PhD fellowship in Biochemistry
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PhD Project in transcription factor biophysics
Department of Biology
Faculty of SCIENCE
University of Copenhagen
The Heidarsson group at the Section for Biomolecular Sciences invites applicants for a PhD fellowship in Intrinsically disordered transcription factors and their interactions with chromatin. The project is part of the research project “PIONEER”, which is financed by an ERC Starting Grant.
Start date is expected to be 1. September or as soon as possible thereafter.
The project
The successful candidate will join the research group led by Dr. Pétur O. Heiðarsson, [email protected], working on understanding the interactions of pioneer transcription factors with chromatin and their link to cell reprogramming mechanisms. Key pluripotency transcription factors will be fluorescently labelled for single-molecule FRET experiments in vitro and used to construct molecular models of their complexes with reconstituted nucleosomes. NMR spectroscopy and various other biophysical methods will be used to complement the single-molecule studies.
Who are we looking for?
We are looking for candidates within the field(s) of biochemistry or biophysics. Applicants can have a background from biophysics, using methods such as NMR spectroscopy and single-molecule spectroscopy, and have a solid grasp of programming such as using Mathematica or Python.
Our group and research- and what do we offer?
The Heiðarsson group is a part of the Department of Biology, Faculty of SCIENCE, University of Copenhagen. We are located in Copenhagen. The group uses cutting-edge single-molecule spectroscopy and microscopy as a core technique to investigate transcription factors operating on a dynamic nucleoprotein landscape, specifically focusing on the role of intrinsically disordered regions.
We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and state-of-the-art facilities for recombinant protein production as well as analytical tools such as NMR, CD, ITC, MST, and Q-TOF MS for biophysical and biochemical characterization. Our group is part of the Novo Nordisk Foundation Challenge Center REPIN, which is a consortium of 5 different research groups.
Principal supervisor isAssociate professor Pétur Heiðarsson, Department of Biology, [email protected].
The PhD programme
A three year full-time study within the framework of the regular PhD programme (5+3 scheme), if you already have an education equivalent to a relevant Danish master’s degree.
Qualifications needed
To be eligible for the PhD programme, you must have completed a degree programme, equivalent to a Danish master’s degree (180 ECTS/3 FTE BSc + 120 ECTS/2 FTE MSc) related to the subject area of the project, e.g. For information of eligibility of completed programmes, see General assessments for specific countries and Assessment database.
Terms of employment in the regular programme
Employment as PhD fellow is full time and for maximum 3 years.
Employment is conditional upon your successful enrolment as a PhD student at the PhD School at the Faculty of SCIENCE, University of Copenhagen. This requires submission and acceptance of an application for the specific project formulated by the applicant.
Terms of appointment and payment accord to the agreement between the Danish Ministry of Taxation and The Danish Confederation of Professional Associations on Academics in the State. The position is covered by the Protocol on Job Structure.
Responsibilities and tasks the PhD programme
We are looking for the following qualifications:
***************************************************************************
Application and Assessment Procedure
Your application including all attachments must be in English and submitted electronically by clicking APPLY NOW below.
Please include:
Application deadline:
The deadline for applications is 9 June 2024, 23:59 GMT +2
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
The further process
After deadline, a number of applicants will be selected for academic assessment by an unbiased expert assessor. You are notified, whether you will be passed for assessment.
The assessor will assess the qualifications and experience of the shortlisted applicants with respect to the above mentioned research area, techniques, skills and other requirements. The assessor will conclude whether each applicant is qualified and, if so, for which of the two models. The assessed applicants will have the opportunity to comment on their assessment. You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/.
Questions
For specific information about the PhD fellowship, please contact the principal supervisor.
General information about PhD study at the Faculty of SCIENCE is available at the PhD School’s website: https://www.science.ku.dk/phd/.
The University of Copenhagen wishes to reflect the surrounding community and invites all regardless of personal background to apply for the position.
Kilde: Jobnet.dk
Department of Biology
Faculty of SCIENCE
University of Copenhagen
The Heidarsson group at the Section for Biomolecular Sciences invites applicants for a PhD fellowship in Intrinsically disordered transcription factors and their interactions with chromatin. The project is part of the research project “PIONEER”, which is financed by an ERC Starting Grant.
Start date is expected to be 1. September or as soon as possible thereafter.
The project
The successful candidate will join the research group led by Dr. Pétur O. Heiðarsson, [email protected], working on understanding the interactions of pioneer transcription factors with chromatin and their link to cell reprogramming mechanisms. Key pluripotency transcription factors will be fluorescently labelled for single-molecule FRET experiments in vitro and used to construct molecular models of their complexes with reconstituted nucleosomes. NMR spectroscopy and various other biophysical methods will be used to complement the single-molecule studies.
Who are we looking for?
We are looking for candidates within the field(s) of biochemistry or biophysics. Applicants can have a background from biophysics, using methods such as NMR spectroscopy and single-molecule spectroscopy, and have a solid grasp of programming such as using Mathematica or Python.
Our group and research- and what do we offer?
The Heiðarsson group is a part of the Department of Biology, Faculty of SCIENCE, University of Copenhagen. We are located in Copenhagen. The group uses cutting-edge single-molecule spectroscopy and microscopy as a core technique to investigate transcription factors operating on a dynamic nucleoprotein landscape, specifically focusing on the role of intrinsically disordered regions.
We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and state-of-the-art facilities for recombinant protein production as well as analytical tools such as NMR, CD, ITC, MST, and Q-TOF MS for biophysical and biochemical characterization. Our group is part of the Novo Nordisk Foundation Challenge Center REPIN, which is a consortium of 5 different research groups.
Principal supervisor isAssociate professor Pétur Heiðarsson, Department of Biology, [email protected].
The PhD programme
A three year full-time study within the framework of the regular PhD programme (5+3 scheme), if you already have an education equivalent to a relevant Danish master’s degree.
Qualifications needed
To be eligible for the PhD programme, you must have completed a degree programme, equivalent to a Danish master’s degree (180 ECTS/3 FTE BSc + 120 ECTS/2 FTE MSc) related to the subject area of the project, e.g. For information of eligibility of completed programmes, see General assessments for specific countries and Assessment database.
Terms of employment in the regular programme
Employment as PhD fellow is full time and for maximum 3 years.
Employment is conditional upon your successful enrolment as a PhD student at the PhD School at the Faculty of SCIENCE, University of Copenhagen. This requires submission and acceptance of an application for the specific project formulated by the applicant.
Terms of appointment and payment accord to the agreement between the Danish Ministry of Taxation and The Danish Confederation of Professional Associations on Academics in the State. The position is covered by the Protocol on Job Structure.
Responsibilities and tasks the PhD programme
- Carry through an independent research project under supervision
- Complete PhD courses corresponding to approx. 30 ECTS / ½ FTE
- Participate in active research environments, including a stay at another research institution, preferably abroad
- Teaching and knowledge dissemination activities
- Write scientific papers aimed at high-impact journals
- Write and defend a PhD thesis on the basis of your project
We are looking for the following qualifications:
- Professional qualifications relevant to the PhD project
- Relevant publications
- Relevant work experience
- Other relevant professional activities
- Curious mind-set with a strong interest in intrinsically disordered transcription factors
- Good language skills
***************************************************************************
Application and Assessment Procedure
Your application including all attachments must be in English and submitted electronically by clicking APPLY NOW below.
Please include:
- Motivated letter of application (max. one page)
- Your motivation for applying for the specific PhD project
- Curriculum vitae including information about your education, experience, language skills and other skills relevant for the position
- Original diplomas for Bachelor of Science or Master of Science and transcript of records in the original language, including an authorized English translation if issued in another language than English or Danish. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor is accepted.
- Publication list (if possible)
- Reference letters (if available)
Application deadline:
The deadline for applications is 9 June 2024, 23:59 GMT +2
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
The further process
After deadline, a number of applicants will be selected for academic assessment by an unbiased expert assessor. You are notified, whether you will be passed for assessment.
The assessor will assess the qualifications and experience of the shortlisted applicants with respect to the above mentioned research area, techniques, skills and other requirements. The assessor will conclude whether each applicant is qualified and, if so, for which of the two models. The assessed applicants will have the opportunity to comment on their assessment. You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/.
Questions
For specific information about the PhD fellowship, please contact the principal supervisor.
General information about PhD study at the Faculty of SCIENCE is available at the PhD School’s website: https://www.science.ku.dk/phd/.
The University of Copenhagen wishes to reflect the surrounding community and invites all regardless of personal background to apply for the position.
Kilde: Jobnet.dk
Information og data
Denne ledige stilling har jobtypen "Øvrige", og befinder sig i kategorien "Øvrige stillinger".
Arbejdsstedet er beliggende i København Ø.
Jobbet er oprettet på vores service den 24.5.2024, men kan have været deaktiveret og genaktiveret igen.
Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
- Øvrige
- København Ø
- Søndag den 09. juni 2024
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