Chemist/biochemist/engineer with experience in metabolomics to Biochemical Genetic Laboratory, Rigshospitalet
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København Ø
The Biochemical Genetic Laboratory at Department of Clinical Genetics, University Hospital Copenhagen, Rigshospitalet, has a full-time position open, for a biochemist, analytical chemist, engineer or like with experience (at Postdoc level) with High Resolution Mass Spectrometry (HRMS) in omics-based platforms. The candidate will join our team of biochemists and medical doctors involved in biochemical diagnosis and monitoring of inborn errors of metabolism (IEM).
The Biochemical Genetic Laboratory is a centralized laboratory for diagnostics of IEMs in Denmark, the Faroe Islands and Greenland. The laboratory analyses more than 10.000 patient samples yearly, using of a panel of targeted analyses, e.g. amino acids, acylcarnitines or organic acids, which are based on a variety of different sample preparations and analytical techniques (MS, MS/MS, UV etc.). The laboratory wishes to implement a single platform metabolomics, using only one (or few) tests instead of multiple highly targeted tests for screening of the metabolome. Single platform metabolomics is slowly emerging in the genetic biochemical laboratories worldwide and have been named next-generation metabolic screening (NGMS). The aim of NGMS is to identify and measure as many (IEM relevant) metabolites as possible, in order to generate a diagnostic metabolic fingerprint from one patient sample.
Challenges:
The position represents a unique opportunity to work with real clinical data with direct implication for patient diagnostic and treatment. As a highly specialized laboratory, we have a unique position in the field of precision and personalized medicine following the patient from sample to bedside. The duties will be equally divided between routine operations and the work of establishing a NGMS platform in the laboratory. At present the laboratory does not have HRMS instruments but is in the process of applying for funding. The laboratory has ongoing collaborating with international and national centers running NGMS.
Your tasks will be:
Qualifications:
Are you interested?
If you want to know more about the position contact Mette Christensen tlf: 3545 4333 or Flemming Wibrand tlf: 3545 4617.
The appointment will be based on collective agreement with the relevant union.
Application:
The application must reach us by 31 July 2021. Application in both English and Danish are welcomed. Those interested, regardless of age, gender, religion and ethnic affiliation, are encouraged to apply.
Apply for the position via the link on the page.
Kilde: Jobnet.dk
The Biochemical Genetic Laboratory is a centralized laboratory for diagnostics of IEMs in Denmark, the Faroe Islands and Greenland. The laboratory analyses more than 10.000 patient samples yearly, using of a panel of targeted analyses, e.g. amino acids, acylcarnitines or organic acids, which are based on a variety of different sample preparations and analytical techniques (MS, MS/MS, UV etc.). The laboratory wishes to implement a single platform metabolomics, using only one (or few) tests instead of multiple highly targeted tests for screening of the metabolome. Single platform metabolomics is slowly emerging in the genetic biochemical laboratories worldwide and have been named next-generation metabolic screening (NGMS). The aim of NGMS is to identify and measure as many (IEM relevant) metabolites as possible, in order to generate a diagnostic metabolic fingerprint from one patient sample.
Challenges:
The position represents a unique opportunity to work with real clinical data with direct implication for patient diagnostic and treatment. As a highly specialized laboratory, we have a unique position in the field of precision and personalized medicine following the patient from sample to bedside. The duties will be equally divided between routine operations and the work of establishing a NGMS platform in the laboratory. At present the laboratory does not have HRMS instruments but is in the process of applying for funding. The laboratory has ongoing collaborating with international and national centers running NGMS.
Your tasks will be:
- Interpretation and reporting of routine analyses
- Supporting existing workflows in the routine
- Upscaling the current collaboration around metabolomics/NGMS and looking into new possibilities.
- Implementing a pipeline for metabolomics for NGMS
- Handling and interpretation of metabolomics data
Qualifications:
- A degree in biochemistry, analytical chemistry, engineer or equivalent.
- Long experience (at Post-doc level or equivalent) with omics-based methods used in biochemistry, preferable metabolomics.
- Proficient in data-processing packages such as XCMS and/or computational and programming languages for handling of omics data (Phyton, R or equivalent)
- Basic skills in spoken and written Danish
- You are a team player but work independently and motivated by working in an interdisciplinary environment.
- Curious and passionate with a focus on high quality
- A basic understanding of mammal metabolism is welcomed
Are you interested?
If you want to know more about the position contact Mette Christensen tlf: 3545 4333 or Flemming Wibrand tlf: 3545 4617.
The appointment will be based on collective agreement with the relevant union.
Application:
The application must reach us by 31 July 2021. Application in both English and Danish are welcomed. Those interested, regardless of age, gender, religion and ethnic affiliation, are encouraged to apply.
Apply for the position via the link on the page.
Kilde: Jobnet.dk
Information og data
Denne ledige stilling har jobtypen "Kemiker", og befinder sig i kategorien "Sundhed og forskning".
Arbejdsstedet er beliggende i København Ø.
Jobbet er oprettet på vores service den 18.6.2021, men kan have været deaktiveret og genaktiveret igen.
Dagligt opdateret: Dette job opdateres dagligt ud fra jobudbyderens hjemmeside via vores søgemaskineteknologi og er aktivt lige nu.
- Kemiker
- København Ø
- Lørdag den 31. juli 2021
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