AC-TAP in the transcriptional regulation of totipotentency at DanStem - København
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We are looking for a highly motivated and independent AC-TAPto support our efforts in understanding how lineage specific transcription factor codes can support totipotent stem cell populations to commence May 2020.
Our research/the project
Embryonic Stem Cells (ESCs) are genetically normal, immortal cell lines with the capacity to become any cell type in the future organism. However canonically they are not able to make the extra-embryonic cell types required for mammalian development. We identified different culture conditions capable of supporting cells with the capacity for differentiation to both embryonic and extra-embryonic lineages, so called totipotent cells. This position will support our efforts to identify and characterize these conditions, the transcription factor and cell growth requirements for these cells and their developmental potential in vivo and in vitro.
Your job
We are looking for a candidate with a strong background in ESC biology, culture and experience with mouse embryology. The candidate is expected to characterize different cell culture models for totipotency. You will also assess their behavior in vivo through the generation of chimeric mice. You will be expected to contribute to and support the ongoing research projects in the group on an ad hoc basis when needed; disseminate your expertise to new lab members and support the lab management.
Profile
The candidate is required to hold an MSc degree in molecular biology/developmental biology/stem cell biology. A candidate should also have hands on experience with ESCs, analysis of ESC chimeras/mouse embryos, as well as practical knowledge general molecular biology techniques.
Place of employment
The Novo Nordisk Foundation Center for Stem Cell Biology – DanStem has been established as a result of a series of international recruitments coupled with internationally recognized research groups focused on insulin producing beta cells and cancer research already located at the University of Copenhagen. DanStem addresses basic research questions in stem cell and developmental biology and has activities focused on the translation of promising basic research results into new strategies and targets for the development of new therapies for cancer and chronic diseases such as diabetes and liver failure. Find more information about the Center at http://danstem.ku.dk/.
Terms of salary and employment
The employment as (AC-TAP) is a full time and fixed-term position for 3 years. Starting date is March 2020 or after agreement. Employment will be in accordance with the provisions of the collective agreement between the Danish Ministry of Finance and AC (the Danish Confederation of Professional Associations). The monthly salary will be based on the number of years of work experience (seniority) with the possibility to negotiate a salary supplement based on prior experiences and qualifications. The employer will pay an additional 17.1 % to your pension fund.
Questions
For further information regarding the position, please contact Josh Brickman, [email protected]
Application
Your application should be in English and must include:
Please submit your application by clicking on “Apply Now” below. Only online applications will be accepted.
Application deadline: 16 March 2020, 23.59 CET
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates regardless of age, disability, gender, nationality, race, religion or sexual orientation. Appointment will be based on merit alone.
Kilde: Jobnet.dk
Our research/the project
Embryonic Stem Cells (ESCs) are genetically normal, immortal cell lines with the capacity to become any cell type in the future organism. However canonically they are not able to make the extra-embryonic cell types required for mammalian development. We identified different culture conditions capable of supporting cells with the capacity for differentiation to both embryonic and extra-embryonic lineages, so called totipotent cells. This position will support our efforts to identify and characterize these conditions, the transcription factor and cell growth requirements for these cells and their developmental potential in vivo and in vitro.
Your job
We are looking for a candidate with a strong background in ESC biology, culture and experience with mouse embryology. The candidate is expected to characterize different cell culture models for totipotency. You will also assess their behavior in vivo through the generation of chimeric mice. You will be expected to contribute to and support the ongoing research projects in the group on an ad hoc basis when needed; disseminate your expertise to new lab members and support the lab management.
Profile
The candidate is required to hold an MSc degree in molecular biology/developmental biology/stem cell biology. A candidate should also have hands on experience with ESCs, analysis of ESC chimeras/mouse embryos, as well as practical knowledge general molecular biology techniques.
Place of employment
The Novo Nordisk Foundation Center for Stem Cell Biology – DanStem has been established as a result of a series of international recruitments coupled with internationally recognized research groups focused on insulin producing beta cells and cancer research already located at the University of Copenhagen. DanStem addresses basic research questions in stem cell and developmental biology and has activities focused on the translation of promising basic research results into new strategies and targets for the development of new therapies for cancer and chronic diseases such as diabetes and liver failure. Find more information about the Center at http://danstem.ku.dk/.
Terms of salary and employment
The employment as (AC-TAP) is a full time and fixed-term position for 3 years. Starting date is March 2020 or after agreement. Employment will be in accordance with the provisions of the collective agreement between the Danish Ministry of Finance and AC (the Danish Confederation of Professional Associations). The monthly salary will be based on the number of years of work experience (seniority) with the possibility to negotiate a salary supplement based on prior experiences and qualifications. The employer will pay an additional 17.1 % to your pension fund.
Questions
For further information regarding the position, please contact Josh Brickman, [email protected]
Application
Your application should be in English and must include:
- Letter of application addressing the requirements (max. one page).
- Curriculum Vitae
- A certified/signed copy of certificate(s) of education
Please submit your application by clicking on “Apply Now” below. Only online applications will be accepted.
Application deadline: 16 March 2020, 23.59 CET
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates regardless of age, disability, gender, nationality, race, religion or sexual orientation. Appointment will be based on merit alone.
Kilde: Jobnet.dk
Information og data
Denne ledige stilling har jobtypen "Akademisk medarbejder", og befinder sig i kategorien "Økonomi og jura".
Arbejdsstedet er beliggende i København Ø.
Jobbet er oprettet på vores service den 3.3.2020, men kan have været deaktiveret og genaktiveret igen.
Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
- Akademisk medarbejder
- København Ø
- Mandag den 16. marts 2020
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