Research Scientist with flair for protein characterisation and mass spectrometry

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Hørsholm

Would you like to make an impact on improving the quality of life of millions suffering from allergic diseases? Do you have flair for protein characterisation, an analytical mindset and would like to be part of a research department in constant development?

ALK is looking for a skilled protein chemist to join our Mass Spectrometry and Proteomics team. The team is placed in Biotechnology Research and takes part of early discovery and characterisation of potential leads, such as allergens/proteins, peptides, and small molecules, as well as supporting existing products and the ALK pipeline. With an open-minded approach, we characterise lead candidates by applying several analytical methods covering both general protein-chemical methods and more specialized analytical tools like MS, HPLC, DLS, immunoassays and more.

In this lab-based position, you will be working closely together with the experienced and skilled scientists and technicians within the department. You key scientific responsibility will be to analyse proteins by mass spectrometry methods for identification of proteins in complex mixtures and quantify changes over time. Further, your role will be to strengthen Biotechnology Research by contributing to ongoing research activities. To support the multitude of analytical methods, we expect that you are scientifically curious, proactive, a natural team player and possess strong personal collaboration skills.

Fields of responsibility

  • Apply MS-methods for identification, characterisation, and quantification (by absolute quantification, label-free and quantification with isobaric labels) of proteins and peptides in allergen extracts and complex mixtures.
  • Maintain LC-MS instrumentation.
  • Apply protein characterisation methods to analyse protein structure, protein stability, protein aggregation or protein binding.
  • Collaborate cross-functionally with Contract Research Organisation or other departments and functions outside Global Research e.g., CMC Development, Production, Medical and Regulatory affairs.
  • Actively participate in the scientific discussions across different projects, relevant international congresses, publish in international scientific journals and contribute to patents and innovations.
  • You are expected to work both independently and as a part of, multidisciplinary teams on several projects within Global Research

Your qualifications

  • Ph. D. in protein chemistry/biochemistry/medicinal chemistry/molecular biology or related fields.
  • Knowledge of LC-MS/MS analysis of biomolecules.
  • Experience with biopharmaceutical protein characterisation methods for example intact protein characterisation/PTM analysis.
  • Advantageous is experience with HPLC method development, Chromeleon software, immunoassay development (ELISA, MSD, Gyrolab) or biophysical characterisation of protein stability and aggregation
  • Basic understanding of statistics and experience with handling and interpreting large data sets are absolute advantages as is experience with design of experiments.
  • Experience in collaborating with various teams and Contract Research Organisation.
  • Excellent oral and written communication skills; highly organized and efficient record keeping.
  • Ability to provide clear reports and scientific direction to management, colleagues, and collaborators.

We offer

ALK provides a dynamic and pleasant work environment, complete with inspiring and challenging assignments. The results of your efforts will be significant throughout the organization, and you will be able to actively influence and challenge the status quo. Our flat structures attract independent individuals who like to feel the progress of the business and enjoy being close to the decision-making process. You will be part of an engaged and informal team who values skill and knowledge creation. We consider our pioneering spirit coupled with our trustworthiness our winning formula. ALK is a health focused organization, and our offices offer a green view of the DTU Science Park in Hørsholm.

Application deadline

22 April 2022

Contact

For further information on the position please contact Manager Kathrine Beck Sylvestersen +45 61 91 32 16


Information og data

Denne ledige stilling har jobtypen "Forretningsudvikler", og befinder sig i kategorien "Kommunikation, marketing, salg".

Arbejdsstedet er beliggende i Hørsholm.

Jobbet er oprettet på vores service den 16.3.2022, men kan have været deaktiveret og genaktiveret igen.

Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
  • Forretningsudvikler
  • Hørsholm

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