Two PhD positions in the protein analysis group
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DEPARTMENT OF PHARMACY, FACULTY OF HEALTH AND MEDICAL SCIENCES, UNIVERSITY OF COPENHAGEN
The Department of Pharmacy, under the Faculty of Health and Medical Sciences, University of Copenhagen, invites applications for two PhD positions, for a period of 3 years, starting from 1st Oct, Nov or Dec 2021.
Job description
Proteins are versatile and highly potent drug candidates and account for a rapidly growing number of new drugs in development. Specialized analytical tools are needed to characterize these large and complex biomolecules. Hydrogen/deuterium exchange mass spectrometry (HDX-MS) has become an established analytical technique that can provide unique insights into the conformation, dynamics and interactions of proteins in solution. In a collaboration between the Protein Analysis Group and the Microscale Analytical Systems Group, we will develop microfluidic solutions to improve the HDX-MS method.
The overall aim of both PhD projects is to build on existing work in the group and develop and apply microfluidic components and couple these to mass spectrometry to realize an improved workflow for HDX-MS. The developed microfluidic HDX-MS solutions will be used to investigate several complex protein systems of therapeutic interest.
The two PhD candidates will work in the Protein Analysis Group under the supervision of Professor MSO Kasper Rand (primary supervisor), in close collaboration with the Microscale Analytical Systems Group (co-supervisors Prof. Jorg Kutter or Associate Professor Nickolaj Petersen). The two PhD fellowships are funded through a grant from the European Research Councils (ERC Consolidator Grant).
The key tasks as a PhD student are:
Qualifications required
Applicants must have must have qualifications corresponding to a master’s degree within either of the following fields: microfluidics, analytical chemistry, protein mass spectrometry or HDX-MS. Applicants with lab-based experience within one or more of these areas will be preferred, particularly relevant is the field of microfluidics. The most successful applications will be those with experience with working at the interface between the fields of microfluidics, analytical chemistry and/or protein mass spectrometry/HDX-MS. Finally, the PhD candidates will be expected to engage in some teaching in analytical chemistry at either bachelor or master level courses.
Other important criteria are:
Further information
For further information, please contact either Professor MSO Kasper D. Rand ([email protected], tel. +45 2371 2556).
Place of employment
The Department of Pharmacy plays a key role in advancing the pharmaceutical sciences in Denmark and internationally. It is devoted to research and research-based teaching in drug formulation and manufacturing, drug-related analytical and physical chemistry, drug metabolism, chemical toxicolog and medicines use. The scientific and teaching objectives of the Department encompass the areas of Pharmaceutical Analytical Chemistry, Biopharmaceuticals/Biologics, Pharmaceutical Technology and Engineering; Pharmaceutical Design and Drug Delivery and Clinical and Social Pharmacy.
Terms of employment
The employment as PhD fellow is full time and for 3 years.
It is conditioned upon the applicant’s successful enrolment as a PhD student at the Graduate School at the Faculty of Health and Medical Sciences, University of Copenhagen. This requires submission and acceptance of an application for the specific project formulated by the applicant
The PhD study must be completed in accordance with The Ministerial Order on the PhD programme (2013) and the Faculty’s rules on achieving the degree. Salary, pension and terms of employment are in accordance with the agreement between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State. Depending on seniority, the monthly salary begins around 27.780 DKK /approx. 3.730 EUR (April 2021-level) plus pension.
As an equal opportunities, employer, the University of Copenhagen encourages all qualified applicants to apply, regardless of gender, age, religion and ethnic origin.
Application procedure
Your application must be submitted electronically by clicking ‘Apply now’ below. The application must include the following documents in PDF format:
1. Motivated letter of application (max. one page)
2. CV incl. education, experience, language skills and other skills relevant for the position
3. Master of Science diploma and transcript of records. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor will do
4. Publication list (if possible)
Application deadline: 12 July 2021, 23.59pm CET
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor.
The assessor makes a non-prioritized assessment of the academic qualifications and experience with respect to the above-mentioned area of research, techniques, skills and other requirements listed in the advertisement.
Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.
You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/
The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.
The Faculty of Health and Medical Sciences comprises approximately 7500 students, 1500 PhD students and 3200 employees. The Faculty advances the field of health sciences through its core activities: research, teaching, knowledge sharing and communication. With basic research fields ranging from molecular studies to studies of society, the Faculty contributes to a healthy future through its graduates, research findings and inventions benefitting patients and the community. The University of Copenhagen wishes to reflect the surrounding community and invites all regardless of personal background to apply for the position.
Kilde: Jobnet.dk
The Department of Pharmacy, under the Faculty of Health and Medical Sciences, University of Copenhagen, invites applications for two PhD positions, for a period of 3 years, starting from 1st Oct, Nov or Dec 2021.
Job description
Proteins are versatile and highly potent drug candidates and account for a rapidly growing number of new drugs in development. Specialized analytical tools are needed to characterize these large and complex biomolecules. Hydrogen/deuterium exchange mass spectrometry (HDX-MS) has become an established analytical technique that can provide unique insights into the conformation, dynamics and interactions of proteins in solution. In a collaboration between the Protein Analysis Group and the Microscale Analytical Systems Group, we will develop microfluidic solutions to improve the HDX-MS method.
The overall aim of both PhD projects is to build on existing work in the group and develop and apply microfluidic components and couple these to mass spectrometry to realize an improved workflow for HDX-MS. The developed microfluidic HDX-MS solutions will be used to investigate several complex protein systems of therapeutic interest.
The two PhD candidates will work in the Protein Analysis Group under the supervision of Professor MSO Kasper Rand (primary supervisor), in close collaboration with the Microscale Analytical Systems Group (co-supervisors Prof. Jorg Kutter or Associate Professor Nickolaj Petersen). The two PhD fellowships are funded through a grant from the European Research Councils (ERC Consolidator Grant).
The key tasks as a PhD student are:
- Carry through an independent research project under supervision (see above)
- Complete PhD courses or other equivalent education corresponding to approx. 30 ECTS points
- Participate in active research environments including a stay at another research team
- Obtain experience with teaching or other types of dissemination related to your PhD project
- Teach and disseminate your knowledge
- Write a PhD thesis on the grounds of your project
Qualifications required
Applicants must have must have qualifications corresponding to a master’s degree within either of the following fields: microfluidics, analytical chemistry, protein mass spectrometry or HDX-MS. Applicants with lab-based experience within one or more of these areas will be preferred, particularly relevant is the field of microfluidics. The most successful applications will be those with experience with working at the interface between the fields of microfluidics, analytical chemistry and/or protein mass spectrometry/HDX-MS. Finally, the PhD candidates will be expected to engage in some teaching in analytical chemistry at either bachelor or master level courses.
Other important criteria are:
- The grade point average achieved
- Professional qualifications relevant to the PhD project
- Previous publications
- Relevant work experience
- Other professional activities
- Curious mind-set with a strong interest in the fields of study described above.
- Language skills
Further information
For further information, please contact either Professor MSO Kasper D. Rand ([email protected], tel. +45 2371 2556).
Place of employment
The Department of Pharmacy plays a key role in advancing the pharmaceutical sciences in Denmark and internationally. It is devoted to research and research-based teaching in drug formulation and manufacturing, drug-related analytical and physical chemistry, drug metabolism, chemical toxicolog and medicines use. The scientific and teaching objectives of the Department encompass the areas of Pharmaceutical Analytical Chemistry, Biopharmaceuticals/Biologics, Pharmaceutical Technology and Engineering; Pharmaceutical Design and Drug Delivery and Clinical and Social Pharmacy.
Terms of employment
The employment as PhD fellow is full time and for 3 years.
It is conditioned upon the applicant’s successful enrolment as a PhD student at the Graduate School at the Faculty of Health and Medical Sciences, University of Copenhagen. This requires submission and acceptance of an application for the specific project formulated by the applicant
The PhD study must be completed in accordance with The Ministerial Order on the PhD programme (2013) and the Faculty’s rules on achieving the degree. Salary, pension and terms of employment are in accordance with the agreement between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State. Depending on seniority, the monthly salary begins around 27.780 DKK /approx. 3.730 EUR (April 2021-level) plus pension.
As an equal opportunities, employer, the University of Copenhagen encourages all qualified applicants to apply, regardless of gender, age, religion and ethnic origin.
Application procedure
Your application must be submitted electronically by clicking ‘Apply now’ below. The application must include the following documents in PDF format:
1. Motivated letter of application (max. one page)
2. CV incl. education, experience, language skills and other skills relevant for the position
3. Master of Science diploma and transcript of records. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor will do
4. Publication list (if possible)
Application deadline: 12 July 2021, 23.59pm CET
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor.
The assessor makes a non-prioritized assessment of the academic qualifications and experience with respect to the above-mentioned area of research, techniques, skills and other requirements listed in the advertisement.
Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.
You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/
The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.
The Faculty of Health and Medical Sciences comprises approximately 7500 students, 1500 PhD students and 3200 employees. The Faculty advances the field of health sciences through its core activities: research, teaching, knowledge sharing and communication. With basic research fields ranging from molecular studies to studies of society, the Faculty contributes to a healthy future through its graduates, research findings and inventions benefitting patients and the community. The University of Copenhagen wishes to reflect the surrounding community and invites all regardless of personal background to apply for the position.
Kilde: Jobnet.dk
Information og data
Denne ledige stilling har jobtypen "Forsker", og befinder sig i kategorien "Sundhed og forskning".
Arbejdsstedet er beliggende i København Ø.
Jobbet er oprettet på vores service den 15.6.2021, men kan have været deaktiveret og genaktiveret igen.
Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
- Forsker
- København Ø
- Mandag den 12. juli 2021
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