Postdoc in mechanistic and physiological investigation of energy sensing enzyme AMPK
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København N
Novo Nordisk Foundation Center for Basic Metabolic Research
University of Copenhagen
The University of Copenhagen is seeking an experienced Postdoc fellow to commence on April 1, 2024, or after agreement, for the Sakamoto Group at the Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR), University of Copenhagen.
About Us
The Novo Nordisk Foundation Center for Basic Metabolic Research’s vision is to pioneer groundbreaking research towards better cardiometabolic health. We wish to lead collaborative interdisciplinary research from single-cell genomics to whole-body systems, transforming the basic understanding of cardiometabolic health, and accelerating its translation into prevention and treatment strategies. We were established in 2010, and in 2017, we moved into new laboratories, offices, and meeting rooms in the Maersk Tower www.maersktower.ku.dk.
The Center has around 260 employees who work in an international, highly collaborative research environment across a range of biomedical disciplines. You can read more about us here: www.cbmr.ku.dk.
Our Research
The Sakamoto Group investigates fundamental molecular signaling mechanisms that control energy homeostasis and elucidates the regulation/function of potential therapeutic targets related to cardiometabolic disease. We take a multidisciplinary approach, have access to cutting-edge technologies/facilities, collaborate with renowned national/international experts, and support development of early career researchers.
Job Description
AMP-activated protein kinase (AMPK) is a master regulator of cellular energy homeostasis and a therapeutic target for cardiometabolic diseases. This project aims to uncover molecular mechanism(s) by which AMPK regulatory subunit myristoylation and carbohydrate-binding module regulates specific metabolic functions through controlling cellular localization and protein-protein or protein-metabolite interactions. The project will be driven by the successful candidate via multifaceted approaches, including structure-guided mutagenesis, gene-editing, enzyme kinetics (in vitro), proteomics, cell imaging, in vivo metabolic analyses and through international collaborations with renowned research groups.
Profile
We are looking for a highly motivated and enthusiastic scientist with the following competencies and experience:
Required qualifications:
Terms of Employment
The employment as Postdoc is a full-time position for 3 years. Starting date is April 1, 2024, or after agreement.
Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Depending on qualifications, a supplement may be negotiated.
Non-Danish and Danish applicants may be eligible for tax reductions if they hold a PhD degree and have not lived in Denmark for the past 10 years.
The position is covered by the Job Structure for Academic Staff at Universities 2020.
Questions
For further information about the position, please contact Professor Kei Sakamoto at [email protected]. For questions regarding the recruitment procedure, please contact HR at [email protected].
The University of Copenhagen International Staff Mobility office offers support and assistance to all international researchers on all issues related to moving to and settling in Denmark.
Application Procedure
Your online application must be submitted in English via the ‘Apply now’ link below. Furthermore, your application must include the following documents/attachments – all in PDF format:
Application Deadline: January 21, 2024, 23.59pm CET.
We reserve the right not to consider material received after the deadline and not to consider applications that do not live up to the abovementioned requirements.
The Further Process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed, each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.
You can read about the recruitment process at www.employment.ku.dk/faculty/recruitment-process.
The applicant will be assessed according to Ministerial Order No. 242 of March 13, 2012, on the Appointment of Academic Staff at Universities.
The University of Copenhagen wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of their personal backgrounds.
Kilde: Jobnet.dk
University of Copenhagen
The University of Copenhagen is seeking an experienced Postdoc fellow to commence on April 1, 2024, or after agreement, for the Sakamoto Group at the Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR), University of Copenhagen.
About Us
The Novo Nordisk Foundation Center for Basic Metabolic Research’s vision is to pioneer groundbreaking research towards better cardiometabolic health. We wish to lead collaborative interdisciplinary research from single-cell genomics to whole-body systems, transforming the basic understanding of cardiometabolic health, and accelerating its translation into prevention and treatment strategies. We were established in 2010, and in 2017, we moved into new laboratories, offices, and meeting rooms in the Maersk Tower www.maersktower.ku.dk.
The Center has around 260 employees who work in an international, highly collaborative research environment across a range of biomedical disciplines. You can read more about us here: www.cbmr.ku.dk.
Our Research
The Sakamoto Group investigates fundamental molecular signaling mechanisms that control energy homeostasis and elucidates the regulation/function of potential therapeutic targets related to cardiometabolic disease. We take a multidisciplinary approach, have access to cutting-edge technologies/facilities, collaborate with renowned national/international experts, and support development of early career researchers.
Job Description
AMP-activated protein kinase (AMPK) is a master regulator of cellular energy homeostasis and a therapeutic target for cardiometabolic diseases. This project aims to uncover molecular mechanism(s) by which AMPK regulatory subunit myristoylation and carbohydrate-binding module regulates specific metabolic functions through controlling cellular localization and protein-protein or protein-metabolite interactions. The project will be driven by the successful candidate via multifaceted approaches, including structure-guided mutagenesis, gene-editing, enzyme kinetics (in vitro), proteomics, cell imaging, in vivo metabolic analyses and through international collaborations with renowned research groups.
Profile
We are looking for a highly motivated and enthusiastic scientist with the following competencies and experience:
Required qualifications:
- PhD in biochemistry, molecular biomedicine, cell biology, nutrition, or related sciences
- Excellent scientific track record (i.e., publications, training) in relation to career stage
- Profound knowledge on biochemistry and cellular signaling in relation to energy metabolism
- Profound experimental skills in biochemistry (e.g., enzymology) and cell biology (e.g., imaging)
- Basic knowledge on metabolic diseases, including obesity, insulin resistance and type 2 diabetes
- Having a FELASA or equivalent certification for animal experimentation is desirable.
- A curious and innovative mindset with strong self-motivation to develop new knowledge and treatment for complex cardiometabolic diseases
- Excellent English communication skills, both written and oral
Terms of Employment
The employment as Postdoc is a full-time position for 3 years. Starting date is April 1, 2024, or after agreement.
Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Depending on qualifications, a supplement may be negotiated.
Non-Danish and Danish applicants may be eligible for tax reductions if they hold a PhD degree and have not lived in Denmark for the past 10 years.
The position is covered by the Job Structure for Academic Staff at Universities 2020.
Questions
For further information about the position, please contact Professor Kei Sakamoto at [email protected]. For questions regarding the recruitment procedure, please contact HR at [email protected].
The University of Copenhagen International Staff Mobility office offers support and assistance to all international researchers on all issues related to moving to and settling in Denmark.
Application Procedure
Your online application must be submitted in English via the ‘Apply now’ link below. Furthermore, your application must include the following documents/attachments – all in PDF format:
- Cover letter expressing the motivation and previous research experience of the applicant (max. one page)
- Curriculum vitae
- Copy of the PhD degree certificate and the Master’s degree certificate.
- List of publications
- References (name and contact details of at least two references)
Application Deadline: January 21, 2024, 23.59pm CET.
We reserve the right not to consider material received after the deadline and not to consider applications that do not live up to the abovementioned requirements.
The Further Process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed, each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.
You can read about the recruitment process at www.employment.ku.dk/faculty/recruitment-process.
The applicant will be assessed according to Ministerial Order No. 242 of March 13, 2012, on the Appointment of Academic Staff at Universities.
The University of Copenhagen wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of their personal backgrounds.
Kilde: Jobnet.dk
Information og data
Denne ledige stilling har jobtypen "Forsker", og befinder sig i kategorien "Sundhed og forskning".
Arbejdsstedet er beliggende i København N.
Jobbet er oprettet på vores service den 8.1.2024, men kan have været deaktiveret og genaktiveret igen.
Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
- Forsker
- København N
- Søndag den 21. januar 2024
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