Senior/Principal Laboratory Technician - Protein Purification and Characterization
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Ballerup
Dragonfly Therapeutics is looking for a senior/principal technician with a passion for protein purification and characterization to join our dedicated Biologics team in Copenhagen, Denmark.
The successful candidate will be a key member of Dragonfly’s talented and collaborative team, contributing to the discovery and development of novel immunotherapies for treatment of cancer and chronic inflammatory diseases.
The successful candidate will perform studies and develop innovative methods for purification and biophysical/chemical characterization of a wide variety of mono-, bi- and tri-specific antibody formats and be a central player in providing data on discovery candidates for lead selection. Dragonfly Therapeutics is an exciting young company that offers a fantastic culture and great opportunities to enhance your skills and grow your career.
Responsibilities
Qualifications
We offer
Our employees are fundamental to our success, and we continue to be able to attract and retain people with different experiences and backgrounds. We have a high-performing, collaborative culture characterized by respectful and diverse teams who are committed to our patients first mission. At Dragonfly, you will have the opportunity to have impact, work with some of the brightest minds in the industry, develop your professional career, and contribute to breakthrough medicines for patients with urgent unmet medical needs.
About Dragonfly
Founded in 2015 by Dr. Tyler Jacks, head of the Koch Institute at MIT, Dr. David Raulet, one of the world's leading experts in Natural Killer (NK) cell biology, and Bill Haney, a longtime tech entrepreneur and investor, Dragonfly Therapeutics was launched to harness the power of the immune system to provide breakthrough treatments for patients – especially in areas where there are no effective treatments, today.
The company develops novel first-in-class therapeutics designed to harness Natural Killer cells and other cells of the innate immune system, which can provide direct killing of disease promoting cell types and provide a unique therapeutic window beyond current therapies for treatment of cancer and chronic inflammatory diseases.
Our mission is to revolutionize disease treatment by inventing natural killer cell-based therapies for vastly improved patient outcomes. We believe in a small team with a big impact.
Please visit our website for details.
Your application
Please apply by sending a cover letter and resume as soon as possible through the button "Apply / Send ansøgning". We are screening and interviewing for the position on an ongoing basis. For any further questions please email [email protected].
For more info, check out our career site https://dragonflytx.ofir.com
Denne jobannonce blev oprindeligt opslået på https://www.ofir.dk/
(Den originale annonce kan ses på: https://www.ofir.dk/showojob?ofirid=d90bc206)
Kilde: Jobnet.dk
The successful candidate will be a key member of Dragonfly’s talented and collaborative team, contributing to the discovery and development of novel immunotherapies for treatment of cancer and chronic inflammatory diseases.
The successful candidate will perform studies and develop innovative methods for purification and biophysical/chemical characterization of a wide variety of mono-, bi- and tri-specific antibody formats and be a central player in providing data on discovery candidates for lead selection. Dragonfly Therapeutics is an exciting young company that offers a fantastic culture and great opportunities to enhance your skills and grow your career.
Responsibilities
- Purification and optimization of downstream processing of antibodies, to support candidate profiling and guide lead selection for Dragonfly's discovery projects.
- Provide biophysical and biochemical characterization data to support selection of antibody candidates with superior developability profiles and a clear path towards CMC development.
- Collaborate with the global Biologics team and cross functional project groups to support production and characterization of antibody candidates for successful progression of our discovery projects.
- Implement technologies for kinetic analysis of protein-protein interactions, e.g. SPR, in the DK Biologics team.
- Explore and implement new technologies to improve Dragonfly’s antibody purification and characterization capabilities.
- Analyze data, interpret and communicate results including providing input to technical reports and internal/external project presentations.
- Ensure timely, high-quality and appropriate documentation in electronic laboratory notebooks.
Qualifications
- An educational background as Laboratory Technician within the field of protein biochemistry, analytical chemistry or related disciplines.
- 5+ years of experience from industry, preferably within biotherapeutic drug discovery.
- Strong hands-on experience with protein purification, using different affinity-, IEX-, HIC- or SEC-based chromatographic methods.
- Extensive practical knowledge on purification of antibodies and Fc-fusion proteins using ÄKTA pure, ÄKTA avant or similar chromatography systems.
- Expertise in protein biochemistry and analytical characterization using chromatographic, electrophoretic and other methods, such as HPLC-based assays, DSF, DLS, cIEF and CE-SDS for protein characterization.
- Experience with protein-protein interaction analyses by SPR, ELISA, MST or other methods is highly desirable.
- Highly motivated with a quality and detail-oriented mind-set and able to work in a fast-paced team environment.
- Team player with the ability to work collaboratively, provide input and communicate clearly both written and orally in English.
- Excellent record keeping abilities to document analytical data.
We offer
Our employees are fundamental to our success, and we continue to be able to attract and retain people with different experiences and backgrounds. We have a high-performing, collaborative culture characterized by respectful and diverse teams who are committed to our patients first mission. At Dragonfly, you will have the opportunity to have impact, work with some of the brightest minds in the industry, develop your professional career, and contribute to breakthrough medicines for patients with urgent unmet medical needs.
About Dragonfly
Founded in 2015 by Dr. Tyler Jacks, head of the Koch Institute at MIT, Dr. David Raulet, one of the world's leading experts in Natural Killer (NK) cell biology, and Bill Haney, a longtime tech entrepreneur and investor, Dragonfly Therapeutics was launched to harness the power of the immune system to provide breakthrough treatments for patients – especially in areas where there are no effective treatments, today.
The company develops novel first-in-class therapeutics designed to harness Natural Killer cells and other cells of the innate immune system, which can provide direct killing of disease promoting cell types and provide a unique therapeutic window beyond current therapies for treatment of cancer and chronic inflammatory diseases.
Our mission is to revolutionize disease treatment by inventing natural killer cell-based therapies for vastly improved patient outcomes. We believe in a small team with a big impact.
Please visit our website for details.
Your application
Please apply by sending a cover letter and resume as soon as possible through the button "Apply / Send ansøgning". We are screening and interviewing for the position on an ongoing basis. For any further questions please email [email protected].
For more info, check out our career site https://dragonflytx.ofir.com
Denne jobannonce blev oprindeligt opslået på https://www.ofir.dk/
(Den originale annonce kan ses på: https://www.ofir.dk/showojob?ofirid=d90bc206)
Kilde: Jobnet.dk
Information og data
Denne ledige stilling har jobtypen "Laborant", og befinder sig i kategorien "Sundhed og forskning".
Arbejdsstedet er beliggende i Ballerup.
Jobbet er oprettet på vores service den 11.10.2021, men kan have været deaktiveret og genaktiveret igen.
Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
- Laborant
- Ballerup
- Mandag den 15. november 2021
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