Research Assistant in Cell, Tissue and DNA Handling and Sequencing at Supek lab, BRIC

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København N

Faculty of Health and Medical Sciences
University of Copenhagen


At BRIC a position as Research Assistant is vacant from 1 February 2024, or after agreement.

Job description
We are looking for an enthusiastic research assistant to join the team of the ERC project “STRUCTOMATIC” and play an important role in obtaining material and preparing DNA/RNA from cancer cell lines and tumor tissues, and performing DNA/RNA sequencing at a medium scale (100s of biological samples).

This will be accomplished by liaising with external collaborators, acquiring samples of cells/tissues from collaborators, processing them to extract DNA/RNA, performing quality-control and library prep on the DNA/RNA, and sequencing it on an Oxford Nanopore long-read sequencer. Generated genomic (or mRNA) data needs to be organized in a catalog, where it will form a central resource for the lab’s research in cancer genome evolution. Finally, the research assistant will also support other team members in tasks related with cell culture of cancer cell lines.

Information on the department can be found at: https://www.bric.ku.dk/.

Our research
The Supek group is home to a highly interdisciplinary team, working at the intersection of genomics, molecular biology, and artificial intelligence. In our studies, we are striving for excellence and impact – we aim to do science that pushes the boundaries of knowledge, and that benefits human health and development. The lab employs cutting-edge technologies in DNA/RNA sequencing (e.g. Nanopore data generation and analysis), gene editing (e.g. Cas12a combinatorial disruption) and artificial intelligence (e.g. DNA and protein language models).

In addition to focus on high-impact research projects (ERC “HYPER-INSIGHT”, ERC “STRUCTOMATIC”), the Supek group also has a broad network of international collaborators across Europe (see e.g. EU Horizon consortia “DECIDER” and “LUCIA”, where we study ovarian and lung cancer genomes, respectively). The lab fosters a dynamic atmosphere where excitement about science is valued. We are highly committed to mentoring and career development of all our members.

Profile
Applicants must have qualifications corresponding to a master’s degree related to the subject area of the project. Please note that your master’s degree must be equivalent to a Danish master’s degree (two years).
We are looking for a highly motivated and enthusiastic colleague with the following competencies and experience:

  • You have a degree at Master level.
  • You are experienced in laboratory techniques dealing with manipulation of tissues and cells, DNA/RNA extraction and quality-control, and mammalian cell culture.
  • You have an active interest in taking part in an exciting, collaborative scientific project, communicating with external collaborators and coordinating collaboration activities (e.g. obtaining cells/tissue samples).
  • You have an active interest in using cutting-edge sequencing techniques (Nanopore long read sequencing).
  • Proficient communication skills and ability to work in teams
  • Very good English skills, written and spoken

Desirable experience and skills:

  • Experience in laboratory techniques dealing with handling of mammalian tissues, mammalian cell culture (passaging, viability assays, expansion of clones), and DNA/RNA extraction and quality-control.
  • Experience in laboratory techniques for recombinant DNA, including library prep for sequencing, PCR or cloning.
  • Experience with administration/coordination of larger research projects involving multiple external collaborators, including liaising with collaborators.
  • Experience with organizing acquisition/shipping/storing/cataloguing of material (reagents, cells, tissues, DNAs) from external sources.
  • Optionally, experience with use of genomics databases (e.g. SRA, dbGaP, EGA, GEO…) and work with DNA/RNA sequence data is a plus but not mandatory.

Place of employment
The place of employment is at BRIC, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and high-performance computing infrastructure.

Terms of employment
The average weekly working hours are 37 hours per week.

The position is a fixed-term position limited to a period of 3 years and is to commence 1 February 2024 or as soon as possible hereafter.

Salary, pension, and other conditions of employment are set in accordance with the Agreement between the Ministry of Taxation and AC (Danish Confederation of Professional Associations) or another relevant organisation.

Currently, the monthly salary starts at 31,147 DKK/approx. 4,175 EUR (October 2023 level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.

The position is covered by the Job Structure for Academic Staff at Universities 2020.

Questions
For further information about the project please contact Prof. Fran Supek, [email protected].

Foreign applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).

Application procedure
Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:

  1. Motivated letter of application (max. one page).
  2. CV incl. education, work/research experience, language skills and other skills relevant for the position.
  3. Certified copy of original Master of Science diploma and transcript of records in the original language, including an authorized English translation if issued in other language than English or Danish. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor is accepted. As a prerequisite for a PhD fellowship employment, your master’s degree must be equivalent to a Danish master’s degree. We encourage you to read more in the assessment database: https://ufm.dk/en/education/recognition-and-transparency/find-assessments/assessment-database. Please note that we might ask you to obtain an assessment of your education performed by the Ministry of Higher Education and Science
  4. Scientific qualifications (optional). You may attach up to 5 publications or preprints or conference abstracts.

Deadline for applications: 20 November 2023, 23.59pm CET

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/.

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

Interviews are expected to be held during December 2023.

The University of Copenhagen wish to reflect the diversity of society and encourage all qualified candidates to apply regardless of personal background.

Kilde: Jobnet.dk


Information og data

Denne ledige stilling har jobtypen "Forsker", og befinder sig i kategorien "Sundhed og forskning".

Arbejdsstedet er beliggende i København N.

Jobbet er oprettet på vores service den 21.10.2023, men kan have været deaktiveret og genaktiveret igen.

Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
  • Forsker
  • København N
  • Mandag den 20. november 2023

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