Postdoc position in Integrative Physiology and Proteomics
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København N
Novo Nordisk Foundation Center for Basic Metabolic Research
Faculty of Health and Medical Sciences
University of Copenhagen
We are looking for a highly motivated and dynamic researcher for a postdoc position to start 19 November 2019.
Background
The Center was established in 2010 through a generous, unrestricted grant from the Novo Nordisk Foundation (NNF). The vision of the Center is to strengthen interdisciplinary research that transforms our basic understanding of the mechanisms of metabolic health and disease, and to accelerate this knowledge toward new prevention and treatment strategies. The Center has around 200 employees from all over the world. We moved into new laboratories, offices and meeting rooms in the Maersk Tower in summer 2017. In 2018, the Center obtained new strategic funding from NNF to further expand and establish/develop five enabling biology and technology platforms in support of the new research strategy. You can read more about us at http://cbmr.ku.dk.
The position is in the Zierath Group, which investigates the interactions between intrinsic biorhythms and external perturbations such as exercise, nutrient availability and temperature to identify potent translational strategies for prevention and treatment of metabolic diseases. The successful candidate will work closely with Dr. Atul Deshmukh to integrate proteomics and functional physiology, to answer basic and applied research questions related to circadian rhythms, metabolism and exercise. He or she will be embedded within CBMR and work in a scientific environment that bridges several disciplines of proteomics and metabolic diseases. You can read more about the Zierath Group at https://cbmr.ku.dk/research/integrative-metabolism-and-environmental-influences/zierath-group/.
Project description
Physical exercise provides numerous salutary effects against various chronic diseases, but the understanding of the mechanistic basis for the health benefits of exercise remains limited. Exercise improves the detrimental effects of obesity, prevents or delays the onset of type 2 diabetes (T2D), and has other metabolically beneficial effects in both non-healthy and healthy individuals. Furthermore, there is an emerging appreciation of circadian rhythmicity of skeletal muscle metabolism and the interaction between exercise and circadian rhythms to optimize the therapeutic effect of exercise.
The candidate who will use a range of models (cell, rodent and human), state-of-the-art proteomics technology and functional metabolic analyses to characterize circadian rhythmicity within skeletal muscle and identify important targets in the regulation of circadian rhythms and metabolic health.
Profile
We are looking for a highly motivated and enthusiastic scientist with the following competencies and qualifications:
The ideal candidate combine
Desirable criteria
Terms of employment
The postdoc position is a full-time position for 3 years. Starting date is 19 November 2019.
Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Depending on qualifications, a supplement may be negotiated.
Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.
The position is covered by the “Memorandum on Job Structure for Academic Staff at the Universities” of June 28, 2013.
Questions
For further information about the position, please contact Associate Professor Atul Deshmukh at [email protected]. For questions regarding the recruitment procedure, please contact SUND HR CBMR at [email protected].
International applicants may find these links useful www.ism.ku.dk (International Staff Mobility) and https://www.workindenmark.dk/.
Application procedure
Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:
Application deadline is 15 August 2019 at 23.59pm CET.
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether an unbiased assessor has passed their application for assessment. Once the assessment work has been completed, each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.
You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/.
The applicants will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.
The University of Copenhagen wishes to reflect the diversity of society and welcome applications from all qualified candidates regardless of personal background.
Kilde: Jobnet.dk
Faculty of Health and Medical Sciences
University of Copenhagen
We are looking for a highly motivated and dynamic researcher for a postdoc position to start 19 November 2019.
Background
The Center was established in 2010 through a generous, unrestricted grant from the Novo Nordisk Foundation (NNF). The vision of the Center is to strengthen interdisciplinary research that transforms our basic understanding of the mechanisms of metabolic health and disease, and to accelerate this knowledge toward new prevention and treatment strategies. The Center has around 200 employees from all over the world. We moved into new laboratories, offices and meeting rooms in the Maersk Tower in summer 2017. In 2018, the Center obtained new strategic funding from NNF to further expand and establish/develop five enabling biology and technology platforms in support of the new research strategy. You can read more about us at http://cbmr.ku.dk.
The position is in the Zierath Group, which investigates the interactions between intrinsic biorhythms and external perturbations such as exercise, nutrient availability and temperature to identify potent translational strategies for prevention and treatment of metabolic diseases. The successful candidate will work closely with Dr. Atul Deshmukh to integrate proteomics and functional physiology, to answer basic and applied research questions related to circadian rhythms, metabolism and exercise. He or she will be embedded within CBMR and work in a scientific environment that bridges several disciplines of proteomics and metabolic diseases. You can read more about the Zierath Group at https://cbmr.ku.dk/research/integrative-metabolism-and-environmental-influences/zierath-group/.
Project description
Physical exercise provides numerous salutary effects against various chronic diseases, but the understanding of the mechanistic basis for the health benefits of exercise remains limited. Exercise improves the detrimental effects of obesity, prevents or delays the onset of type 2 diabetes (T2D), and has other metabolically beneficial effects in both non-healthy and healthy individuals. Furthermore, there is an emerging appreciation of circadian rhythmicity of skeletal muscle metabolism and the interaction between exercise and circadian rhythms to optimize the therapeutic effect of exercise.
The candidate who will use a range of models (cell, rodent and human), state-of-the-art proteomics technology and functional metabolic analyses to characterize circadian rhythmicity within skeletal muscle and identify important targets in the regulation of circadian rhythms and metabolic health.
Profile
We are looking for a highly motivated and enthusiastic scientist with the following competencies and qualifications:
The ideal candidate combine
- PhD in exercise physiology, biochemistry, molecular biology, cell biology, or related science
- Experience in the analysis of circadian datasets
- Experience in the design, implementation and analyses of human exercise physiology studies
- Experience in molecular and cellular biology experiments within skeletal muscle tissue, such as immunoblotting, immunoprecipitations, qPCR, ELISAs and high-resolution respirometry
- Expertise in high resolution mass spectrometry and proteomics sample preparation
- Hands-on experience with Thermo HFX mass spectrometers and Thermo nLC 1200 systems
- Experience with bioinformatics proteomics data analysis (i.e., MaxQuant, Spectronaut and Perseus software)
- Knowledge of skeletal muscle biochemistry and exercise physiology
- Proven track record showing continuous scientific productivity in peer reviewed journals
- Independent thinking, and analytical aptitude for devising innovative scientific or technical solutions
- Excellent written and oral communication skills in English
Desirable criteria
- Experience in Python or another programming language
- Experience in experimental design, and planning of experiments
- Certified with FELASA laboratory animal science (or working towards certification)
- Additional background in exercise physiology and the measurement of proteins and post-translational modifications within skeletal muscle would be highly regarded
Terms of employment
The postdoc position is a full-time position for 3 years. Starting date is 19 November 2019.
Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Depending on qualifications, a supplement may be negotiated.
Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.
The position is covered by the “Memorandum on Job Structure for Academic Staff at the Universities” of June 28, 2013.
Questions
For further information about the position, please contact Associate Professor Atul Deshmukh at [email protected]. For questions regarding the recruitment procedure, please contact SUND HR CBMR at [email protected].
International applicants may find these links useful www.ism.ku.dk (International Staff Mobility) and https://www.workindenmark.dk/.
Application procedure
Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:
- Motivated letter of application (max. one page)
- Curriculum vitae (maximum of 2 pages; your ORCID must be included)
- Full list of publications (journal impact factors at publication date must be included)
- References (name and contact details of at least two references)
Application deadline is 15 August 2019 at 23.59pm CET.
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether an unbiased assessor has passed their application for assessment. Once the assessment work has been completed, each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.
You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/.
The applicants will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.
The University of Copenhagen wishes to reflect the diversity of society and welcome applications from all qualified candidates regardless of personal background.
Kilde: Jobnet.dk
Information og data
Denne ledige stilling har jobtypen "Akademisk medarbejder", og befinder sig i kategorien "Økonomi og jura".
Arbejdsstedet er beliggende i København N.
Jobbet er oprettet på vores service den 31.7.2019, men kan have været deaktiveret og genaktiveret igen.
Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
- Akademisk medarbejder
- København N
- Torsdag den 15. august 2019
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