PhD Student in Novel Bioreactor Configurations for Gas-Dependent Biocatalytic Reactions at DTU Chemical Engineering

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Studiejob - Kongens Lyngby

An important tool in the green transition is biocatalysis, whereby enzyme-catalyzed reactions enable entirely new syntheses to a range of valuable products.

The Department of Chemical and Biochemical Engineering (DTU Chemical Engineering) at the Technical University of Denmark offers a position as a PhD student in novel bioreactor configurations for gas-dependent biocatalytic reactions. This position will be hosted at DTU Chemical Engineering in a group which specializes is bioprocess scale-up and implementation. It will be part of an ERC Advanced Grant in the field of biocatalysis awarded to Professor John Woodley. This project will be integrated into the existing team. This PhD project aims to explore new bioreactor configurations to help overcome some of the challenges of enzymatic conversion using oxygen and other hydrophobic gases (including hydrogen, ammonia, carbon dioxide and methane). Laboratory and pilot experimentation will be used to help validate reactor concepts, complemented by models to help assess their potential.

Located in the Copenhagen area, one of the world's strongest biotech hubs, DTU offers a unique and internationally leading education and research environment with exceptional conditions for biotech career starters.

Project description
Biocatalytic oxidation is attracting enormous interest today in many parts of the chemical industry. Despite this interest, there remain several challenges for scale-up and implementation. In this project, the development of new equipment to facilitate hydrophobic gas-dependent reactions will be explored. Although biocatalytic oxidation using molecular oxygen will be at the center of this work, other gases such as hydrogen and carbon dioxide will also be evaluated. In this way, generic equipment will be established and benchmarked against stirred tanks, as a very valuable tool for those implementing such reactions in industry. Modelling tools and lab-scale experimentation will be complemented by pilot-scale experimentation (in the unique facilities at DTU Chemical Engineering).

Responsibilities and qualifications
As a PhD candidate working on this project you will:

  • Evaluate alternative bioreactor configurations for gas-dependent biocatalytic conversions
  • Develop lab-scale apparatus
  • Model the effects of kinetics and stability of the enzymes involved in gas-dependent biocatalysis
  • Predict scale-up effects
  • Test scale-up in the DTU Chemical Engineering pilot plant.


We are looking for a candidate with a solid background in:

  • Experimental bioprocess evaluation
  • Pilot scale operations for bioprocesses


Modelling and scale-up knowledge would be an added advantage.

You must have a two-year master's degree (120 ECTS points) or a similar degree with an academic level equivalent to a two-year master's degree.

Approval and Enrolment
The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see DTU's rules for the PhD education .

Assessment
The assessment of the applicants will be made by Prof John Woodley and approved by an internal PhD assessment committee.

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

Salary and appointment terms
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 3 years.

You can read more about career paths at DTU here http://www.dtu.dk/english/about/job-and-career/working-at-dtu/career-paths.

Further information
Further information may be obtained from Professor John Woodley, [email protected] , or +45 4525 2885.

You can read more about DTU Chemical Engineering at www.kt.dtu.dk/english.

If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark . Furthermore, you have the option of joining our monthly free seminar “PhD relocation to Denmark and startup “Zoom” seminar ” for all questions regarding the practical matters of moving to Denmark and working as a PhD at DTU.

Application procedure
Your complete online application must be submitted no later than 12 December 2022 (Danish time) . Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English in one PDF file . The file must include:

  • A letter motivating the application (cover letter)
  • Curriculum vitae
  • Grade transcripts and BSc/MSc diploma (in English) including official description of grading scale


You may apply prior to ob­tai­ning your master's degree but cannot begin before having received it.

Applications received after the deadline will not be considered.

All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply.

The Department of Chemical and Biochemical Engineering is one of the largest departments at DTU and hosts 6 research centers. The department is leading in innovative research and teaching, ranging from fundamental engineering disciplines to applied bio-based manufacturing processes. Our mission is to address important societal challenges through sustainable technological solutions. The department enjoys very close relations with international partners, and especially a wide range of industrial companies. DTU Chemical Engineering has approx. 230 employees, of which more than 1/3 is scientific staff and is expanding rapidly. The department is located at DTU Lyngby Campus.

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear mission to develop and create value using science and engineering to benefit society. That mission lives on today. DTU has 13,400 students and 5,800 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.

Kilde: Jobnet.dk


Information og data

Denne ledige stilling har jobtypen "Forsker", og befinder sig i kategorien "Sundhed og forskning".

Arbejdsstedet er beliggende i Kongens Lyngby.

Jobbet er oprettet på vores service den 29.11.2022, men kan have været deaktiveret og genaktiveret igen.

Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
  • Forsker
  • Kongens Lyngby
  • Mandag den 12. december 2022

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