstanding candidates with a background in human stem cell biology. The candidates will implement cutting-edge genetic and metabolomic assays to unravel how metabolism regulates chromatin states in early human development. This positions commences on January 1st 2024.
Qualifications:
- A MSc degree in life sciences or equivalent
- Documented hands-on experience with human pluripotent stem cells is required.
- Excellent English skills written and spoken
- Highly motivated and ambitious candidates are encouraged to apply. The position requires solid previous laboratory work experience.
- A solution-oriented, organizational, and positive mindset is required. The ability to work in a highly collaborative international environment both independently and as part of the team is essential.
We offer:
- A stimulating, challenging and multifaceted research environment
- A supportive team to work and collaborate with
- A combination of exciting projects and state-of-the-art technologies to expand your horizons
- Possibilities for continued education and training
- Attractive employment conditions one position for 1 year and one position for 1 year and 4 months.
- Centrally located workplace
Terms of salary, work, and employment:
Salary, pension and other conditions of employment are set in accordance with the Agreement between the Ministry of Taxation and AC (Danish Confederation of Professional Associations) or other relevant organisation. Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.
The position is covered by the Job Structure for Academic Staff at Universities 2020.
We encourage all - regardless of their personal background and status - to apply.
The application must include:
- Motivation letter
- Curriculum vitae incl. education, experience, previous employments, language skills and other relevant skills
- List of three references (full address, incl. email and phone number)
- Certified copy of original Master of Science diploma and transcript of records in the original language, including an authorized English translation if issued in other language than English or Danish. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor is accepted. As a prerequisite for a PhD fellowship employment, your master’s degree must be equivalent to a Danish master’s degree. We encourage you to read more in the assessment database: https://ufm.dk/en/education/recognition-and-transparency/find-assessments/assessment-database. Please note that we might ask you to obtain an assessment of your education performed by the Ministry of Higher Education and Science
Questions:
For further information contact Professor Jashua Brickman, [email protected]
Applicants may find the following links useful: www.ism.ku.dk (International Staff Mobility) and www.workingconditions.ku.dk.
How to apply
Your online application must be submitted in English, by clicking on “Apply online” below.
The University of Copenhagen wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of personal background.
Only applications received in time and consisting of the above listed documents will be considered.
Applications and/or any material received after deadline will not be taken into consideration.
The application will be assessed according to the Ministerial Order no. 284 of 25 April 2008 on the Appointment of Academic Staff at Universities.
Application deadline 15 October 2023, 23.59pm CET
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
Assessment procedure
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Appointments Committee. All applicants are then immediately notified whether their application has been passed for assessment by an expert assessment committee. Selected applicants are notified of the composition of the committee and each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself. You can read about the recruitment process at http://employment.ku.dk
Founded in 1479, the University of Copenhagen is the oldest university in Denmark. It is among the largest universities in Scandinavia and is one of the highest ranking in Europe. The University´s eight faculties include Health Sciences, Humanities, Law, Life Sciences, Pharmaceutical Sciences, Science, Social Sciences and Theology. www.ku.dk
Kilde: Jobnet.dk
Information og data
Denne ledige stilling har jobtypen "Forsker", og befinder sig i kategorien "Sundhed og forskning".
Arbejdsstedet er beliggende i København N.
Jobbet er oprettet på vores service den 30.9.2023, men kan have været deaktiveret og genaktiveret igen.
Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
- Forsker
- København N
- Søndag den 15. oktober 2023
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