PhD fellowship in Medicinal Chemistry/Radiochemistry
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Department of Drug Design and Pharmacology
Faculty of Health and Medical Sciences (SUND)
University of Copenhagen
Department of Drug Design and Pharmacology is offering a three-year PhD fellowship in Medicinal Chemistry/Radiochemistry. The PhD fellowship is financed by the Danish Research Council. The fellowship is available from 15 October 2019 or as soon as possible thereafter.
Project description
g-Hydroxybutyric acid (GHB) is a naturally occurring compound in the mammalian brain. Already in 1982 it was reported that GHB binds with high affinity to a specific protein in the forebrain, but the molecular identity and functional relevance of this binding site has remained elusive. However, we have recently identified a GHB high-affinity target, which constitute a potential biomarker for PET imaging. The aim of this PhD project is to identify small-molecule candidates and develop suitable PET radiotracers by targeting the newly identified binding sites. Availability of such tools will enable early diagnose and optimal therapeutic intervention in implicated disease states.
The tasks during this project will thus include ligand design, chemical synthesis, radiochemistry and characterization of target compounds.
Principal supervisor
Professor Bente Frølund, Department of Drug Design and Pharmacology
E-mail: [email protected], direct phone: +45 3533 6495.
Information about the Department can be found at https://drug.ku.dk/.
Required qualifications
As an applicant you must have:
Preferred qualifications
We are looking for a highly motivated candidate with a documented strong background in organic synthesis and/or medicinal chemistry
Job description
Your key tasks as a PhD fellow at the Faculty are to:
Key criteria for the assessment of applicants
Formal requirements
The position is available for a 3-year period for applicants holding a relevant master´s degree.
The successful applicant will be requested to formally apply for enrolment as a PhD student at the Faculty of Health and Medical Sciences according to the rules stipulated in the Ministerial order on the PhD programme at the universities (PhD order) from the Ministry of Science, Innovation, and Higher Education and the guidelines for the PhD programme at the Faculty of Health and Medical Sciences.
The PhD student is expected to be affiliated to the graduate programme in pharmaceutical sciences, Drug Research Academy.
Terms of employment
The position as a PhD fellow is available for a 3-year period.
Salary and other terms and conditions of appointment are set in accordance with the Agreement between the Ministry of Finance and AC (Danish Confederation of Professional Associations) or other relevant professional organizations. Depending on seniority, the monthly salary begins around DKK 27,135 (approx. 3,618 EUR) (taxable) plus pension. The position is covered by the Job Structure for Academic Staff at Universities (2013).
Questions
For further information, applicants may contact the principal supervisor, Bente Frølund, or Administrator Marianne W. Jørgensen, e-mail: [email protected], direct phone: +45 3533 6449
For more information on working and living in Denmark visit http://ism.ku.dk (International staff mobility) and https://www.workindenmark.dk.
Application procedure
The application, in English, must be submitted electronically by clicking APPLY NOW below.
Your application must include:
The deadline for applications is 21 August 2019.
Please note that only online applications will be accepted. Applications received later than this date will not be considered.
The further process
Shortlist: After the expiry of the deadline for applications, the authorised recruitment manager selects applicants for assessment on the advice of the Appointment Committee. All applicants are then immediately notified whether their application has been passed for assessment by an expert assessment committee. Selected applicants are notified of the composition of the committee and each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself. You can read about the recruitment process at http://employment.ku.dk.
Assessment: The selected applications will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities and the University of Copenhagen’s guidelines 2013. The Assessment Committee makes a non-prioritised assessment of the academic qualifications and experience with respect to the mentioned area of research, techniques, skills and other requirements listed in the advertisement.
Please note that the applicant will be contacted if the assessment committee requires further documentation.
An answer as to the granting of the fellowship can be expected approx. 4 weeks after application deadline.
The Faculty of Health and Medical Sciences comprises approximately 7800 students, 1550 PhD students and 4400 employees. The Faculty advances the field of health sciences through its core activities: research, teaching, knowledge sharing and communication. With basic research fields ranging from molecular studies to studies of society, the Faculty contributes to a healthy future through its graduates, research findings and inventions benefitting patients and the community. The University of Copenhagen wishes to reflect the surrounding community and invites all regardless of personal background to apply for the position.
Kilde: Jobnet.dk
Faculty of Health and Medical Sciences (SUND)
University of Copenhagen
Department of Drug Design and Pharmacology is offering a three-year PhD fellowship in Medicinal Chemistry/Radiochemistry. The PhD fellowship is financed by the Danish Research Council. The fellowship is available from 15 October 2019 or as soon as possible thereafter.
Project description
g-Hydroxybutyric acid (GHB) is a naturally occurring compound in the mammalian brain. Already in 1982 it was reported that GHB binds with high affinity to a specific protein in the forebrain, but the molecular identity and functional relevance of this binding site has remained elusive. However, we have recently identified a GHB high-affinity target, which constitute a potential biomarker for PET imaging. The aim of this PhD project is to identify small-molecule candidates and develop suitable PET radiotracers by targeting the newly identified binding sites. Availability of such tools will enable early diagnose and optimal therapeutic intervention in implicated disease states.
The tasks during this project will thus include ligand design, chemical synthesis, radiochemistry and characterization of target compounds.
Principal supervisor
Professor Bente Frølund, Department of Drug Design and Pharmacology
E-mail: [email protected], direct phone: +45 3533 6495.
Information about the Department can be found at https://drug.ku.dk/.
Required qualifications
As an applicant you must have:
- Obtained a Master´s degree in medicinal chemistry, organic chemistry, or related areas prior to the starting date
- Documented experience with the synthesis of small molecules
- Fluency in English and excellent communication skills
Preferred qualifications
We are looking for a highly motivated candidate with a documented strong background in organic synthesis and/or medicinal chemistry
Job description
Your key tasks as a PhD fellow at the Faculty are to:
- Carry through an independent research project under supervision
- Write scientific articles and the PhD thesis on the grounds of your research project
- Complete PhD courses or other equivalent education corresponding to approx. 30 ECTS points
- Obtain experience with teaching or other types of dissemination related to your PhD project
- Participate in the undergraduate teaching of students in pharmaceutical sciences
- Participate in national and international conferences and scientific meetings
- Stay at an external research institution, preferably abroad
Key criteria for the assessment of applicants
- Professional qualifications relevant to the PhD project
- Relevant work experience
- Publications
- The grade point average achieved
- Other professional activities
- Language skills
- The successful applicant is also required to be enterprising and to possess good interpersonal skills
Formal requirements
The position is available for a 3-year period for applicants holding a relevant master´s degree.
The successful applicant will be requested to formally apply for enrolment as a PhD student at the Faculty of Health and Medical Sciences according to the rules stipulated in the Ministerial order on the PhD programme at the universities (PhD order) from the Ministry of Science, Innovation, and Higher Education and the guidelines for the PhD programme at the Faculty of Health and Medical Sciences.
The PhD student is expected to be affiliated to the graduate programme in pharmaceutical sciences, Drug Research Academy.
Terms of employment
The position as a PhD fellow is available for a 3-year period.
Salary and other terms and conditions of appointment are set in accordance with the Agreement between the Ministry of Finance and AC (Danish Confederation of Professional Associations) or other relevant professional organizations. Depending on seniority, the monthly salary begins around DKK 27,135 (approx. 3,618 EUR) (taxable) plus pension. The position is covered by the Job Structure for Academic Staff at Universities (2013).
Questions
For further information, applicants may contact the principal supervisor, Bente Frølund, or Administrator Marianne W. Jørgensen, e-mail: [email protected], direct phone: +45 3533 6449
For more information on working and living in Denmark visit http://ism.ku.dk (International staff mobility) and https://www.workindenmark.dk.
Application procedure
The application, in English, must be submitted electronically by clicking APPLY NOW below.
Your application must include:
- Cover letter: Letter stating the interest in and qualifications for the project (max. one page)
- Full CV
- Diploma and transcripts of records: Master´s degree diploma (including grade transcripts for bachelor´s and master´s degrees). Applicants with a Master´s degree from abroad should also enclose a short description of the grading scale used
- Possible publication list
- Other information to consider: Possible references and recommendations
The deadline for applications is 21 August 2019.
Please note that only online applications will be accepted. Applications received later than this date will not be considered.
The further process
Shortlist: After the expiry of the deadline for applications, the authorised recruitment manager selects applicants for assessment on the advice of the Appointment Committee. All applicants are then immediately notified whether their application has been passed for assessment by an expert assessment committee. Selected applicants are notified of the composition of the committee and each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself. You can read about the recruitment process at http://employment.ku.dk.
Assessment: The selected applications will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities and the University of Copenhagen’s guidelines 2013. The Assessment Committee makes a non-prioritised assessment of the academic qualifications and experience with respect to the mentioned area of research, techniques, skills and other requirements listed in the advertisement.
Please note that the applicant will be contacted if the assessment committee requires further documentation.
An answer as to the granting of the fellowship can be expected approx. 4 weeks after application deadline.
The Faculty of Health and Medical Sciences comprises approximately 7800 students, 1550 PhD students and 4400 employees. The Faculty advances the field of health sciences through its core activities: research, teaching, knowledge sharing and communication. With basic research fields ranging from molecular studies to studies of society, the Faculty contributes to a healthy future through its graduates, research findings and inventions benefitting patients and the community. The University of Copenhagen wishes to reflect the surrounding community and invites all regardless of personal background to apply for the position.
Kilde: Jobnet.dk
Information og data
Denne ledige stilling har jobtypen "Forsker", og befinder sig i kategorien "Sundhed og forskning".
Arbejdsstedet er beliggende i København Ø.
Jobbet er oprettet på vores service den 10.7.2019, men kan have været deaktiveret og genaktiveret igen.
Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
- Forsker
- København Ø
- Onsdag den 21. august 2019
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